Cyclophosphamide and Rhonchi - a phase IV clinical study of FDA data


We study 169,775 people who have side effects when taking Cyclophosphamide. Rhonchi is found, especially among people who are male, 60+ old, have been taking the drug for 1 - 6 months, also take Metformin and have Asthma.

The phase IV clinical study analyzes which people take Cyclophosphamide and have Rhonchi. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

What are phase IV trials?

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 24, 2023

169,775 people reported to have side effects when taking Cyclophosphamide.
Among them, 75 people (0.04%) have Rhonchi.

What is Cyclophosphamide?

Cyclophosphamide has active ingredients of cyclophosphamide. It is used in multiple myeloma. Currently, eHealthMe is studying from 169,918 Cyclophosphamide users.

What is Rhonchi?

Rhonchi (abnormal breath sounds) is found to be associated with 1,083 drugs and 456 conditions by eHealthMe. Currently, we are studying 2,340 people who have Rhonchi.

Number of Cyclophosphamide and Rhonchi reports submitted per year:

Could Cyclophosphamide cause Rhonchi?

Time on Cyclophosphamide when people have Rhonchi *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Rhonchi when taking Cyclophosphamide *:

  • female: 31.51 %
  • male: 68.49 %

Age of people who have Rhonchi when taking Cyclophosphamide *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.49 %
  • 20-29: 0.0 %
  • 30-39: 23.88 %
  • 40-49: 1.49 %
  • 50-59: 2.99 %
  • 60+: 70.15 %

Common drugs people take besides Cyclophosphamide *:

  1. Fosamax: 44 people, 58.67%
  2. Alvesco: 44 people, 58.67%
  3. Singulair: 44 people, 58.67%
  4. Synthroid: 44 people, 58.67%
  5. Metformin: 44 people, 58.67%
  6. Uniphyl: 43 people, 57.33%
  7. Breo Ellipta: 42 people, 56.00%
  8. Imuran: 36 people, 48.00%
  9. Spiriva: 36 people, 48.00%
  10. Prednisone: 31 people, 41.33%

Common side effects people have besides Rhonchi *:

  1. Breathing Difficulty: 67 people, 89.33%
  2. Cough: 65 people, 86.67%
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 65 people, 86.67%
  4. Wheezing (a high-pitched whistling sound made while you breath): 62 people, 82.67%
  5. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 62 people, 82.67%
  6. Haemophilus Infection (bacterial infection by haemophilus influenzae): 61 people, 81.33%
  7. Malaise (a feeling of general discomfort or uneasiness): 47 people, 62.67%
  8. Lung Infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 46 people, 61.33%
  9. Oropharyngeal Pain: 45 people, 60.00%
  10. Rhinorrhea (watery mucus discharge from the nose): 45 people, 60.00%

Common conditions people have *:

  1. Asthma: 44 people, 58.67%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 2.67%
  3. Nausea And Vomiting: 1 person, 1.33%
  4. Nausea (feeling of having an urge to vomit): 1 person, 1.33%
  5. Malignant Lymphoid Neoplasm (malignant growth or tumour caused by abnormal and uncontrolled cell division in lymph node): 1 person, 1.33%
  6. Malignant Histiocytosis (cancerous increase in the number of immune cells): 1 person, 1.33%
  7. High Density Lipoprotein Decreased: 1 person, 1.33%
  8. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 1 person, 1.33%
  9. Breast Cancer: 1 person, 1.33%

* Approximation only. Some reports may have incomplete information.

Do you take Cyclophosphamide and have Rhonchi?

Check whether Rhonchi is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Rhonchi and when was it recovered:

Expand to all the drugs that have ingredients of cyclophosphamide:

Alternative drugs to, pros and cons of Cyclophosphamide:

Browse all side effects of Cyclophosphamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Rhonchi treatments and more:

Common drugs associated with Rhonchi:

All the drugs that are associated with Rhonchi:

Common conditions associated with Rhonchi:

All the conditions that are associated with Rhonchi:

How the study uses the data?

The study uses data from the FDA. It is based on cyclophosphamide (the active ingredients of Cyclophosphamide) and Cyclophosphamide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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