Crestor and Renal tubular necrosis - a phase IV clinical study of FDA data

Summary:

We study 139,634 people who have side effects when taking Crestor. Renal tubular necrosis is found, especially among people who are male, 60+ old, have been taking the drug for 1 - 2 years, also take Nexium and have Gastroesophageal reflux disease.

The phase IV clinical study analyzes which people take Crestor and have Renal tubular necrosis. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

139,634 people reported to have side effects when taking Crestor.
Among them, 236 people (0.17%) have Renal tubular necrosis.

What is Crestor?

Crestor has active ingredients of rosuvastatin calcium. It is used in high blood cholesterol. Currently, eHealthMe is studying from 145,887 Crestor users.

What is Renal tubular necrosis?

Renal tubular necrosis (death of kidney tubules) is found to be associated with 1,691 drugs and 931 conditions by eHealthMe. Currently, we are studying 12,483 people who have Renal tubular necrosis.

Number of Crestor and Renal tubular necrosis reports submitted per year:

Could Crestor cause Renal tubular necrosis?

* Approximation only. Some reports may have incomplete information.

Do you take Crestor and have Renal tubular necrosis?

Check whether Renal tubular necrosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Crestor side effects by duration, gender and age:

Crestor side effects (145,887 reports)

Renal tubular necrosis treatments and more:

Renal tubular necrosis (12,483 reports)

Common drugs associated with Renal tubular necrosis:

All the drugs that are associated with Renal tubular necrosis:

Renal tubular necrosis (1,691 drugs)

Common conditions associated with Renal tubular necrosis:

High blood pressure: 1,002 reports
High blood cholesterol: 787 reports
Gastroesophageal reflux disease: 618 reports
Kidney transplant: 588 reports
Pain: 581 reports

All the conditions that are associated with Renal tubular necrosis:

Renal tubular necrosis (931 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rosuvastatin calcium (the active ingredients of Crestor) and Crestor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.