Cymbalta and Conversion disorder - a phase IV clinical study of FDA data


Conversion disorder is found among people who take Cymbalta, especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Cymbalta and have Conversion disorder. It is created by eHealthMe based on reports of 135,967 people who have side effects when taking Cymbalta from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 08, 2022

135,967 people reported to have side effects when taking Cymbalta.
Among them, 89 people (0.07%) have Conversion disorder.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 145,347 Cymbalta users for its effectiveness, alternative drugs and more.

What is Conversion disorder?

Conversion disorder (neurological symptoms, such as numbness, blindness, paralysis, or fits without a definable organic cause) is found to be associated with 902 drugs and 572 conditions by eHealthMe.

Number of Cymbalta and Conversion disorder reports submitted per year:

Could Cymbalta cause Conversion disorder?

Time on Cymbalta when people have Conversion disorder *:

  • < 1 month: 37.04 %
  • 1 - 6 months: 44.44 %
  • 6 - 12 months: 7.41 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 3.7 %
  • 5 - 10 years: 7.41 %
  • 10+ years: 0.0 %

Gender of people who have Conversion disorder when taking Cymbalta *:

  • female: 92.13 %
  • male: 7.87 %

Age of people who have Conversion disorder when taking Cymbalta *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 3.08 %
  • 20-29: 10.77 %
  • 30-39: 16.92 %
  • 40-49: 21.54 %
  • 50-59: 29.23 %
  • 60+: 18.46 %

Common drugs people take besides Cymbalta *:

  1. Klonopin: 10 people, 11.24%
  2. Ambien: 9 people, 10.11%
  3. Abilify: 8 people, 8.99%
  4. Neurontin: 8 people, 8.99%
  5. Topamax: 8 people, 8.99%
  6. Crestor: 7 people, 7.87%
  7. Synthroid: 6 people, 6.74%
  8. Provigil: 5 people, 5.62%
  9. Prozac: 5 people, 5.62%
  10. Ms Contin: 5 people, 5.62%

Common side effects people have besides Conversion disorder *:

  1. Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 17 people, 19.10%
  2. Insomnia (sleeplessness): 16 people, 17.98%
  3. Suicidal Ideation: 15 people, 16.85%
  4. Crying: 13 people, 14.61%
  5. Pain: 12 people, 13.48%
  6. Feeling Abnormal: 10 people, 11.24%
  7. Headache (pain in head): 10 people, 11.24%
  8. Tremor (trembling or shaking movements in one or more parts of your body): 10 people, 11.24%
  9. Nausea (feeling of having an urge to vomit): 9 people, 10.11%
  10. Muscle Spasms (muscle contraction): 9 people, 10.11%

Common conditions people have *:

  1. Pain: 6 people, 6.74%
  2. Sleep Apnea Syndrome: 4 people, 4.49%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 3.37%
  4. Post-Traumatic Stress Disorder: 3 people, 3.37%
  5. Neuralgia (pain in one or more nerves): 3 people, 3.37%
  6. Neuropathy Peripheral (surface nerve damage): 2 people, 2.25%
  7. Gastric Disorder (disease of stomach): 2 people, 2.25%
  8. Migraine (headache): 2 people, 2.25%
  9. Muscle Spasms (muscle contraction): 2 people, 2.25%
  10. Nausea (feeling of having an urge to vomit): 2 people, 2.25%

* Approximation only. Some reports may have incomplete information.

Do you take Cymbalta and have Conversion disorder?

Check whether Conversion disorder is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Conversion disorder and when was it recovered:

Expand to all the drugs that have ingredients of duloxetine hydrochloride:

Alternative drugs to, pros and cons of Cymbalta:

Common Cymbalta side effects:

Browse all side effects of Cymbalta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Conversion disorder treatments and more:

COVID vaccines that are related to Conversion disorder:

All the drugs that are associated with Conversion disorder:

Common conditions associated with Conversion disorder:

All the conditions that are associated with Conversion disorder:

How the study uses the data?

The study uses data from the FDA. It is based on duloxetine hydrochloride (the active ingredients of Cymbalta) and Cymbalta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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