Cyclophosphamide and Dupuytren's contracture - a phase IV clinical study of FDA data

• Cyclophosphamide (132,174 reports)

• Abdominal abscess (collection of pus in abdomen): 120 reports
• Abdominal discomfort: 275 reports
• Abdominal distension: 426 reports
• Abdominal pain: 1,941 reports
• Abdominal pain lower: 109 reports
• Abdominal pain upper: 610 reports
• Abscess (pus): 244 reports
• Acidosis (build-up of carbon dioxide in the blood): 134 reports
• Activated partial thromboplastin time prolonged: 122 reports
• Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 170 reports
• Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant): 1,268 reports
• Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant): 284 reports
• Acute graft versus host disease in liver (acute complication in liver following an allogeneic tissue/blood transplant): 148 reports
• Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant): 650 reports
• Acute hepatic failure: 332 reports
• Acute kidney failure: 1,817 reports
• Acute leukaemia (blood cancer): 124 reports
• Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 404 reports
• Acute lymphocytic leukemia (all) (cancer of the white blood cells characterized by excess lymphoblasts): 368 reports
• Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1,996 reports
• Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent): 120 reports
• Acute myocardial infarction (acute heart attack): 322 reports
• Acute promyelocytic leukaemia (cancer of the blood and bone marrow): 195 reports
• Acute pulmonary oedema (sudden deposit of fluid in the lung)): 163 reports
• Acute respiratory failure: 335 reports
• Adenovirus infection: 473 reports
• Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids): 102 reports
• Adverse drug reaction: 150 reports
• Adverse event: 267 reports
• Agitation (state of anxiety or nervous excitement): 319 reports
• Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 9,698 reports
• Alanine aminotransferase increased: 1,287 reports
• Altered state of consciousness (altered state of mind): 202 reports
• Anaemia (lack of blood): 4,714 reports
• Anaemia haemolytic autoimmune (condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells): 110 reports
• Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 441 reports
• Angioedema (rapid swelling of the dermis): 101 reports
• Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 278 reports
• Anuria (failure of the kidneys to produce urine): 135 reports
• Aplastic anemia: 206 reports
• Appendicitis (inflammation of the appendix): 123 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 1,429 reports
• Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system): 1,029 reports
• Arrhythmias (irregular heartbeat): 1,654 reports
• Arthritis (form of joint disorder that involves inflammation of one or more joints): 203 reports
• Arthropathy: 114 reports
• Ascites (accumulation of fluid in the abdominal cavity): 923 reports
• Aseptic necrosis (the death of bone tissue due to a lack of blood supply): 831 reports
• Aspartate aminotransferase increased: 1,078 reports
• Aspergillosis (an infection caused by a fungus called aspergillus): 220 reports
• Asthma: 266 reports
• Atelectasis (partial or complete collapse of the lung): 381 reports
• Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1,610 reports
• Back pain: 1,151 reports
• Bacteraemia (presence of bacteria in the blood): 635 reports
• Bacterial infection: 758 reports
• Bacterial sepsis: 340 reports
• Balance disorder: 178 reports
• Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills): 241 reports
• B-cell lymphoma recurrent (blood cancer affecting b cells-recurrent): 204 reports
• B-cell type acute leukaemia (cancer of the white blood cells): 228 reports
• Bk virus infection: 465 reports
• Bladder cancer: 105 reports
• Bleeding disorders: 369 reports
• Bleeding into the skin: 159 reports
• Blindness: 318 reports
• Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 264 reports
• Blood albumin decreased: 171 reports
• Blood alkaline phosphatase increased: 376 reports
• Blood bilirubin increased: 840 reports
• Blood creatine phosphokinase increased: 152 reports
• Blood creatinine increased: 938 reports
• Blood culture positive: 283 reports
• Blood disorder: 120 reports
• Blood glucose increased: 250 reports
• Blood lactate dehydrogenase increased: 721 reports
• Blood magnesium decreased: 105 reports
• Blood potassium decreased: 245 reports
• Blood sodium decreased: 183 reports
• Blood urea increased: 248 reports
• Body temperature increased: 317 reports
• Bone disorder: 255 reports
• Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries): 161 reports
• Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells): 237 reports
• Bone marrow disorder: 139 reports
• Bone marrow failure: 2,033 reports
• Bone marrow toxicity (decrease in cells responsible for providing immunity, carrying oxygen, and those responsible for normal blood clotting): 189 reports
• Bone pain: 1,005 reports
• Bradycardia (abnormally slow heart action): 364 reports
• Brain abscess: 119 reports
• Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 260 reports
• Breast cancer: 456 reports
• Breast cancer metastatic: 259 reports
• Breast cancer recurrent: 155 reports
• Breathing difficulty: 3,551 reports
• Breathing - slowed or stopped: 120 reports
• Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 145 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 412 reports
• Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi): 828 reports
• Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 117 reports
• Burkitt lymphoma (cancer of the lymphatic system): 335 reports
• Burkitt's lymphoma (cancer of the lymphatic system): 124 reports
• Burning sensation: 153 reports
• Cachexia (loss of weight): 122 reports
• Caecitis (inflammation of the cecum): 141 reports
• Candidiasis (candidiasis or thrush is a fungal infection): 235 reports
• Capillary leak syndrome (capillary leaks plasma): 210 reports
• Cardiac arrest: 888 reports
• Cardiac disorder: 444 reports
• Cardiac failure: 1,665 reports
• Cardiac failure acute: 128 reports
• Cardiac failure congestive: 876 reports
• Cardiogenic shock (inadequate circulation of blood): 149 reports
• Cardiomyopathy (weakening of the heart muscle): 846 reports
• Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 404 reports
• Cardiotoxicity (damage to the heart muscle): 834 reports
• Cataract (clouding of the lens inside the eye): 219 reports
• Cellulitis (infection under the skin): 817 reports
• Central nervous system lesion (an abnormality in tissue of brain or spinal cord): 129 reports
• Central nervous system lymphoma (cancer of central nervous system forms in lymph tissue): 147 reports
• Cerebral haemorrhage (bleeding within the brain): 457 reports
• Cerebral infarction (less blood supply to brain resulting tissue damage): 322 reports
• Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand): 128 reports
• Cerebral toxoplasmosis (parasitic disease of brain caused by the protozoan toxoplasma gondii): 112 reports
• Chest pain: 1,483 reports
• Chills (felling of cold): 1,286 reports
• Cholecystitis (infection of gallbladder): 215 reports
• Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 306 reports
• Chronic graft versus host disease (immune cells attack the host's body cells after transplant): 834 reports
• Chronic graft versus host disease in skin (damage by immune cells to skin after grafting): 114 reports
• Chronic kidney disease: 192 reports
• Chronic lymphocytic leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 262 reports
• Chronic lymphocytic leukaemia recurrent (repeated cancer of blood cells known as lymphocytes): 111 reports
• Chronic myeloid leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 157 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 198 reports
• Circulatory collapse: 255 reports
• Clostridial infection (infectious conditions by clostridium bacteria): 142 reports
• Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection): 637 reports
• Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 339 reports
• Colitis (inflammation of colon): 765 reports
• Colon cancer: 141 reports
• Confusion: 324 reports
• Confusional state: 1,089 reports
• Congestive cardiomyopathy (weakening of heart muscle): 214 reports
• Conjunctivitis (pink eye): 130 reports
• Consciousness - decreased: 397 reports
• Constipation: 1,451 reports
• Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 590 reports
• Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly): 116 reports
• Coronary heart disease (narrowing or blockage of the coronary arteries): 123 reports
• Corona virus infection (infection caused by a corona virus): 126 reports
• Cough: 1,787 reports
• Coughing up blood: 264 reports
• C-reactive protein increased: 646 reports
• Cushingoid (obesity and weakening of the muscles): 109 reports
• Cystitis haemorrhagic (blood in the urine and painful voiding): 985 reports
• Cytogenetic abnormality: 120 reports
• Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 2,244 reports
• Cytomegalovirus chorioretinitis (infection of choroid and retina of the eye from virus): 397 reports
• Cytomegalovirus colitis (an inflammation of the colon from virus): 122 reports
• Cytomegalovirus infection: 2,166 reports
• Cytomegalovirus test positive: 206 reports
• Cytomegalovirus viraemia (cytomegalo virus in blood stream): 498 reports
• Death: 3,932 reports
• Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1,150 reports
• Deformity (disfigurement): 141 reports
• Dehydration (dryness resulting from the removal of water): 1,512 reports
• Delirium (wild excitement): 271 reports
• Dental caries: 131 reports
• Depressed level of consciousness: 601 reports
• Depression: 752 reports
• Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 207 reports
• Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss): 113 reports
• Device related infection: 543 reports
• Diabetes: 464 reports
• Diarrhea: 4,594 reports
• Diffuse alveolar damage (common manifestation of drug-induced lung injury): 165 reports
• Diffuse interstitial lung disease (group of lung diseases affecting the interstitium): 103 reports
• Diffuse large b-cell lymphoma recurrent (recurrent cancer of b cells, a type of white blood cell): 554 reports
• Diffuse large b-cell lymphoma refractory (cancer of b cells, a type of white blood cell-relapsed): 166 reports
• Diplopia (double vision): 182 reports
• Discomfort: 130 reports
• Disease progression: 2,776 reports
• Disease recurrence: 1,225 reports
• Disseminated intravascular coagulation (systemic activation of blood coagulation): 697 reports
• Disturbance in attention: 176 reports
• Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 209 reports
• Dizziness: 1,345 reports
• Drowsiness: 575 reports
• Drug effect decreased: 140 reports
• Drug eruption (adverse drug reaction of the skin): 122 reports
• Drug exposure during pregnancy: 376 reports
• Drug hypersensitivity: 552 reports
• Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications): 166 reports
• Drug ineffective: 4,764 reports
• Drug intolerance (drug sensitivity): 641 reports
• Drug level increased: 127 reports
• Drug resistance (reduction in effectiveness of a drug): 786 reports
• Drug toxicity: 560 reports
• Dry mouth: 135 reports
• Dry skin: 145 reports
• Dyspnea exertional: 389 reports
• Ear pain: 110 reports
• Ejection fraction decreased (systolic heart failure): 845 reports
• Electrocardiogram qt prolonged: 219 reports
• Electrolyte imbalance: 210 reports
• Embolism (obstruction of an artery, typically by a clot of blood or an air bubble): 359 reports
• Emotional distress: 478 reports
• Encephalitis (inflammation of the brain): 328 reports
• Encephalitis viral (inflammation of the brain due to viral infection): 103 reports
• Encephalopathy (functioning of the brain is affected by some agent or condition): 849 reports
• Endocarditis (inflammation in heart muscle): 140 reports
• Engraftment syndrome (inflammatory condition during neutrophil recovery after hematopoietic stem cell transplantation): 187 reports
• Enlarged heart: 217 reports
• Enteritis (inflammation of the small intestine): 250 reports
• Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae): 199 reports
• Enterococcal bacteraemia (presence of bacteria lactic acid in the blood): 113 reports
• Enterococcal infection: 386 reports
• Enterococcal sepsis: 116 reports
• Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 164 reports
• Eosinophilia (eosinophil count in the peripheral blood exceeds): 112 reports
• Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 232 reports
• Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus): 289 reports
• Epstein-barr virus infection: 666 reports
• Erysipelas (bacterial skin infection): 118 reports
• Erythema multiforme (a type of hypersensitivity reaction): 480 reports
• Escherichia bacteraemia (presence of bacteria escherichia coli in the blood): 174 reports
• Escherichia infection (bacterial infection by escherichia coli): 324 reports
• Escherichia sepsis (bacterial infection by escherichia coli): 223 reports
• Escherichia urinary tract infection (urinary tract infection by escherichia coli): 144 reports
• Extravasation (leakage of a fluid): 101 reports
• Eye pain: 111 reports
• Face oedema (swelling of face): 111 reports
• Failure to thrive (inadequate weight gain and physical growth in children): 127 reports
• Fainting (loss of consciousness and postural tone): 939 reports
• Fall: 888 reports
• Fatigue (feeling of tiredness): 4,000 reports
• Febrile bone marrow aplasia (bone marrow greatly decreases or stops production of blood cells): 725 reports
• Febrile neutropenia (fever with reduced white blood cells): 11,472 reports
• Feeling hot: 113 reports
• Fever: 8,995 reports
• Fluid overload (too much fluid in the blood): 223 reports
• Fluid retention (an abnormal accumulation of fluid in the blood): 226 reports
• Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 478 reports
• Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy): 119 reports
• Full blood count decreased: 136 reports
• Fungaemia (fungi circulate in the blood): 134 reports
• Fungal infection: 787 reports
• Fusarium infection (fungal infection): 122 reports
• Gait disturbance: 424 reports
• Gallstones (stone formation by bile component): 180 reports
• Gamma-glutamyltransferase increased: 364 reports
• Gastric haemorrhage (bleeding stomach): 114 reports
• Gastric ulcer (stomach ulcer): 306 reports
• Gastritis (inflammation of stomach): 271 reports
• Gastroenteritis (inflammation of stomach and intestine): 240 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 319 reports
• Gastrointestinal disorder (functional problems of gastrointestinal tract): 663 reports
• Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 821 reports
• Gastrointestinal infection (infection of stomach and intestine): 138 reports
• Gastrointestinal inflammation (inflammation of stomach and intestine): 139 reports
• Gastrointestinal necrosis (destruction of gastrointestinal organ): 103 reports
• Gastrointestinal perforation (hole in the digestive tract): 433 reports
• Gastrointestinal toxicity (damage to digestive tract by any substance): 248 reports
• Generalised oedema (swelling all over the body): 218 reports
• General physical health deterioration (weak health status): 1,418 reports
• Gingivitis (inflammation of gums): 114 reports
• Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1,350 reports
• Graft versus host disease in skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 380 reports
• Grand mal convulsion (a type of generalized seizure that affects the entire brain): 164 reports
• Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system): 158 reports
• Haematemesis (vomiting of blood): 179 reports
• Haematochezia (passage of stools containing blood): 189 reports
• Haematocrit decreased: 1,042 reports
• Haematoma (collection of blood outside the blood vessels): 178 reports
• Haematotoxicity (toxins that destroy red blood cells): 1,108 reports
• Haematuria (presence of blood in urine): 630 reports
• Haemodynamic instability (disturbances in the blood movement in our body): 103 reports
• Haemoglobin decreased: 2,530 reports
• Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid): 174 reports
• Haemolytic anaemia (anaemia due to haemolysis): 256 reports
• Haemolytic uraemic syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 116 reports
• Haemorrhage (bleeding): 659 reports
• Haemorrhage intracranial (bleeding within the skull): 241 reports
• Haemorrhoids (a swollen vein or group of veins in the region of the anus): 167 reports
• Hair disorder: 555 reports
• Hair loss: 2,431 reports
• Hallucinations (sensations that appear real but are created by your mind): 176 reports
• Headache (pain in head): 2,245 reports
• Head injury: 297 reports
• Hearing loss: 242 reports
• Heart attack: 637 reports
• Heart disease: 172 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 315 reports
• Heart rate increased: 408 reports
• Hemiparesis (weakness on one side of the body): 391 reports
• Hemiplegia (paralysis of one side of the body): 102 reports
• Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 125 reports
• Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure): 182 reports
• Hepatic enzyme increased: 362 reports
• Hepatic failure (liver failure): 1,031 reports
• Hepatic necrosis (large portions of liver die off due to severe liver disease): 174 reports
• Hepatic steatosis (fatty liver disease): 251 reports
• Hepatitis (inflammation of the liver): 431 reports
• Hepatitis b: 1,021 reports
• Hepatitis c: 134 reports
• Hepatitis cholestatic (flow of bile from the liver is slowed or blocked): 106 reports
• Hepatitis fulminant (life-threatening condition defined by significantly impaired liver function): 134 reports
• Hepatocellular injury (liver injury): 227 reports
• Hepatomegaly (abnormal enlargement of the liver): 514 reports
• Hepatotoxicity (chemical-driven liver damage): 753 reports
• Herpes simplex (herpes simplex is a common viral infection): 420 reports
• Herpes virus infection: 140 reports
• Herpes zoster: 1,205 reports
• High blood cholesterol: 284 reports
• High blood pressure: 1,828 reports
• Histiocytosis haematophagic: 465 reports
• Hoarseness or changing voice: 130 reports
• Hodgkin's lymphoma (cancer originating from white blood cells): 236 reports
• Hospitalisation: 147 reports
• Hot flush (sudden feelings of heat): 174 reports
• Human herpesvirus 6 infection: 455 reports
• Hydrocephalus (water on the brain): 131 reports
• Hyperbilirubinaemia (excess of bilirubin in the blood): 403 reports
• Hypercalcaemia (elevated calcium (ca+) level in the blood): 242 reports
• Hyperglycemia (high blood sugar): 609 reports
• Hyperhidrosis (abnormally increased sweating): 365 reports
• Hyperkalemia (damage to or disease of the kidney): 416 reports
• Hyperlipidaemia (presence of excess lipids in the blood): 125 reports
• Hyperpyrexia (extremely high fever): 119 reports
• Hypersensitivity: 729 reports
• Hypertriglyceridaemia (excess of triglycerides in the blood): 206 reports
• Hyperuricaemia (level of uric acid in the blood that is abnormally high): 130 reports
• Hypoacusis (loss of hearing): 147 reports
• Hypoaesthesia (reduced sense of touch or sensation): 696 reports
• Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 290 reports
• Hypocalcaemia (levels of calcium in blood serum are abnormally low): 368 reports
• Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1,116 reports
• Hypoglycemia (low blood sugar): 158 reports
• Hypokalemia (low potassium): 1,123 reports
• Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 236 reports
• Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 903 reports
• Hypophagia (reduced food intake): 293 reports
• Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 225 reports
• Hypotension (abnormally low blood pressure): 3,441 reports
• Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 258 reports
• Hypovolaemia (a decreased volume of circulating blood in the body): 113 reports
• Idiopathic pulmonary fibrosis (chronic lung disease): 515 reports
• Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles): 237 reports
• Ill-defined disorder: 198 reports
• Immunodeficiency: 174 reports
• Immunodeficiency disorders: 204 reports
• Impaired healing: 213 reports
• Inappropriate antidiuretic hormone secretion: 215 reports
• Indigestion: 341 reports
• Infection: 3,707 reports
• Infection reactivation: 108 reports
• Inflammation: 471 reports
• Influenza like illness: 230 reports
• Infusion related reaction: 646 reports
• Injury: 191 reports
• Insomnia (sleeplessness): 589 reports
• International normalised ratio increased: 154 reports
• Interstitial lung disease: 1,737 reports
• Interstitial nephritis (inflammation of the kidney): 124 reports
• Intervertebral disc protrusion (spinal disc protrusion): 147 reports
• Intestinal obstruction: 565 reports
• Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 109 reports
• Irritability: 116 reports
• Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain): 119 reports
• Itching: 712 reports
• Jaundice - yellow skin (a yellowish pigmentation of the skin): 318 reports
• Jc virus infection: 232 reports
• Joint pain: 1,309 reports
• Joint swelling: 247 reports
• Kaposi's sarcoma (a tumour caused by human herpes virus): 205 reports
• Kidney infection (pyelonephritis): 127 reports
• Kidney stones: 130 reports
• Klebsiella infection: 346 reports
• Klebsiella sepsis (klebsiella causes a potentially fatal whole-body inflammation): 105 reports
• Lacrimation increased: 147 reports
• Large intestine perforation (hole in large intestine): 118 reports
• Left ventricular dysfunction: 574 reports
• Left ventricular failure (left ventricle fails to contract forcefully): 132 reports
• Leukaemia (blood or bone marrow cancer): 166 reports
• Leukaemia recurrent (repeat cancer of bone marrow or blood cells): 214 reports
• Leukocytosis (increased white blood cells): 371 reports
• Leukoencephalopathy (disease of the white matter in the brain): 264 reports
• Leukopenia (less number of white blood cells in blood): 2,523 reports
• Lipase increased: 117 reports
• Liver disorder (liver diseases): 517 reports
• Liver injury: 180 reports
• Loss of consciousness: 565 reports
• Low birth weight baby: 125 reports
• Lower respiratory tract infection: 578 reports
• Low tissue oxygen: 650 reports
• Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces): 151 reports
• Lung disorder (lung disease): 737 reports
• Lung infection: 758 reports
• Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 705 reports
• Lung neoplasm (tumour of lung): 158 reports
• Lung neoplasm malignant (cancer tumour of lung): 195 reports
• Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 137 reports
• Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 983 reports
• Lymphocyte count decreased: 1,133 reports
• Lymphoedema (localized fluid retention and tissue swelling): 104 reports
• Lymphoma (cancer that begins in immune system cells): 483 reports
• Lymphopenia (an abnormally low level of lymphocytes in the blood): 1,018 reports
• Lymphoproliferative disorder (a medical condition in which the immune system makes too many white blood cells): 239 reports
• Malaise (a feeling of general discomfort or uneasiness): 1,507 reports
• Malignant melanoma (skin cancer rises from melancytes): 171 reports
• Malignant neoplasm progression (cancer tumour came back): 2,513 reports
• Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 201 reports
• Mantle cell lymphoma recurrent (cancer of lymphocytes, a type of white blood cell- recurrent): 106 reports
• Maternal exposure during pregnancy (use of substance during pregnancy): 474 reports
• Melaena (the passage of black, tarry stools): 220 reports
• Memory loss: 486 reports
• Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 144 reports
• Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 197 reports
• Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 403 reports
• Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 265 reports
• Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 129 reports
• Metastases to bone (cancer spreads to bone): 573 reports
• Metastases to central nervous system (cancer spreads to central nervous system): 317 reports
• Metastases to liver (cancer spreads to liver): 478 reports
• Metastases to lung (cancer spreads to lung): 359 reports
• Metastases to lymph nodes (cancer spreads to lymph node): 283 reports
• Metastasis (spreadable cancer to other organ from origin): 310 reports
• Migraine (headache): 134 reports
• Mitral valve incompetence (inefficient heart valve): 290 reports
• Mobility decreased (ability to move is reduced): 165 reports
• Mouth haemorrhage (bleeding from mouth): 109 reports
• Mouth ulcers: 275 reports
• Movement - uncoordinated: 243 reports
• Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina): 280 reports
• Mucosal inflammation (infection of mucous membrane): 2,822 reports
• Multi-organ failure (multisystem organ failure): 1,159 reports
• Multiple myeloma (cancer of the plasma cells): 1,428 reports
• Muscle aches (muscle pain): 858 reports
• Muscle spasms (muscle contraction): 361 reports
• Musculoskeletal chest pain (pain in chest muscle or nerve or bones): 132 reports
• Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 256 reports
• Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 221 reports
• Mycobacterium chelonae infection (bacterial infection): 182 reports
• Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2,122 reports
• Myelopathy (any neurologic deficit related to the spinal cord): 161 reports
• Myelosuppression (a decrease in the production of blood cells): 260 reports
• Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 197 reports
• Myocarditis (inflammation of heart muscle myocardium): 200 reports
• Myopathy (a muscular disease in which the muscle fibres do not function): 128 reports
• Myositis (inflammation of the muscles): 219 reports
• Nail disorder (disease of nail): 128 reports
• Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 164 reports
• Nasopharyngitis (inflammation of the nasopharynx): 299 reports
• Nausea (feeling of having an urge to vomit): 4,743 reports
• Nausea and vomiting: 4,020 reports
• Neck pain: 228 reports
• Necrosis (the death of body tissue): 171 reports
• Neoplasm malignant (cancer tumour): 389 reports
• Neoplasm progression (growth of tumour): 897 reports
• Neoplasm recurrence (reoccurrence of tumour): 219 reports
• Nephropathy toxic (damage to kidney due to toxins): 470 reports
• Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 197 reports
• Nervous system disorder (a general class of medical conditions affecting the nervous system): 434 reports
• Neuralgia (pain in one or more nerves): 178 reports
• Neurological symptom (symptoms of nervous system disease): 121 reports
• Neuropathy peripheral (surface nerve damage): 2,301 reports
• Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system): 1,413 reports
• Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition): 211 reports
• Neutropenic infection (infection with less neutrophil numbers in blood): 202 reports
• Neutropenic sepsis (whole body infection is caused by a condition in which the number of white blood cells (called neutrophils) in the blood is low. neutrophils help the body to fight infection): 1,191 reports
• Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 2,745 reports
• Neutrophil count increased (excess than normal number of neutrophil a type of blood cell): 245 reports
• Night sweats (sweating in night): 239 reports
• Nocardia infection (a bacterial infection that usually starts in the lungs. it may spread to other organ systems): 137 reports
• Nodule (a small rock or mineral cluster): 138 reports
• Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system): 1,289 reports
• Non-hodgkin's lymphoma recurrent (reoccurrence malignant (cancer) cells form in the lymph system): 185 reports
• Nosebleed (bleeding from nose): 673 reports
• Numbness and tingling (unusual prickling sensations): 106 reports
• Obliterative bronchiolitis (bronchiolar inflammation): 168 reports
• Obstructive airways disorder (a progressive disease that makes it hard to breathe): 140 reports
• Oedema (fluid collection in tissue): 736 reports
• Oedema peripheral (superficial swelling): 963 reports
• Oesophageal candidiasis (fungal infection of oesophagus): 257 reports
• Oesophagitis (inflammation of oesophagus): 311 reports
• Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight): 130 reports
• Oral candidiasis (fungal infection of mouth): 405 reports
• Oral disorder (mouth disease): 161 reports
• Oral herpes (viral infection of mouth): 219 reports
• Oral pain: 285 reports
• Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue): 180 reports
• Oropharyngeal pain: 485 reports
• Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 147 reports
• Osteoarthritis (a joint disease caused by cartilage loss in a joint): 156 reports
• Osteomyelitis (infection of bone): 348 reports
• Osteonecrosis of jaw (death of bone of jaw): 511 reports
• Osteopenia (a condition where bone mineral density is lower than normal): 120 reports
• Osteoporosis (bones weak and more likely to break): 383 reports
• Ovarian failure (ovary is not functioning): 127 reports
• Overdose: 162 reports
• Oxygen saturation decreased: 426 reports
• Pain: 2,120 reports
• Pain in extremity: 942 reports
• Pain in jaw: 289 reports
• Pain of skin: 103 reports
• Paleness (unusual lightness of skin colour): 172 reports
• Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome): 607 reports
• Pancreatitis (inflammation of pancreas): 423 reports
• Pancreatitis acute (sudden inflammation of pancreas): 259 reports
• Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 3,322 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 868 reports
• Parainfluenzae virus infection: 285 reports
• Paraparesis (partial paralysis of the lower limbs): 140 reports
• Paroxysmal supraventricular tachycardia: 170 reports
• Pathogen resistance: 162 reports
• Pathological fracture (broken bone caused by disease): 154 reports
• Pericardial effusion (fluid around the heart): 593 reports
• Pericarditis (inflammation of the pericardium): 188 reports
• Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years): 159 reports
• Peripheral neuropathy (damage to nerves of the peripheral nervous system): 108 reports
• Peripheral sensory neuropathy (damage to one or more of your peripheral nerves): 511 reports
• Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 293 reports
• Pharyngitis (inflammation of the pharynx, causing a sore throat): 150 reports
• Plasmacytoma (neoplasm of plasma cells (usually in bone marrow)): 163 reports
• Pleural effusion (water on the lungs): 2,156 reports
• Pleuritic pain: 128 reports
• Pneumatosis intestinalis (air or gas in an intestine): 227 reports
• Pneumocystis jiroveci pneumonia (fungal infection of the lungs): 527 reports
• Pneumomediastinum (air is present in the mediastinum): 117 reports
• Pneumonia: 7,306 reports
• Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 232 reports
• Pneumonia bacterial (pneumonia associated with bacterial infection): 261 reports
• Pneumonia cytomegaloviral (cmv pneumonia is caused by a member of a group of herpes-type viruses): 281 reports
• Pneumonia fungal: 222 reports
• Pneumonia klebsiella (pneumonia caused by bacteria klebsiella): 106 reports
• Pneumonia viral: 105 reports
• Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 318 reports
• Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 161 reports
• Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 498 reports
• Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss): 749 reports
• Post procedural complication: 125 reports
• Post transplant lymphoproliferative disorder: 470 reports
• Premature baby: 430 reports
• Premature delivery: 154 reports
• Premature menopause: 160 reports
• Presyncope: 128 reports
• Primary pulmonary hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 146 reports
• Proctalgia (pain in the rectum): 120 reports
• Productive cough: 400 reports
• Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells): 1,202 reports
• Prostate cancer: 200 reports
• Protein - urine: 444 reports
• Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas): 305 reports
• Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 497 reports
• Psychological trauma: 537 reports
• Psychotic disorder: 113 reports
• Pulmonary alveolar haemorrhage (acute bleeding): 256 reports
• Pulmonary congestion (congestion in the lungs): 127 reports
• Pulmonary embolism (blockage of the main artery of the lung): 1,758 reports
• Pulmonary haemorrhage (acute bleeding from the lung): 416 reports
• Pulmonary hypertension (increase in blood pressure in the lung artery): 336 reports
• Pulmonary mass: 199 reports
• Pulmonary mycosis (lung infection caused by yeast-like fungi): 108 reports
• Pulmonary oedema (fluid accumulation in the lungs): 779 reports
• Pulmonary toxicity (side effects on the lungs): 361 reports
• Pulmonary tuberculosis (lungs tuberculosis): 110 reports
• Purpura (purplish discoloration of the skin): 154 reports
• Rales (an abnormal respiratory sound characterized by fine crackles): 117 reports
• Rash erythematous (redness of the skin): 292 reports
• Rashes (redness): 3,045 reports
• Rash maculo-papular (red area on the skin that is covered with small confluent bumps): 250 reports
• Rash pruritic (redness with itching): 128 reports
• Rectal haemorrhage (bleeding from anus): 271 reports
• Recurrent cancer (repeated cancer): 149 reports
• Red blood cell count decreased: 281 reports
• Red blood cell sedimentation rate increased: 104 reports
• Refractory anaemia with an excess of blasts (one or more cell types are low in the blood and look abnormal in the bone marrow): 101 reports
• Renal disorder (kidney disease): 308 reports
• Renal failure acute (rapid kidney dysfunction): 883 reports
• Renal failure chronic (long lasting kidney dysfunction): 108 reports
• Renal impairment (severely reduced kidney function): 1,124 reports
• Renal tubular necrosis (death of kidney tubules): 130 reports
• Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 2,564 reports
• Respiratory disorder (respiratory disease): 420 reports
• Respiratory distress (difficulty in breathing): 750 reports
• Respiratory rate increased (excess breathing rate/min): 117 reports
• Respiratory syncytial virus infection (viral disease of respiratory system): 179 reports
• Respiratory tract infection: 453 reports
• Retinal haemorrhage (bleeding from retina): 145 reports
• Reversible posterior leukoencephalopathy syndrome (a brain disease with generalized seizures and headache): 131 reports
• Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 163 reports
• Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 192 reports
• Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 104 reports
• Rhinovirus infection: 303 reports
• Rib fracture: 140 reports
• Richter's syndrome (hairy cell cancer changes in fast growing b cell cancer tumour): 138 reports
• Secondary immunodeficiency (lack of immunity due to some disease): 240 reports
• Second primary malignancy (after getting cure a cancer, a new cancer development): 1,016 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 693 reports
• Sensory disturbance (sense disturbance): 152 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 5,038 reports
• Septic shock (shock due to blood infection): 2,250 reports
• Serum ferritin increased: 145 reports
• Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 303 reports
• Sinusitis (inflammation of sinus): 706 reports
• Sinusitis - chronic: 152 reports
• Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 340 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 219 reports
• Skin discoloration: 135 reports
• Skin disorder (skin disease): 181 reports
• Skin exfoliation (removal of the oldest dead skin cells): 264 reports
• Skin infection: 228 reports
• Skin mass: 106 reports
• Skin toxicity (skin damage due to toxin/poison): 238 reports
• Skin ulcer: 254 reports
• Sleep disorder: 168 reports
• Small intestinal obstruction (blockage in small intestine): 219 reports
• Speech disorder: 217 reports
• Speech impairment (adult) (inability to speak (adult)): 870 reports
• Spinal compression fracture (fracture due to spinal compression on bone): 124 reports
• Spinal fracture (fracture in one of vertebrae): 118 reports
• Spinal osteoarthritis (joint cartilage loss in spine): 108 reports
• Splenomegaly (enlargement of spleen): 387 reports
• Squamous cell carcinoma (a cancer of a kind of epithelial cell): 240 reports
• Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin): 116 reports
• Stable angina (a constant chest pain): 189 reports
• Staphylococcal bacteraemia (a bacterial infection of blood): 347 reports
• Staphylococcal infection (an infection with staphylococcus bacteria): 955 reports
• Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria): 430 reports
• Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 179 reports
• Stem cell transplant: 426 reports
• Stomatitis (inflammation of mucous membrane of mouth): 1,568 reports
• Streptococcal infection: 152 reports
• Stress and anxiety: 963 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 494 reports
• Strongyloidiasis (infection with strongyloides stercoralis): 102 reports
• Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain): 133 reports
• Subclavian vein thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein): 124 reports
• Subdural haematoma (blood collects between the skull and the surface of the brain): 156 reports
• Suicidal ideation: 133 reports
• Swallowing difficulty: 744 reports
• Swallowing pain or burning: 112 reports
• Swelling: 301 reports
• Swelling face: 226 reports
• Systemic candida (whole body fungal infection): 203 reports
• Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection): 151 reports
• Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 162 reports
• Systemic mycosis (fungal infections of the body): 168 reports
• Tachypnea: 276 reports
• Taste - impaired: 229 reports
• T-cell lymphoma (a blood cell cancer): 106 reports
• Tenderness (pain or discomfort when an affected area is touched): 142 reports
• The flu (the flu is caused by an influenza virus): 455 reports
• Therapeutic response decreased (less preventive response): 605 reports
• Thrombocytopenia (decrease of platelets in blood): 9,104 reports
• Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 165 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 646 reports
• Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 639 reports
• Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body): 140 reports
• Tinnitus (a ringing in the ears): 165 reports
• Tooth abscess (pus formation in tooth): 204 reports
• Toothaches (tooth pain): 109 reports
• Tooth disorder (tooth disease): 112 reports
• Tooth extraction: 166 reports
• Transaminases increased: 490 reports
• Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 157 reports
• Transplant failure (transplantation failed to meet outcome): 239 reports
• Transplant rejection (a transplant material is not worked): 194 reports
• Traumatic lung injury: 116 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 667 reports
• Tricuspid valve incompetence (inefficient heart valve): 167 reports
• Troponin increased: 111 reports
• Tuberculosis (a bacterial infection by mycobacterium tuberculosis): 152 reports
• Tumor: 376 reports
• Tumor lysis syndrome: 1,005 reports
• Unilateral hydronephrosis (kidney stone that causes obstruction of the ureter): 157 reports
• Unresponsive to stimuli: 171 reports
• Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding): 160 reports
• Upper respiratory tract infection: 632 reports
• Urinary incontinence (inability to control the flow of urine and involuntary urination): 196 reports
• Urinary retention (the inability to completely or partially empty the bladder): 289 reports
• Urinary tract infection: 1,469 reports
• Urination - painful: 250 reports
• Urine output decreased: 149 reports
• Urine output - decreased: 169 reports
• Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream): 143 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 310 reports
• Vasculitis (inflammation of a blood vessel or blood vessels): 347 reports
• Venoocclusive disease (small veins in the liver are obstructed): 682 reports
• Venoocclusive liver disease (small veins in the liver are obstructed): 1,045 reports
• Venous thrombosis (blood clot (thrombus) that forms within a vein): 246 reports
• Ventricular extrasystoles (premature cardiac contraction): 116 reports
• Ventricular fibrillation (abnormally irregular heart rhythm): 134 reports
• Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do): 202 reports
• Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 153 reports
• Viral haemorrhagic cystitis (lower urinary tract symptoms that include haematuria and irritative voiding symptoms): 146 reports
• Viral infection: 568 reports
• Vision blurred: 349 reports
• Visual acuity reduced (reduced clearness of vision): 232 reports
• Visual impairment: 345 reports
• Weakness: 3,136 reports
• Weight decreased: 1,348 reports
• Weight increased: 536 reports
• Weight loss: 165 reports
• Wheezing (a high-pitched whistling sound made while you breath): 213 reports
• White blood cell count decreased: 3,325 reports
• White blood cell count increased: 501 reports

• Dupuytren's contracture (2,031 reports)

All the drugs that are associated with Dupuytren's contracture:

• Dupuytren's contracture (445 drugs)

All the conditions that are associated with Dupuytren's contracture:

• Dupuytren's contracture (208 conditions)

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