Cytoxan and Nail ridging - a phase IV clinical study of FDA data


Nail ridging is reported only by a few people who take Cytoxan.

The phase IV clinical study analyzes which people take Cytoxan and have Nail ridging. It is created by eHealthMe based on reports of 18,852 people who have side effects while taking Cytoxan from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 02, 2023

18,852 people reported to have side effects when taking Cytoxan.
Among them, 2 people (0.01%) have Nail ridging.

What is Cytoxan?

Cytoxan has active ingredients of cyclophosphamide. It is often used in breast cancer. eHealthMe is studying from 19,020 Cytoxan users for its effectiveness, alternative drugs and more.

What is Nail ridging?

Nail ridging (nail has raised ridges and is thin and curved inward) is found to be associated with 422 drugs and 280 conditions by eHealthMe.

Number of Cytoxan and Nail ridging reports submitted per year:

Could Cytoxan cause Nail ridging?

Gender of people who have Nail ridging when taking Cytoxan *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Nail ridging when taking Cytoxan *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 100 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Common drugs people take besides Cytoxan *:

  1. Taxotere: 1 person, 50.00%
  2. Neulasta: 1 person, 50.00%
  3. Levaquin: 1 person, 50.00%
  4. Cipro: 1 person, 50.00%
  5. Avelox: 1 person, 50.00%

Common side effects people have besides Nail ridging *:

  1. Joint Pain: 2 people, 100.00%
  2. Hair Loss: 2 people, 100.00%
  3. Fatigue (feeling of tiredness): 2 people, 100.00%
  4. Weight Decreased: 1 person, 50.00%
  5. Eustachian Tube Obstruction (blockage of the eustachian tube): 1 person, 50.00%
  6. Hypoperfusion (decreased blood flow through an organ): 1 person, 50.00%
  7. Hypoaesthesia (reduced sense of touch or sensation): 1 person, 50.00%
  8. High Blood Pressure: 1 person, 50.00%
  9. Head Injury: 1 person, 50.00%
  10. Hair Color Changes: 1 person, 50.00%

Common conditions people have *:

  1. Sinusitis (inflammation of sinus): 1 person, 50.00%
  2. Otitis (ear infection): 1 person, 50.00%
  3. Immunodeficiency Disorders: 1 person, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Cytoxan and have Nail ridging?

Check whether Nail ridging is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Nail ridging and when was it recovered:

Expand to all the drugs that have ingredients of cyclophosphamide:

Alternative drugs to, pros and cons of Cytoxan:

Common Cytoxan side effects:

Browse all side effects of Cytoxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Nail ridging treatments and more:

COVID vaccines that are related to Nail ridging:

All the drugs that are associated with Nail ridging:

All the conditions that are associated with Nail ridging:

How the study uses the data?

The study uses data from the FDA. It is based on cyclophosphamide (the active ingredients of Cytoxan) and Cytoxan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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