Coumadin and Osteonecrosis of jaw - from FDA reports


Osteonecrosis of jaw is found among people who take Coumadin, especially for people who are female, 60+ old , have been taking the drug for 5 - 10 years, also take medication Zometa, and have Multiple myeloma. This study is created by eHealthMe based on reports of 112,498 people who have side effects when taking Coumadin from FDA, and is updated regularly.

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On Nov, 16, 2018

112,498 people reported to have side effects when taking Coumadin.
Among them, 1,567 people (1.39%) have Osteonecrosis of jaw


Number of reports submitted per year:

Could Coumadin cause Osteonecrosis of jaw?

Time on Coumadin when people have Osteonecrosis of jaw *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

Gender of people who have Osteonecrosis of jaw when taking Coumadin *:

  • female: 62 %
  • male: 38 %

Age of people who have Osteonecrosis of jaw when taking Coumadin *:

  • 0-1: 0.0 %
  • 2-9: 0.08 %
  • 10-19: 0.5 %
  • 20-29: 1.16 %
  • 30-39: 1.49 %
  • 40-49: 14.43 %
  • 50-59: 37.4 %
  • 60+: 44.94 %

Top conditions involved for these people *:

  1. Multiple Myeloma (cancer of the plasma cells): 407 people, 25.97%
  2. Metastases To Bone (cancer spreads to bone): 239 people, 15.25%
  3. Breast Cancer: 197 people, 12.57%
  4. Osteoporosis (bones weak and more likely to break): 170 people, 10.85%
  5. Depression: 125 people, 7.98%

Click here to view more results or personalize the results to your gender and age

Top co-used drugs for these people *:

  1. Zometa: 1,374 people, 87.68%
  2. Aredia: 1,071 people, 68.35%
  3. Lasix: 512 people, 32.67%
  4. Decadron: 454 people, 28.97%
  5. Prilosec: 441 people, 28.14%

Click here to view more results or personalize the results to your gender and age

Top other side effects for these people *:

  1. Pain: 1,225 people, 78.17%
  2. Stress And Anxiety: 1,116 people, 71.22%
  3. Anaemia (lack of blood): 803 people, 51.24%
  4. Breathing Difficulty: 761 people, 48.56%
  5. Osteomyelitis (infection of bone): 747 people, 47.67%

Click here to view more results or personalize the results to your gender and age

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study



Do you have Osteonecrosis of jaw while taking Coumadin?


You are not alone:




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