Coumadin and Dupuytren's contracture - a phase IV clinical study of FDA data
Summary:
Dupuytren's contracture is found among people who take Coumadin, especially for people who are male, 50-59 old.
The phase IV clinical study analyzes which people take Coumadin and have Dupuytren's contracture. It is created by eHealthMe based on reports of 127,156 people who have side effects when taking Coumadin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
127,156 people reported to have side effects when taking Coumadin.
Among them, 15 people (0.01%) have Dupuytren's contracture.
What is Coumadin?
Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. eHealthMe is studying from 130,032 Coumadin users for its effectiveness, alternative drugs and more.
What is Dupuytren's contracture?
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 445 drugs and 208 conditions by eHealthMe.
Number of Coumadin and Dupuytren's contracture reports submitted per year:

Gender of people who have Dupuytren's contracture when taking Coumadin *:
- female: 13.33 %
- male: 86.67 %
Age of people who have Dupuytren's contracture when taking Coumadin *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 60 %
- 60+: 40 %
Common drugs people take besides Coumadin *:
- Lisinopril: 9 people, 60.00%
- Plavix: 9 people, 60.00%
- Lopressor: 8 people, 53.33%
- Prednisone: 7 people, 46.67%
- Zometa: 6 people, 40.00%
- Taxotere: 6 people, 40.00%
- Neupogen: 6 people, 40.00%
- Oxycontin: 6 people, 40.00%
- Leuprolide Acetate: 6 people, 40.00%
- Mitoxantrone: 6 people, 40.00%
Common side effects people have besides Dupuytren's contracture *:
- Depression: 11 people, 73.33%
- Pain: 9 people, 60.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 60.00%
- Gait Disturbance: 9 people, 60.00%
- Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 9 people, 60.00%
- Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 46.67%
- Constipation: 7 people, 46.67%
- Hypotension (abnormally low blood pressure): 7 people, 46.67%
- Oedema (fluid collection in tissue): 7 people, 46.67%
- Diarrhea: 6 people, 40.00%
Common conditions people have *:
- Bone Density Decreased: 5 people, 33.33%
- Rash Pruritic (redness with itching): 3 people, 20.00%
- Psoriasis (immune-mediated disease that affects the skin): 2 people, 13.33%
- Stress And Anxiety: 1 person, 6.67%
- Pain: 1 person, 6.67%
- Osteoporosis (bones weak and more likely to break): 1 person, 6.67%
- Metastases To Bone (cancer spreads to bone): 1 person, 6.67%
- Infection: 1 person, 6.67%
- Depression: 1 person, 6.67%
- Colon Cancer: 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Coumadin and have Dupuytren's contracture?
Check whether Dupuytren's contracture is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Dupuytren's contracture and when was it recovered:
Expand to all the drugs that have ingredients of warfarin sodium:
Alternative drugs to, pros and cons of Coumadin:
- Coumadin (130,032 reports)
Common Coumadin side effects:
- Abasia (inability to walk): 504 reports
- Abdominal discomfort: 1,319 reports
- Abdominal distension: 1,317 reports
- Abdominal pain: 3,162 reports
- Abdominal pain lower: 234 reports
- Abdominal pain upper: 1,934 reports
- Abdominal tenderness: 106 reports
- Abnormal behavior: 166 reports
- Abnormal dreams: 129 reports
- Abortion spontaneous (naturally occurring miscarriage): 102 reports
- Abscess (pus): 363 reports
- Abscess jaw (tooth abscess or root abscess): 145 reports
- Accident: 103 reports
- Accidental overdose (therapeutic agent): 264 reports
- Acne (skin problems that cause pimples): 128 reports
- Actinic keratosis (skin disease due to sun exposure): 124 reports
- Actinomycosis (infection that causes sores, or abscesses): 189 reports
- Activated partial thromboplastin time prolonged: 506 reports
- Activities of daily living impaired: 368 reports
- Acute kidney failure: 2,802 reports
- Acute myocardial infarction (acute heart attack): 508 reports
- Acute pulmonary oedema (sudden deposit of fluid in the lung)): 103 reports
- Acute respiratory failure: 472 reports
- Acute upper airway obstruction (blockage occurs in the upper airway): 139 reports
- Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids): 146 reports
- Adverse drug reaction: 315 reports
- Adverse event: 759 reports
- Ageusia (loss of taste functions of the tongue): 167 reports
- Aggression: 171 reports
- Agitation (state of anxiety or nervous excitement): 655 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 978 reports
- Alanine aminotransferase increased: 970 reports
- Allergic rhinitis: 194 reports
- Anaemia (lack of blood): 5,481 reports
- Anaemia of chronic disease: 129 reports
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 251 reports
- Aneurysm (enlargement of an artery caused by a weakening of the artery wall): 162 reports
- Anger: 135 reports
- Angina unstable (chest pain due to ischemia of the heart muscle- unstable): 231 reports
- Angioedema (rapid swelling of the dermis): 110 reports
- Angiopathy (generic term for a disease of the blood vessels): 102 reports
- Anhedonia (inability to experience pleasure from activities usually found enjoyable): 1,260 reports
- Ankle fracture: 238 reports
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 491 reports
- Anticoagulation drug level above therapeutic: 193 reports
- Anticoagulation drug level below therapeutic: 119 reports
- Anuria (failure of the kidneys to produce urine): 103 reports
- Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall): 257 reports
- Aortic arteriosclerosis (hardening of the aortic arteries): 279 reports
- Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta): 323 reports
- Aortic valve incompetence: 343 reports
- Aortic valve replacement: 103 reports
- Aortic valve sclerosis (narrowing of the aortic valve): 127 reports
- Aphonia (inability to produce voice): 108 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 2,565 reports
- Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 121 reports
- Application site erythema (redness of the skin at application site): 101 reports
- Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system): 210 reports
- Arrhythmias (irregular heartbeat): 1,907 reports
- Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked): 145 reports
- Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery): 287 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 1,066 reports
- Arthropathy: 637 reports
- Ascites (accumulation of fluid in the abdominal cavity): 710 reports
- Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 893 reports
- Aspartate aminotransferase increased: 1,028 reports
- Asthma: 740 reports
- Atelectasis (partial or complete collapse of the lung): 1,045 reports
- Atherosclerosis (disorder of the arteries): 548 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5,780 reports
- Atrial tachycardia (rhythm disturbance that arises in the atria): 139 reports
- Atrioventricular block (heart block): 160 reports
- Atrioventricular block complete (heart block complete): 147 reports
- Atrioventricular block first degree (heart block first degree): 191 reports
- Azotaemia (excess of urea or other nitrogenous compounds in the blood): 184 reports
- Back disorder: 184 reports
- Back injury: 150 reports
- Back pain: 3,546 reports
- Bacteraemia (presence of bacteria in the blood): 284 reports
- Bacterial infection: 241 reports
- Balance disorder: 1,044 reports
- Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 280 reports
- Bedridden: 118 reports
- Belching (release of gas from the digestive tract): 170 reports
- Bell's palsy (facial paralysis): 102 reports
- Birth control: 235 reports
- Bladder cancer: 130 reports
- Bladder disorder: 140 reports
- Bleeding disorders: 1,167 reports
- Bleeding into the skin: 200 reports
- Blindness: 285 reports
- Blindness unilateral: 180 reports
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 490 reports
- Blockage of leg arteries: 147 reports
- Blood albumin decreased: 232 reports
- Blood alkaline phosphatase increased: 563 reports
- Blood alkaline phosphatase nos increased: 120 reports
- Blood bilirubin increased: 611 reports
- Blood calcium decreased: 286 reports
- Blood calcium increased: 148 reports
- Blood chloride decreased: 106 reports
- Blood creatine phosphokinase increased: 304 reports
- Blood creatinine increased: 1,285 reports
- Blood culture positive: 162 reports
- Blood disorder: 320 reports
- Blood glucose decreased: 515 reports
- Blood glucose fluctuation: 110 reports
- Blood glucose increased: 1,554 reports
- Blood in stool: 187 reports
- Blood iron decreased: 165 reports
- Blood lactate dehydrogenase increased: 221 reports
- Blood magnesium decreased: 197 reports
- Blood potassium decreased: 631 reports
- Blood pressure diastolic decreased: 167 reports
- Blood pressure fluctuation: 206 reports
- Blood pressure management: 286 reports
- Blood pressure systolic increased: 352 reports
- Blood sodium decreased: 327 reports
- Blood test: 172 reports
- Blood urea increased: 739 reports
- Blood urine present: 473 reports
- Body height decreased: 191 reports
- Body temperature decreased: 156 reports
- Body temperature increased: 233 reports
- Bone density decreased: 226 reports
- Bone disorder: 1,269 reports
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 444 reports
- Bone loss: 123 reports
- Bone marrow failure: 118 reports
- Bone pain: 801 reports
- Bradycardia (abnormally slow heart action): 1,212 reports
- Brain natriuretic peptide increased: 113 reports
- Breast cancer: 260 reports
- Breast cancer metastatic: 162 reports
- Breast lump (localized swelling that feels different from the surrounding breast tissue): 122 reports
- Breast pain: 140 reports
- Breathing difficulty: 10,725 reports
- Breathing - slowed or stopped: 249 reports
- Breath odor: 133 reports
- Broken bone: 266 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1,636 reports
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 209 reports
- Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle): 254 reports
- Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle): 213 reports
- Burning sensation: 520 reports
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 433 reports
- Cachexia (loss of weight): 110 reports
- Candidiasis (candidiasis or thrush is a fungal infection): 353 reports
- Cardiac arrest: 1,304 reports
- Cardiac disorder: 1,570 reports
- Cardiac failure: 1,365 reports
- Cardiac failure acute: 106 reports
- Cardiac failure congestive: 4,633 reports
- Cardiac flutter (abnormal heart rhythm): 141 reports
- Cardiac murmur (an heart sound in valve abnormality): 497 reports
- Cardiac valve disease (heart valve disease): 287 reports
- Cardioactive drug level increased: 186 reports
- Cardiogenic shock (inadequate circulation of blood): 237 reports
- Cardiomyopathy (weakening of the heart muscle): 665 reports
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 599 reports
- Cardioversion: 102 reports
- Carotid artery disease: 143 reports
- Carotid artery stenosis (narrowing of carotid artery): 295 reports
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling): 261 reports
- Cataract (clouding of the lens inside the eye): 1,008 reports
- Catheter related complication: 109 reports
- Catheter site discharge: 227 reports
- Catheter site erythema (redness of skin at catheter site): 406 reports
- Catheter site haemorrhage (bleeding at catheter site): 202 reports
- Catheter site infection (infection at the site of insertion): 316 reports
- Catheter site inflammation (infection at catheter site): 123 reports
- Catheter site pain: 277 reports
- Catheter site pruritus (itching at the site): 188 reports
- Catheter site swelling: 154 reports
- Cellulitis (infection under the skin): 1,794 reports
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord): 158 reports
- Cerebral atrophy (decrement in size of brain): 322 reports
- Cerebral haemorrhage (bleeding within the brain): 986 reports
- Cerebral infarction (less blood supply to brain resulting tissue damage): 308 reports
- Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand): 233 reports
- Cerebrovascular disorder (disease of brain): 155 reports
- Cervical spinal stenosis (narrowing of the spinal canal in the neck): 134 reports
- Chest pain: 5,369 reports
- Chills (felling of cold): 1,270 reports
- Cholecystitis (infection of gallbladder): 218 reports
- Cholecystitis chronic (long lasting infection of gallbladder): 106 reports
- Chronic kidney disease: 506 reports
- Chronic obstructive airways disease: 136 reports
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 1,513 reports
- Circulatory collapse: 157 reports
- Clostridial infection (infectious conditions by clostridium bacteria): 106 reports
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection): 232 reports
- Coagulation time prolonged: 114 reports
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 233 reports
- Colitis (inflammation of colon): 380 reports
- Colon cancer: 184 reports
- Colonic polyp (extra part of colon tissue grow in intestine): 298 reports
- Colonoscopy: 106 reports
- Common peroneal nerve dysfunction (dysfunction of nerve controlling movement and sensation to the lower leg, foot and toes): 101 reports
- Compression fracture (fracture due to pressure caused by injury): 356 reports
- Condition: 2,223 reports
- Confusion: 802 reports
- Confusional state: 1,962 reports
- Congestive cardiomyopathy (weakening of heart muscle): 154 reports
- Conjunctival haemorrhage (bleeding underneath the conjunctiva): 146 reports
- Conjunctivitis (pink eye): 126 reports
- Consciousness - decreased: 554 reports
- Constipation: 2,724 reports
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 805 reports
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly): 197 reports
- Coronary artery bypass: 136 reports
- Coronary artery occlusion (complete obstruction of blood flow in a coronary artery): 289 reports
- Coronary heart disease (narrowing or blockage of the coronary arteries): 1,091 reports
- Cor pulmonale (enlargement of the right ventricle of the heart): 128 reports
- Cough: 3,675 reports
- Coughing up blood: 1,170 reports
- C-reactive protein increased: 105 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 212 reports
- Crying: 160 reports
- Cuts and puncture wounds: 499 reports
- Cyst (a closed sac): 300 reports
- Death: 5,421 reports
- Decreased activity: 202 reports
- Decreased interest: 322 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2,878 reports
- Deformity (disfigurement): 731 reports
- Dehydration (dryness resulting from the removal of water): 2,884 reports
- Delirium (wild excitement): 257 reports
- Dementia (madness): 352 reports
- Dementia alzheimer's type (loss of mental ability with alzheimer's symptom): 114 reports
- Dental caries: 560 reports
- Dental fistula: 151 reports
- Depressed level of consciousness: 324 reports
- Depressed mood: 226 reports
- Depression: 2,468 reports
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 482 reports
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens): 261 reports
- Device dislocation: 323 reports
- Device failure: 110 reports
- Device occlusion: 284 reports
- Device related infection: 983 reports
- Diabetes: 788 reports
- Diabetes mellitus inadequate control: 278 reports
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 116 reports
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus): 144 reports
- Diarrhea: 6,573 reports
- Diarrhea haemorrhagic: 109 reports
- Diastolic dysfunction: 134 reports
- Difficulty in walking: 315 reports
- Dilatation ventricular: 232 reports
- Diplopia (double vision): 360 reports
- Disability: 389 reports
- Discomfort: 421 reports
- Disease progression: 918 reports
- Disease recurrence: 177 reports
- Disseminated intravascular coagulation (systemic activation of blood coagulation): 144 reports
- Disturbance in attention: 209 reports
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 463 reports
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body): 649 reports
- Diverticulum intestinal (a pouch that is attached to the first part of the small intestine): 255 reports
- Dizziness: 6,423 reports
- Dizziness (excl vertigo): 130 reports
- Dizziness postural: 170 reports
- Drowsiness: 1,479 reports
- Drug abuse and dependence: 258 reports
- Drug administration error: 261 reports
- Drug dependence: 185 reports
- Drug effect decreased: 394 reports
- Drug exposure during pregnancy: 110 reports
- Drug hypersensitivity: 752 reports
- Drug ineffective: 4,206 reports
- Drug intolerance (drug sensitivity): 346 reports
- Drug level increased: 147 reports
- Drug maladministration: 219 reports
- Drug toxicity: 436 reports
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 192 reports
- Dry eyes (lack of adequate tears): 249 reports
- Dry mouth: 786 reports
- Dry skin: 587 reports
- Dry throat: 105 reports
- Duodenitis (inflammation of the duodenum): 137 reports
- Dyskinesia (abnormality or impairment of voluntary movement): 251 reports
- Dyslipidaemia (abnormal amount of lipids): 177 reports
- Dyspnea exertional: 1,692 reports
- Dyspnea paroxysmal nocturnal: 117 reports
- Dysstasia (difficulty in standing): 321 reports
- Ear discomfort: 198 reports
- Ear pain: 320 reports
- Eating disorder: 278 reports
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath): 739 reports
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 135 reports
- Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat): 110 reports
- Ejection fraction decreased (systolic heart failure): 442 reports
- Electrocardiogram qt prolonged: 324 reports
- Electrolyte imbalance: 202 reports
- Embolic stroke (stroke due to obstruction due to an embolus): 128 reports
- Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 198 reports
- Emotional disorder: 259 reports
- Emotional distress: 1,488 reports
- Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 321 reports
- Encephalopathy (functioning of the brain is affected by some agent or condition): 279 reports
- Endocarditis (inflammation in heart muscle): 135 reports
- Enlarged heart: 1,095 reports
- Enlarged prostate: 255 reports
- Erection problems: 393 reports
- Erythema multiforme (a type of hypersensitivity reaction): 185 reports
- Escherichia infection (bacterial infection by escherichia coli): 111 reports
- Essential hypertension (primary hypertension): 123 reports
- Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury): 102 reports
- Excoriation (to tear or wear off the skin of): 147 reports
- Exercise tolerance decreased: 182 reports
- Exostosis (formation of new bone on the surface of a bone): 387 reports
- Exposed bone in jaw: 278 reports
- Extrasystoles: 197 reports
- Extremity contracture (permanent shortening of a muscle or joint of arms and legs): 142 reports
- Eye disorder: 213 reports
- Eye haemorrhage (bleeding in the eye): 324 reports
- Eye irritation: 156 reports
- Eye pain: 284 reports
- Eye swelling: 189 reports
- Face oedema (swelling of face): 226 reports
- Facial pain: 201 reports
- Faecal incontinence (a lack of control over passing stool): 173 reports
- Faecal occult blood positive: 111 reports
- Faeces discolored: 544 reports
- Failure to thrive (inadequate weight gain and physical growth in children): 201 reports
- Fainting (loss of consciousness and postural tone): 2,750 reports
- Fall: 6,236 reports
- Fatigue (feeling of tiredness): 8,363 reports
- Fear: 603 reports
- Febrile neutropenia (fever with reduced white blood cells): 387 reports
- Feeling cold: 301 reports
- Feeling hot: 513 reports
- Feeling jittery: 177 reports
- Femur fracture: 434 reports
- Fever: 3,779 reports
- Fibromyalgia (a long-term condition which causes pain all over the body): 283 reports
- Fibrosis (formation of excess fibrous connective tissue in an organ or tissue): 261 reports
- Fistula (an abnormal connection or passageway between two): 283 reports
- Flank pain (a distressing sensation experienced around the lower back and the upper abdomen): 259 reports
- Flatulence (flatus expelled through the anus): 599 reports
- Fluid overload (too much fluid in the blood): 1,039 reports
- Fluid retention (an abnormal accumulation of fluid in the blood): 2,125 reports
- Foot deformity (functional disability of foot): 128 reports
- Foot fracture: 262 reports
- Full blood count decreased: 174 reports
- Fungal infection: 370 reports
- Fungal nail infection: 147 reports
- Gait disturbance: 2,013 reports
- Gallbladder disorder: 332 reports
- Gallbladder removal: 192 reports
- Gallstones (stone formation by bile component): 777 reports
- Gamma-glutamyltransferase increased: 115 reports
- Gangrene (body tissue dies): 121 reports
- Gastric disorder (disease of stomach): 316 reports
- Gastric haemorrhage (bleeding stomach): 202 reports
- Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane): 109 reports
- Gastric ulcer (stomach ulcer): 890 reports
- Gastric ulcer haemorrhage (bleeding ulcer of stomach): 178 reports
- Gastritis (inflammation of stomach): 828 reports
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection): 146 reports
- Gastroenteritis (inflammation of stomach and intestine): 271 reports
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection): 241 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1,697 reports
- Gastrointestinal disorder (functional problems of gastrointestinal tract): 625 reports
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 3,868 reports
- Gastrointestinal perforation (hole in the digestive tract): 137 reports
- Generalised oedema (swelling all over the body): 203 reports
- General physical health deterioration (weak health status): 1,140 reports
- Gingival bleeding (bleeding gums): 546 reports
- Gingival disorder (gum disease): 207 reports
- Gingival infection (gum infection): 149 reports
- Gingival pain (gum pain): 199 reports
- Gingival ulceration (ulcer on gums): 148 reports
- Gingivitis (inflammation of gums): 274 reports
- Glaucoma (increased fluid pressure in the eye with vision loss): 278 reports
- Glossodynia (a burning or painful sensation in the tongue): 148 reports
- Glycosylated haemoglobin increased: 142 reports
- Gout (uric acid crystals building up in the body): 540 reports
- Grand mal convulsion (a type of generalized seizure that affects the entire brain): 128 reports
- Granuloma (a small area of inflammation due to tissue injury): 124 reports
- Groin pain: 185 reports
- Gums - swollen: 189 reports
- Gynecomastia (enlargement of the gland tissue of the male breast): 123 reports
- Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule): 142 reports
- Haematemesis (vomiting of blood): 692 reports
- Haematochezia (passage of stools containing blood): 806 reports
- Haematocrit decreased: 1,058 reports
- Haematoma (collection of blood outside the blood vessels): 1,534 reports
- Haematuria (presence of blood in urine): 1,311 reports
- Haematuria present (presence of blood in urine due to trauma): 320 reports
- Haemoglobin decreased: 2,624 reports
- Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid): 128 reports
- Haemorrhage (bleeding): 3,455 reports
- Haemorrhage intracranial (bleeding within the skull): 338 reports
- Haemorrhagic anaemia (anaemia due to excessive bleeding): 250 reports
- Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain): 494 reports
- Haemorrhoidal haemorrhage (bleeding from the haemorrhoids): 110 reports
- Haemorrhoids (a swollen vein or group of veins in the region of the anus): 810 reports
- Hair loss: 1,414 reports
- Hallucinations (sensations that appear real but are created by your mind): 550 reports
- Hallucination, visual (seeing things that aren't there): 134 reports
- Headache (pain in head): 6,442 reports
- Head injury: 3,173 reports
- Hearing impaired: 129 reports
- Hearing loss: 399 reports
- Heart attack: 2,752 reports
- Heart disease: 256 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 2,068 reports
- Heart rate decreased: 646 reports
- Heart rate increased: 1,542 reports
- Heart rate irregular: 843 reports
- Heart valve incompetence (heart's valves do not work correctly): 110 reports
- Heavy or prolong menstrual bleeding: 203 reports
- Hemiparesis (weakness on one side of the body): 352 reports
- Hemiplegia (paralysis of one side of the body): 151 reports
- Heparin-induced thrombocytopenia: 105 reports
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 233 reports
- Hepatic congestion (liver congestion): 106 reports
- Hepatic cyst: 242 reports
- Hepatic enzyme increased: 387 reports
- Hepatic failure (liver failure): 354 reports
- Hepatic lesion: 191 reports
- Hepatic steatosis (fatty liver disease): 285 reports
- Hepatitis (inflammation of the liver): 268 reports
- Hepatomegaly (abnormal enlargement of the liver): 259 reports
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle): 349 reports
- Herniated nucleus pulposus (slipped disk): 123 reports
- Herpes zoster: 717 reports
- Hiatal hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 682 reports
- High blood cholesterol: 1,016 reports
- High blood pressure: 3,965 reports
- Hip fracture: 661 reports
- Hip joint replacement: 191 reports
- Hoarseness or changing voice: 703 reports
- Hospitalisation: 937 reports
- Hot flush (sudden feelings of heat): 599 reports
- Humerus fracture (injury to the upper arm bone): 101 reports
- Hyperaesthesia: 150 reports
- Hypercalcaemia (elevated calcium (ca+) level in the blood): 216 reports
- Hypercoagulation (increased tendency for clotting of the blood): 245 reports
- Hyperglycemia (high blood sugar): 689 reports
- Hyperhidrosis (abnormally increased sweating): 1,089 reports
- Hyperkalemia (damage to or disease of the kidney): 1,160 reports
- Hyperkeratosis (thickening of the outer layer of the skin): 168 reports
- Hyperlipidaemia (presence of excess lipids in the blood): 766 reports
- Hypersensitivity: 977 reports
- Hypertensive crisis: 106 reports
- Hyperthyroidism (over activity of the thyroid gland): 179 reports
- Hypoacusis (loss of hearing): 290 reports
- Hypoaesthesia (reduced sense of touch or sensation): 1,941 reports
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth): 171 reports
- Hypocalcaemia (levels of calcium in blood serum are abnormally low): 301 reports
- Hypocoagulable state (abnormality of blood coagulation that increases the risk of thrombosis): 217 reports
- Hypoglycemia (low blood sugar): 824 reports
- Hypokalemia (low potassium): 1,129 reports
- Hypokinesia (decreased bodily movement): 137 reports
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 224 reports
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 933 reports
- Hypophagia (reduced food intake): 558 reports
- Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 109 reports
- Hypotension (abnormally low blood pressure): 5,150 reports
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 522 reports
- Hypovolaemia (a decreased volume of circulating blood in the body): 269 reports
- Hypovolaemic shock (shock caused by severe blood or fluid loss): 118 reports
- Hysterectomy: 110 reports
- Idiopathic pulmonary fibrosis (chronic lung disease): 463 reports
- Ill-defined disorder: 369 reports
- Impaired gastric emptying: 181 reports
- Impaired healing: 804 reports
- Impaired work ability: 142 reports
- Incontinence (lack of moderation or self-control): 156 reports
- Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone): 219 reports
- Indigestion: 1,282 reports
- Infection: 1,838 reports
- Inflammation: 549 reports
- Influenza like illness: 520 reports
- Infusion related reaction: 273 reports
- Infusion site erythema (reddening of the skin at infusion site): 251 reports
- Infusion site haemorrhage (bleeding from infusion site): 114 reports
- Infusion site infection: 159 reports
- Infusion site pain: 389 reports
- Infusion site swelling: 106 reports
- Injection site bruising: 403 reports
- Injection site erythema (redness at injection site): 361 reports
- Injection site haematoma (localized swelling filled with blood at injection site): 241 reports
- Injection site haemorrhage (bleeding from injection site): 525 reports
- Injection site mass: 121 reports
- Injection site pain: 630 reports
- Injection site pruritus (severe itching at injection site): 131 reports
- Injection site reaction: 165 reports
- Injection site swelling: 113 reports
- Injury: 2,458 reports
- Insomnia (sleeplessness): 2,256 reports
- International normalised ratio decreased: 1,986 reports
- International normalised ratio increased: 8,883 reports
- Interstitial lung disease: 361 reports
- Intervertebral disc degeneration (spinal disc degeneration): 701 reports
- Intervertebral disc disorder (spinal disc disorder): 120 reports
- Intervertebral disc protrusion (spinal disc protrusion): 645 reports
- Intestinal haemorrhage (bleeding from intestine): 107 reports
- Intestinal obstruction: 491 reports
- Intra-abdominal haemorrhage (intra-abdominal bleeding): 106 reports
- Intracardiac thrombus (presence of a circumscribed mass with heart wall): 170 reports
- Intracranial aneurysm (bulging, weak area in the wall of a cranial artery): 108 reports
- Iron deficiency anaemia: 358 reports
- Irritability: 223 reports
- Irritable bowel syndrome: 293 reports
- Ischaemia (insufficient supply of blood to an organ, usually due to a blocked artery): 155 reports
- Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease): 235 reports
- Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain): 254 reports
- Itching: 2,206 reports
- Jaundice - yellow skin (a yellowish pigmentation of the skin): 330 reports
- Jaw disorder (jaw disease): 204 reports
- Jaw fracture: 224 reports
- Joint contracture (a permanent shortening of a muscle or joint): 254 reports
- Joint dislocation (a joint position is changed from normal position): 162 reports
- Joint effusion (presence of extra fluid in joint covering): 228 reports
- Joint injury: 317 reports
- Joint pain: 3,718 reports
- Joint range of motion decreased (disease of joint movement): 418 reports
- Joint stiffness: 416 reports
- Joint swelling: 1,038 reports
- Kidney infection: 195 reports
- Kidney infection (pyelonephritis): 110 reports
- Kidney stones: 633 reports
- Knee joint replacement: 209 reports
- Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back)): 248 reports
- Lacrimation increased: 209 reports
- Lactic acidosis (low ph in body tissues): 162 reports
- Lacunar infarction (type of stroke): 104 reports
- Left ventricular dysfunction: 299 reports
- Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 379 reports
- Leukocytosis (increased white blood cells): 384 reports
- Leukopenia (less number of white blood cells in blood): 433 reports
- Ligament sprain (ligament stretched): 117 reports
- Limb discomfort (discomfort in leg): 286 reports
- Limb injury: 354 reports
- Lipase increased: 103 reports
- Lip swelling: 119 reports
- Liver disorder (liver diseases): 259 reports
- Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung): 172 reports
- Localised infection (infection at the single location): 343 reports
- Local swelling (swelling at the site of some application of substance or injury): 393 reports
- Loose tooth: 264 reports
- Loss of consciousness: 1,689 reports
- Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding): 272 reports
- Lower limb fracture: 206 reports
- Lower respiratory tract infection: 130 reports
- Low tissue oxygen: 1,094 reports
- Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone): 256 reports
- Lumbar vertebral fracture: 109 reports
- Lump in the abdomen (an area of swelling or growth on abdomen): 107 reports
- Lung disorder (lung disease): 729 reports
- Lung infection: 252 reports
- Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 614 reports
- Lung neoplasm (tumour of lung): 358 reports
- Lung neoplasm malignant (cancer tumour of lung): 216 reports
- Lung transplant: 115 reports
- Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 554 reports
- Lymphocyte count decreased: 101 reports
- Lymphoedema (localized fluid retention and tissue swelling): 215 reports
- Lymphoma (cancer that begins in immune system cells): 194 reports
- Macular degeneration (painless eye condition that leads to the gradual loss of central vision): 221 reports
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 101 reports
- Malaise (a feeling of general discomfort or uneasiness): 3,822 reports
- Malignant melanoma (skin cancer rises from melancytes): 118 reports
- Malignant neoplasm progression (cancer tumour came back): 588 reports
- Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 363 reports
- Mastication disorder (disease of chewing food): 211 reports
- Medical device complication: 263 reports
- Melaena (the passage of black, tarry stools): 881 reports
- Memory loss: 1,607 reports
- Meniscus lesion (lesion of a crescent-shaped piece of cartilage between the femur and the tibia): 103 reports
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 319 reports
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 223 reports
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 828 reports
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 380 reports
- Metastases to bone (cancer spreads to bone): 593 reports
- Metastases to central nervous system (cancer spreads to central nervous system): 245 reports
- Metastases to liver (cancer spreads to liver): 350 reports
- Metastases to lung (cancer spreads to lung): 215 reports
- Metastases to lymph nodes (cancer spreads to lymph node): 127 reports
- Metastases to spine (cancer spreads to spine): 252 reports
- Metastatic neoplasm (spreadable cancer tumour): 103 reports
- Micturition urgency (urgency to pass the urine): 186 reports
- Migraine (headache): 650 reports
- Mitral valve calcification (calcium deposit in mitral valve): 137 reports
- Mitral valve disease (disease of mitral valve of heart): 122 reports
- Mitral valve incompetence (inefficient heart valve): 1,153 reports
- Mitral valve prolapse (heart's mitral valve doesn't work well): 104 reports
- Mobility decreased (ability to move is reduced): 700 reports
- Mood swings (an extreme or rapid change in mood): 224 reports
- Mouth haemorrhage (bleeding from mouth): 297 reports
- Mouth ulcers: 322 reports
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 229 reports
- Movement - uncoordinated: 186 reports
- Mucosal inflammation (infection of mucous membrane): 295 reports
- Multi-organ failure (multisystem organ failure): 571 reports
- Multiple injuries: 558 reports
- Multiple myeloma (cancer of the plasma cells): 680 reports
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 177 reports
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 191 reports
- Muscle aches (muscle pain): 1,763 reports
- Muscle atrophy (a decrease in the mass of the muscle): 156 reports
- Muscle cramps (painful sensations caused by muscle contraction): 204 reports
- Muscle function loss: 155 reports
- Muscle haemorrhage (bleeding in muscle): 216 reports
- Muscle spasms (muscle contraction): 1,703 reports
- Muscle strain (an injury to a muscle in which the muscle fibres tear): 209 reports
- Muscle tightness: 178 reports
- Muscle twitching: 185 reports
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones): 462 reports
- Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 401 reports
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves): 154 reports
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 1,155 reports
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 671 reports
- Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 178 reports
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 338 reports
- Myopathy (a muscular disease in which the muscle fibres do not function): 148 reports
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 1,053 reports
- Nasopharyngitis (inflammation of the nasopharynx): 1,666 reports
- Nausea (feeling of having an urge to vomit): 8,036 reports
- Nausea and vomiting: 4,365 reports
- Neck pain: 965 reports
- Necrosis (the death of body tissue): 181 reports
- Neoplasm malignant (cancer tumour): 676 reports
- Neoplasm progression (growth of tumour): 191 reports
- Nephrogenic anaemia (anaemia due to kidney disease): 138 reports
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease): 756 reports
- Nephropathy (damage to or disease of a kidney): 117 reports
- Nervousness: 594 reports
- Nervous system disorder (a general class of medical conditions affecting the nervous system): 178 reports
- Neuralgia (pain in one or more nerves): 259 reports
- Neuropathy peripheral (surface nerve damage): 1,499 reports
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 186 reports
- Nightmares (unpleasant dreams): 150 reports
- Night sweats (sweating in night): 332 reports
- Nodule (a small rock or mineral cluster): 155 reports
- Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits): 112 reports
- Nosebleed (bleeding from nose): 2,990 reports
- Numbness and tingling (unusual prickling sensations): 138 reports
- Obstructive airways disorder (a progressive disease that makes it hard to breathe): 129 reports
- Occult blood positive: 112 reports
- Ocular hyperaemia (an abnormally large amount of blood in eye): 255 reports
- Oedema (fluid collection in tissue): 2,022 reports
- Oedema lower limb (fluid collection in tissue of lower leg): 370 reports
- Oedema mouth (swelling of mouth): 110 reports
- Oedema peripheral (superficial swelling): 4,784 reports
- Oesophageal pain: 102 reports
- Oesophageal ulcer (ulcer of oesophagus): 143 reports
- Oesophagitis (inflammation of oesophagus): 350 reports
- Oral candidiasis (fungal infection of mouth): 252 reports
- Oral cavity fistula (an abnormal opening in mouth): 112 reports
- Oral discomfort (pain or irritation in mouth): 167 reports
- Oral disorder (mouth disease): 252 reports
- Oral herpes (viral infection of mouth): 135 reports
- Oral infection: 187 reports
- Oral pain: 488 reports
- Oral surgery: 109 reports
- Oropharyngeal pain: 816 reports
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 348 reports
- Osteitis (a general term for inflammation of bone): 180 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1,448 reports
- Osteolysis (dissolution of bone): 300 reports
- Osteomyelitis (infection of bone): 1,190 reports
- Osteonecrosis of jaw (death of bone of jaw): 1,586 reports
- Osteopenia (a condition where bone mineral density is lower than normal): 695 reports
- Osteoporosis (bones weak and more likely to break): 756 reports
- Osteoradionecrosis (irradiation of bones causes damage to osteocytes and impairs the blood supply): 106 reports
- Osteosclerosis (an elevation in bone density): 259 reports
- Otitis (ear infection): 287 reports
- Ovarian cysts (fluid filled sacs of the ovary): 170 reports
- Overdose: 1,141 reports
- Oxygen saturation decreased: 1,047 reports
- Pain: 6,585 reports
- Pain in extremity: 4,166 reports
- Pain in jaw: 1,907 reports
- Pain in limb: 290 reports
- Pain of skin: 148 reports
- Paleness (unusual lightness of skin colour): 415 reports
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome): 190 reports
- Pancreatitis (inflammation of pancreas): 509 reports
- Pancreatitis acute (sudden inflammation of pancreas): 157 reports
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 911 reports
- Panic disorder: 255 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 1,570 reports
- Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect): 107 reports
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 117 reports
- Parkinson's disease: 193 reports
- Paroxysmal supraventricular tachycardia: 256 reports
- Pathological fracture (broken bone caused by disease): 351 reports
- Pelvic pain: 155 reports
- Pericardial effusion (fluid around the heart): 653 reports
- Pericarditis (inflammation of the pericardium): 116 reports
- Periodontal disease (disease that attacks the gum and bone and around the teeth): 205 reports
- Periodontitis (inflammation of the tissue around the teeth): 213 reports
- Peripheral coldness: 183 reports
- Peripheral ischaemia (impaired circulation to an extremity): 102 reports
- Peripheral neuropathy (damage to nerves of the peripheral nervous system): 143 reports
- Peripheral swelling: 1,206 reports
- Peripheral vascular disorder: 317 reports
- Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 143 reports
- Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 120 reports
- Pharyngitis (inflammation of the pharynx, causing a sore throat): 163 reports
- Pharyngolaryngeal pain: 116 reports
- Photophobia (extreme sensitivity to light): 142 reports
- Photosensitivity reaction: 112 reports
- Physical disability: 212 reports
- Platelet count increased: 206 reports
- Pleural effusion (water on the lungs): 2,109 reports
- Pleural fibrosis (formation of fibrous tissue in lung): 130 reports
- Pleurisy (inflammation of the pleurae, which causes pain when breathing): 131 reports
- Pleuritic pain: 118 reports
- Pneumonia: 5,975 reports
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 278 reports
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 245 reports
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 507 reports
- Polyp: 208 reports
- Poor quality sleep: 135 reports
- Post procedural complication: 319 reports
- Post procedural haemorrhage (post procedural bleeding): 259 reports
- Pressure ulcer: 279 reports
- Presyncope: 745 reports
- Primary pulmonary hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1,145 reports
- Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone): 424 reports
- Procedural complication: 101 reports
- Proctalgia (pain in the rectum): 102 reports
- Productive cough: 713 reports
- Prostate cancer: 195 reports
- Prostatic specific antigen increased: 173 reports
- Prostatomegaly (enlargement of the prostate): 121 reports
- Protein - urine: 163 reports
- Prothrombin level decreased: 502 reports
- Prothrombin level increased: 256 reports
- Prothrombin time shortened: 239 reports
- Pruritus generalised (generalized itching): 219 reports
- Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 146 reports
- Psoriasis (immune-mediated disease that affects the skin): 232 reports
- Psychotic disorder: 129 reports
- Pulmonary arterial pressure increased: 124 reports
- Pulmonary congestion (congestion in the lungs): 436 reports
- Pulmonary embolism (blockage of the main artery of the lung): 2,988 reports
- Pulmonary haemorrhage (acute bleeding from the lung): 195 reports
- Pulmonary hypertension (increase in blood pressure in the lung artery): 1,535 reports
- Pulmonary mass: 203 reports
- Pulmonary oedema (fluid accumulation in the lungs): 1,310 reports
- Pulmonary thrombosis (scarring in the lungs): 382 reports
- Pulmonary valve incompetence: 119 reports
- Pulse absent: 150 reports
- Purpura (purplish discoloration of the skin): 137 reports
- Purulence (containing pus): 116 reports
- Purulent discharge (discharge that contains pus): 286 reports
- Quality of life decreased: 153 reports
- Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 165 reports
- Rales (an abnormal respiratory sound characterized by fine crackles): 250 reports
- Rash erythematous (redness of the skin): 387 reports
- Rashes (redness): 4,349 reports
- Rash macular (small, flat red spots): 305 reports
- Rash maculo-papular (red area on the skin that is covered with small confluent bumps): 151 reports
- Rash papular (redness with papule): 165 reports
- Rash pruritic (redness with itching): 530 reports
- Rectal bleeding (bleeding from rectum): 193 reports
- Rectal haemorrhage (bleeding from anus): 1,658 reports
- Red blood cell count decreased: 442 reports
- Renal cell carcinoma (a kidney cancer): 146 reports
- Renal cyst (kidney cyst): 538 reports
- Renal disorder (kidney disease): 596 reports
- Renal failure acute (rapid kidney dysfunction): 1,864 reports
- Renal failure chronic (long lasting kidney dysfunction): 720 reports
- Renal impairment (severely reduced kidney function): 980 reports
- Renal injury (kidney injury): 520 reports
- Renal tubular necrosis (death of kidney tubules): 203 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 1,507 reports
- Respiratory disorder (respiratory disease): 304 reports
- Respiratory distress (difficulty in breathing): 553 reports
- Respiratory rate increased (excess breathing rate/min): 204 reports
- Respiratory tract congestion (blockage on respiratory system): 222 reports
- Respiratory tract infection: 237 reports
- Restless leg syndrome (a powerful urge to move your legs): 359 reports
- Retching (strong involuntary effort to vomit): 267 reports
- Retroperitoneal haematoma (blood clot between the peritoneum and the posterior abdominal wall): 113 reports
- Retroperitoneal haemorrhage (bleeding between the peritoneum and the posterior abdominal wall): 233 reports
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 417 reports
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 371 reports
- Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 173 reports
- Rib fracture: 678 reports
- Rickets (softening of bones): 118 reports
- Right ventricular failure (right half of the heart fails to work): 579 reports
- Road traffic accident: 450 reports
- Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder): 475 reports
- Scar: 416 reports
- Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 292 reports
- Scoliosis (a medical condition in which a person's spine is curved from side to side): 394 reports
- Seasonal allergy (allergic condition due to certain season): 211 reports
- Secretion discharge: 120 reports
- Sedation: 290 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 229 reports
- Sensitivity of teeth: 112 reports
- Sensory disturbance (sense disturbance): 105 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 1,880 reports
- Septic shock (shock due to blood infection): 471 reports
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 151 reports
- Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding): 173 reports
- Sick sinus syndrome (a collection of heart rhythm disorders): 231 reports
- Sinus bradycardia (an unusually slow heartbeat due to heart disease): 332 reports
- Sinus congestion (blockage of sinus): 199 reports
- Sinus disorder (disease of sinus): 416 reports
- Sinusitis (inflammation of sinus): 1,605 reports
- Sinusitis - chronic: 105 reports
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 427 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 1,783 reports
- Skin burning sensation: 173 reports
- Skin cancer: 190 reports
- Skin - clammy: 129 reports
- Skin discoloration: 827 reports
- Skin discoloration - bluish (bluish colour of skin): 307 reports
- Skin disorder (skin disease): 322 reports
- Skin exfoliation (removal of the oldest dead skin cells): 410 reports
- Skin fibrosis (fibrous tissue formation on skin): 182 reports
- Skin haemorrhage (bleeding into skin): 118 reports
- Skin hyperpigmentation (disorders affect the colour of your skin): 230 reports
- Skin hypertrophy (skin cells enlarges): 393 reports
- Skin induration (an abnormally hard spot or area on the skin): 391 reports
- Skin infection: 140 reports
- Skin irritation: 112 reports
- Skin necrosis (skin damage): 141 reports
- Skin plaque (red, scaly patches to appear on the skin): 131 reports
- Skin tightness: 362 reports
- Skin ulcer: 629 reports
- Sleep apnea syndrome: 661 reports
- Sleep disorder: 436 reports
- Small intestinal obstruction (blockage in small intestine): 332 reports
- Sneezing: 162 reports
- Soft tissue disorder (disease of soft tissue): 114 reports
- Sopor (sleep): 220 reports
- Speech disorder: 557 reports
- Speech impairment (adult) (inability to speak (adult)): 857 reports
- Spinal column stenosis (narrowing of spinal column): 267 reports
- Spinal compression fracture (fracture due to spinal compression on bone): 342 reports
- Spinal cord compression: 143 reports
- Spinal disorder (disease of spine a back bone): 185 reports
- Spinal fracture (fracture in one of vertebrae): 344 reports
- Spinal osteoarthritis (joint cartilage loss in spine): 862 reports
- Splenomegaly (enlargement of spleen): 241 reports
- Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below): 220 reports
- Sputum discolored: 146 reports
- Squamous cell carcinoma (a cancer of a kind of epithelial cell): 194 reports
- Stable angina (a constant chest pain): 555 reports
- Staphylococcal bacteraemia (a bacterial infection of blood): 142 reports
- Staphylococcal infection (an infection with staphylococcus bacteria): 759 reports
- Stem cell transplant: 143 reports
- Stent: 185 reports
- Stomach discomfort (pain in abdomen): 124 reports
- Stomatitis (inflammation of mucous membrane of mouth): 573 reports
- Stress and anxiety: 4,492 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3,178 reports
- Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain): 274 reports
- Subdural haematoma (blood collects between the skull and the surface of the brain): 805 reports
- Suicidal ideation: 335 reports
- Suicide attempt: 134 reports
- Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle): 169 reports
- Surgery: 585 reports
- Swallowing difficulty: 1,449 reports
- Swallowing pain or burning: 116 reports
- Sweating increased (excess sweating): 226 reports
- Swelling: 1,446 reports
- Swelling face: 529 reports
- Swollen tongue (swelling of tongue): 158 reports
- Synovial cyst (cyst of joint filled with synovial fluid): 165 reports
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 265 reports
- Systemic sclerosis (scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 108 reports
- Tachypnea: 139 reports
- Taste - impaired: 656 reports
- Tenderness (pain or discomfort when an affected area is touched): 373 reports
- Tendon disorder (disease of tendon): 106 reports
- Tendonitis (a condition that causes pain and swelling of tendons): 189 reports
- The flu (the flu is caused by an influenza virus): 1,032 reports
- Therapeutic agent toxicity (poisoning by ability to cure substance): 402 reports
- Therapeutic response decreased (less preventive response): 306 reports
- Therapeutic response unexpected: 175 reports
- Thirst: 121 reports
- Throat irritation: 409 reports
- Throat tightness: 157 reports
- Thrombocytopenia (decrease of platelets in blood): 2,804 reports
- Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 421 reports
- Thrombosis (formation of a blood clot inside a blood vessel): 2,686 reports
- Thyroid diseases: 231 reports
- Tinnitus (a ringing in the ears): 378 reports
- Tooth abscess (pus formation in tooth): 633 reports
- Toothaches (tooth pain): 417 reports
- Tooth disorder (tooth disease): 530 reports
- Tooth extraction: 829 reports
- Tooth fracture: 326 reports
- Tooth loss: 350 reports
- Torsade de pointes (a abnormal heart rate with abnormal beating pattern): 161 reports
- Transaminases increased: 126 reports
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 1,216 reports
- Traumatic injury of the bladder and urethra: 207 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 1,485 reports
- Tricuspid valve incompetence (inefficient heart valve): 812 reports
- Troponin increased: 112 reports
- Tumor: 501 reports
- Type 2 diabetes: 431 reports
- Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 177 reports
- Ulcer haemorrhage (bleeding ulcer): 173 reports
- Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button): 110 reports
- Unilateral hydronephrosis (kidney stone that causes obstruction of the ureter): 225 reports
- Unresponsive to stimuli: 373 reports
- Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding): 534 reports
- Upper limb fracture: 313 reports
- Upper respiratory tract infection: 943 reports
- Urinary incontinence (inability to control the flow of urine and involuntary urination): 497 reports
- Urinary retention (the inability to completely or partially empty the bladder): 532 reports
- Urinary tract infection: 3,145 reports
- Urination - excessive at night: 238 reports
- Urination - excessive volume: 150 reports
- Urination - painful: 611 reports
- Urine output decreased: 147 reports
- Urine output - decreased: 128 reports
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 173 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 686 reports
- Uterine leiomyoma (uterine benign tumour derived from smooth muscle): 126 reports
- Vaginal bleeding: 437 reports
- Vasculitis (inflammation of a blood vessel or blood vessels): 182 reports
- Venous insufficiency (poor circulation of blood caused by damaged or enlarged veins): 164 reports
- Venous thrombosis (blood clot (thrombus) that forms within a vein): 139 reports
- Venous thrombosis deep limb (blood clot that forms in a vein deep in the limb): 190 reports
- Ventricular extrasystoles (premature cardiac contraction): 432 reports
- Ventricular fibrillation (abnormally irregular heart rhythm): 345 reports
- Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart): 223 reports
- Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do): 143 reports
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 654 reports
- Vertebral foraminal stenosis (narrowing of the intervertebral foramen): 106 reports
- Viral infection: 444 reports
- Vision blurred: 1,374 reports
- Visual acuity reduced (reduced clearness of vision): 420 reports
- Visual disturbance: 160 reports
- Visual impairment: 659 reports
- Vitreous floaters (spots before the eyes): 132 reports
- Wax blockage: 132 reports
- Weakness: 7,924 reports
- Weight decreased: 3,723 reports
- Weight increased: 2,168 reports
- Weight loss: 379 reports
- Wheezing (a high-pitched whistling sound made while you breath): 712 reports
- White blood cell count decreased: 841 reports
- White blood cell count increased: 578 reports
- Wound: 309 reports
- Wound dehiscence (a surgical incision reopens either internally or externally): 151 reports
- Wound infection: 207 reports
- Wrist fracture: 148 reports
Browse all side effects of Coumadin:
a b c d e f g h i j k l m n o p q r s t u v w x y zDupuytren's contracture treatments and more:
- Dupuytren's contracture (2,031 reports)
COVID vaccines that are related to Dupuytren's contracture:
- Dupuytren's contracture in Moderna COVID Vaccine
- Dupuytren's contracture in Pfizer BioNTech Covid Vaccine
- Dupuytren's contracture in Johnson and Johnson Covid Vaccine
Common drugs associated with Dupuytren's contracture:
- Xiaflex: 137 reports
All the drugs that are associated with Dupuytren's contracture:
- Dupuytren's contracture (445 drugs)
Common conditions associated with Dupuytren's contracture:
- Ra: 104 reports
All the conditions that are associated with Dupuytren's contracture:
- Dupuytren's contracture (208 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on warfarin sodium (the active ingredients of Coumadin) and Coumadin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
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