Who have Osteonecrosis with Cytoxan - from FDA reports


Osteonecrosis is found among people who take Cytoxan, especially for people who are female, 50-59 old , have been taking the drug for 1 - 6 months, also take medication Zometa, and have Metastases to bone. This study is created by eHealthMe based on reports of 12,365 people who have side effects when taking Cytoxan from FDA, and is updated regularly.

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On Feb, 19, 2019

12,365 people reported to have side effects when taking Cytoxan.
Among them, 511 people (4.13%) have Osteonecrosis


Number of reports submitted per year:

Could Cytoxan cause Osteonecrosis?

Time on Cytoxan when people have Osteonecrosis *:

  • < 1 month: 12.5 %
  • 1 - 6 months: 74.17 %
  • 6 - 12 months: 8.33 %
  • 1 - 2 years: 3.33 %
  • 2 - 5 years: 1.67 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Osteonecrosis when taking Cytoxan *:

  • female: 76.41 %
  • male: 23.59 %

Age of people who have Osteonecrosis when taking Cytoxan *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.64 %
  • 20-29: 0.0 %
  • 30-39: 4.5 %
  • 40-49: 29.12 %
  • 50-59: 38.97 %
  • 60+: 26.77 %

Top conditions involved for these people *:

  1. Metastases To Bone (cancer spreads to bone): 132 people, 25.83%
  2. Pain: 71 people, 13.89%
  3. Breast Cancer Metastatic: 65 people, 12.72%
  4. Depression: 48 people, 9.39%
  5. Osteoporosis (bones weak and more likely to break): 45 people, 8.81%
  6. Anaemia (lack of blood): 34 people, 6.65%
  7. Stress And Anxiety: 32 people, 6.26%
  8. Chemotherapy: 28 people, 5.48%
  9. Preventive Health Care: 24 people, 4.70%
  10. High Blood Pressure: 24 people, 4.70%

Top co-used drugs for these people *:

  1. Zometa: 436 people, 85.32%
  2. Aredia: 343 people, 67.12%
  3. Adriamycin Pfs: 202 people, 39.53%
  4. Decadron: 136 people, 26.61%
  5. Prilosec: 128 people, 25.05%
  6. Prednisone: 127 people, 24.85%
  7. Dexamethasone: 119 people, 23.29%
  8. Arimidex: 114 people, 22.31%
  9. Oxycontin: 114 people, 22.31%
  10. Taxotere: 107 people, 20.94%

Top other side effects for these people *:

  1. Tooth Extraction: 313 people, 61.25%
  2. Bone Disorder: 305 people, 59.69%
  3. Pain: 292 people, 57.14%
  4. Stress And Anxiety: 225 people, 44.03%
  5. Osteomyelitis (infection of bone): 200 people, 39.14%
  6. Pain In Jaw: 187 people, 36.59%
  7. Injury: 186 people, 36.40%
  8. Infection: 152 people, 29.75%
  9. Anaemia (lack of blood): 148 people, 28.96%
  10. Impaired Healing: 135 people, 26.42%

* Approximation only. Some reports may have incomplete information.

Do you have Osteonecrosis while taking Cytoxan?


You are not alone:




Related studies

Cytoxan

Cytoxan has active ingredients of cyclophosphamide. It is often used in breast cancer. (latest outcomes from Cytoxan 12,520 users)

Osteonecrosis

Osteonecrosis (death of bone) has been reported by people with osteoporosis, metastases to bone, multiple myeloma, breast cancer, osteopenia (latest reports from 33,902 Osteonecrosis patients).


Drugs that are associated with Osteonecrosis
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Could your condition cause Osteonecrosis
Osteonecrosis (1,236 conditions)
Cytoxan side effects

Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Browse all side effects of Cytoxan
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Compare Cytoxan to similar drugs:

Related publications that referenced our studies


What would happen?

Predict new side effects and undetected conditions when you take Cytoxan and have Osteonecrosis


FDA reports used in this study



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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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