Creon and Pre-existing condition improved - a phase IV clinical study of FDA data
Summary:
We study 27,003 people who have side effects when taking Creon. Pre-existing condition improved is found, especially among people who are female, 60+ old, have been taking the drug for 1 - 2 years, also take Xyrem and have Narcolepsy.
The phase IV clinical study analyzes which people take Creon and have Pre-existing condition improved. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
27,003 people reported to have side effects when taking Creon.
Among them, 21 people (0.08%) have Pre-existing condition improved.
What is Creon?
Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is used in pancreatitis. Currently, eHealthMe is studying from 27,262 Creon users.
What is Pre-existing condition improved?
Pre-existing condition improved is found to be associated with 1,179 drugs and 548 conditions by eHealthMe. Currently, we are studying 8,308 people who have Pre-existing condition improved.
Number of Creon and Pre-existing condition improved reports submitted per year:

Time on Creon when people have Pre-existing condition improved *:
- < 1 month: 0.0 %
- 1 - 6 months: 25 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 50 %
- 2 - 5 years: 25 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Pre-existing condition improved when taking Creon *:
- female: 76.19 %
- male: 23.81 %
Age of people who have Pre-existing condition improved when taking Creon *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 10 %
- 30-39: 10 %
- 40-49: 10 %
- 50-59: 20 %
- 60+: 50 %
Common drugs people take besides Creon *:
- Xyrem: 16 people, 76.19%
- Lyrica: 11 people, 52.38%
- Ativan: 8 people, 38.10%
- Nexium: 7 people, 33.33%
- Cymbalta: 6 people, 28.57%
- Ondansetron: 6 people, 28.57%
- Vitamin D3: 5 people, 23.81%
- Synthroid: 5 people, 23.81%
- Norco: 5 people, 23.81%
- Zetia: 5 people, 23.81%
Common side effects people have besides Pre-existing condition improved *:
- Therapeutic Response Unexpected: 17 people, 80.95%
- Memory Loss: 5 people, 23.81%
- Weight Decreased: 5 people, 23.81%
- Feeling Abnormal: 5 people, 23.81%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 19.05%
- Sinusitis (inflammation of sinus): 3 people, 14.29%
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 14.29%
- Laryngitis (inflammation of the larynx): 3 people, 14.29%
- Ankle Fracture: 3 people, 14.29%
- Visual Impairment: 3 people, 14.29%
Common conditions people have *:
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 66.67%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 38.10%
- Pain: 4 people, 19.05%
- Neuropathy Peripheral (surface nerve damage): 4 people, 19.05%
- Nausea (feeling of having an urge to vomit): 4 people, 19.05%
- Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 4 people, 19.05%
- Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 14.29%
- Diabetes: 3 people, 14.29%
- Sleep Disorder: 2 people, 9.52%
- Drowsiness: 2 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Creon and have Pre-existing condition improved?
Check whether Pre-existing condition improved is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Creon side effects by duration, gender and age:
- Creon side effects (27,262 reports)
Pre-existing condition improved treatments and more:
- Pre-existing condition improved (8,308 reports)
Common drugs associated with Pre-existing condition improved:
- Xyrem: 3,395 reports
- Lyrica: 1,444 reports
- Adderall: 996 reports
- Gabapentin: 748 reports
- Vitamin d: 739 reports
- Nuvigil: 732 reports
- Cymbalta: 594 reports
- Omeprazole: 568 reports
- Xeljanz: 568 reports
- Modafinil: 519 reports
All the drugs that are associated with Pre-existing condition improved:
- Pre-existing condition improved (1,179 drugs)
Common conditions associated with Pre-existing condition improved:
- Narcolepsy: 2,912 reports
- Pain: 539 reports
- Rheumatoid arthritis: 487 reports
- Fibromyalgia: 469 reports
- Depression: 334 reports
- High blood pressure: 313 reports
- Stress and anxiety: 303 reports
- Sleep disorder: 241 reports
All the conditions that are associated with Pre-existing condition improved:
- Pre-existing condition improved (548 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) (the active ingredients of Creon) and Creon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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