Cyclophosphamide and Blood calcium increased - a phase IV clinical study of FDA data


We study 169,775 people who have side effects when taking Cyclophosphamide. Blood calcium increased is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Dexamethasone and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people take Cyclophosphamide and have Blood calcium increased. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

169,775 people reported to have side effects when taking Cyclophosphamide.
Among them, 57 people (0.03%) have Blood calcium increased.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is used in multiple myeloma. Currently, eHealthMe is studying from 169,918 Cyclophosphamide users.

What is Blood calcium increased?

Blood calcium increased is found to be associated with 1,527 drugs and 804 conditions by eHealthMe. Currently, we are studying 10,286 people who have Blood calcium increased.

Number of Cyclophosphamide and Blood calcium increased reports submitted per year:

Could Cyclophosphamide cause Blood calcium increased?

Time on Cyclophosphamide when people have Blood calcium increased *:

  • < 1 month: 81.25 %
  • 1 - 6 months: 12.5 %
  • 6 - 12 months: 6.25 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Blood calcium increased when taking Cyclophosphamide *:

  • female: 54.55 %
  • male: 45.45 %

Age of people who have Blood calcium increased when taking Cyclophosphamide *:

  • 0-1: 0.0 %
  • 2-9: 3.92 %
  • 10-19: 1.96 %
  • 20-29: 0.0 %
  • 30-39: 27.45 %
  • 40-49: 7.84 %
  • 50-59: 7.84 %
  • 60+: 50.98 %

Common drugs people take besides Cyclophosphamide *:

  1. Dexamethasone: 24 people, 42.11%
  2. Prednisone: 14 people, 24.56%
  3. Cisplatin: 13 people, 22.81%
  4. Allopurinol: 12 people, 21.05%
  5. Cytarabine: 12 people, 21.05%
  6. Pantoprazole Sodium: 11 people, 19.30%
  7. Metformin Hydrochloride: 10 people, 17.54%
  8. Valsartan: 10 people, 17.54%
  9. Lactulose: 10 people, 17.54%
  10. Simvastatin: 10 people, 17.54%

Common side effects people have besides Blood calcium increased *:

  1. Blood Lactate Dehydrogenase Increased: 31 people, 54.39%
  2. Thrombocytopenia (decrease of platelets in blood): 20 people, 35.09%
  3. Splenomegaly (enlargement of spleen): 16 people, 28.07%
  4. Blood Uric Acid Increased: 15 people, 26.32%
  5. Tumor Lysis Syndrome: 14 people, 24.56%
  6. Encephalopathy (functioning of the brain is affected by some agent or condition): 14 people, 24.56%
  7. Blood Glucose Increased: 14 people, 24.56%
  8. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 13 people, 22.81%
  9. Gamma-Glutamyltransferase Increased: 13 people, 22.81%
  10. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 12 people, 21.05%

Common conditions people have *:

  1. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 12 people, 21.05%
  2. Diabetes: 8 people, 14.04%
  3. Disease Recurrence: 7 people, 12.28%
  4. Anaplastic Large Cell Lymphoma T- And Null-Cell Types Refractory (refractory -t-cell or null-cell cancer, a type of blood cancer): 5 people, 8.77%
  5. Breast Cancer: 3 people, 5.26%
  6. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 2 people, 3.51%
  7. Neoplasm Recurrence (reoccurrence of tumour): 2 people, 3.51%
  8. Breast Cancer Metastatic: 2 people, 3.51%
  9. High Blood Cholesterol: 2 people, 3.51%
  10. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 1.75%

* Approximation only. Some reports may have incomplete information.

Do you take Cyclophosphamide and have Blood calcium increased?

Check whether Blood calcium increased is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Cyclophosphamide side effects by duration, gender and age:

Blood calcium increased treatments and more:

Common drugs associated with Blood calcium increased:

All the drugs that are associated with Blood calcium increased:

Common conditions associated with Blood calcium increased:

All the conditions that are associated with Blood calcium increased:

How the study uses the data?

The study uses data from the FDA. It is based on cyclophosphamide (the active ingredients of Cyclophosphamide) and Cyclophosphamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: