Cyclosporine and Pneumatosis intestinalis - a phase IV clinical study of FDA data

Summary:

We study 52,892 people who have side effects when taking Cyclosporine. Pneumatosis intestinalis is found, especially among people who are male, 2-9 old, have been taking the drug for 1 - 6 months, also take Mycophenolate mofetil and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people take Cyclosporine and have Pneumatosis intestinalis. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

52,892 people reported to have side effects when taking Cyclosporine.
Among them, 112 people (0.21%) have Pneumatosis intestinalis.

What is Cyclosporine?

Cyclosporine has active ingredients of cyclosporine. It is used in psoriasis. Currently, eHealthMe is studying from 53,265 Cyclosporine users.

What is Pneumatosis intestinalis?

Pneumatosis intestinalis (air or gas in an intestine) is found to be associated with 713 drugs and 465 conditions by eHealthMe. Currently, we are studying 2,869 people who have Pneumatosis intestinalis.

Number of Cyclosporine and Pneumatosis intestinalis reports submitted per year:

Could Cyclosporine cause Pneumatosis intestinalis?

* Approximation only. Some reports may have incomplete information.

Do you take Cyclosporine and have Pneumatosis intestinalis?

Check whether Pneumatosis intestinalis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

Related studies

Cyclosporine side effects by duration, gender and age:

Cyclosporine side effects (53,265 reports)

Pneumatosis intestinalis treatments and more:

Pneumatosis intestinalis (2,869 reports)

Common drugs associated with Pneumatosis intestinalis:

All the drugs that are associated with Pneumatosis intestinalis:

Pneumatosis intestinalis (713 drugs)

Common conditions associated with Pneumatosis intestinalis:

Acute lymphocytic leukemia (all): 197 reports

All the conditions that are associated with Pneumatosis intestinalis:

Pneumatosis intestinalis (465 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Cyclosporine) and Cyclosporine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.