Cymbalta and Sle arthritis - a phase IV clinical study of FDA data


We study 141,667 people who have side effects when taking Cymbalta. Sle arthritis is found, especially among people who are female, 60+ old, also take Benlysta and have Kidney stones.

The phase IV clinical study analyzes which people take Cymbalta and have Sle arthritis. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

141,667 people reported to have side effects when taking Cymbalta.
Among them, 15 people (0.01%) have Sle arthritis.

What is Cymbalta?

Cymbalta has active ingredients of duloxetine hydrochloride. It is used in depression. Currently, eHealthMe is studying from 151,241 Cymbalta users.

What is Sle arthritis?

Sle arthritis (an autoimmune disease that causes your immune system to attack your body's own joints) is found to be associated with 121 drugs and 52 conditions by eHealthMe. Currently, we are studying 510 people who have Sle arthritis.

Number of Cymbalta and Sle arthritis reports submitted per year:

Could Cymbalta cause Sle arthritis?

Gender of people who have Sle arthritis when taking Cymbalta *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Sle arthritis when taking Cymbalta *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Cymbalta *:

  1. Benlysta: 14 people, 93.33%
  2. Prednisone: 11 people, 73.33%
  3. Olmesartan Medoxomil: 11 people, 73.33%
  4. Clarithromycin: 11 people, 73.33%
  5. Accutane: 9 people, 60.00%
  6. Tylenol: 8 people, 53.33%
  7. Macrobid: 8 people, 53.33%
  8. Ciprofloxacin: 8 people, 53.33%
  9. Cipro: 7 people, 46.67%
  10. Acetaminophen: 6 people, 40.00%

Common side effects people have besides Sle arthritis *:

  1. Vein Disorder: 15 people, 100.00%
  2. Kidney Infection: 15 people, 100.00%
  3. Arthropathy: 15 people, 100.00%
  4. Calcinosis (calcium deposits in any soft tissue): 15 people, 100.00%
  5. Drowsiness: 15 people, 100.00%
  6. Drug Ineffective: 15 people, 100.00%
  7. Gait Disturbance: 15 people, 100.00%
  8. Hand Deformity: 15 people, 100.00%
  9. High Blood Pressure: 15 people, 100.00%
  10. Hypotension (abnormally low blood pressure): 15 people, 100.00%

Common conditions people have *:

  1. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 15 people, 100.00%
  2. Kidney Stones: 15 people, 100.00%
  3. Pain: 14 people, 93.33%
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints): 13 people, 86.67%
  5. Ear Discomfort: 9 people, 60.00%

* Approximation only. Some reports may have incomplete information.

Do you take Cymbalta and have Sle arthritis?

Check whether Sle arthritis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Cymbalta side effects by duration, gender and age:

Sle arthritis treatments and more:

Common drugs associated with Sle arthritis:

All the drugs that are associated with Sle arthritis:

Common conditions associated with Sle arthritis:

All the conditions that are associated with Sle arthritis:

How the study uses the data?

The study uses data from the FDA. It is based on duloxetine hydrochloride (the active ingredients of Cymbalta) and Cymbalta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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