Darvocet and Unilateral hydronephrosis - a phase IV clinical study of FDA data


Unilateral hydronephrosis is found among people who take Darvocet, especially for people who are male, 40-49 old.

The phase IV clinical study analyzes which people take Darvocet and have Unilateral hydronephrosis. It is created by eHealthMe based on reports of 11,264 people who have side effects when taking Darvocet from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 01, 2022

11,264 people reported to have side effects when taking Darvocet.
Among them, 27 people (0.24%) have Unilateral hydronephrosis.

What is Darvocet?

Darvocet has active ingredients of acetaminophen; propoxyphene hydrochloride. It is often used in pain. eHealthMe is studying from 12,056 Darvocet users for its effectiveness, alternative drugs and more.

What is Unilateral hydronephrosis?

Unilateral hydronephrosis (kidney stone that causes obstruction of the ureter) is found to be associated with 1,729 drugs and 1,065 conditions by eHealthMe.

Number of Darvocet and Unilateral hydronephrosis reports submitted per year:

Could Darvocet cause Unilateral hydronephrosis?

Gender of people who have Unilateral hydronephrosis when taking Darvocet *:

  • female: 41.67 %
  • male: 58.33 %

Age of people who have Unilateral hydronephrosis when taking Darvocet *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 4.35 %
  • 30-39: 0.0 %
  • 40-49: 43.48 %
  • 50-59: 17.39 %
  • 60+: 34.78 %

Common drugs people take besides Darvocet *:

  1. Prilosec: 15 people, 55.56%
  2. Naproxen: 8 people, 29.63%
  3. Tylenol: 8 people, 29.63%
  4. Tysabri: 7 people, 25.93%
  5. Leucovorin Calcium: 7 people, 25.93%
  6. Temazepam: 7 people, 25.93%
  7. Concerta: 7 people, 25.93%
  8. Cymbalta: 7 people, 25.93%
  9. Nitroglycerin: 6 people, 22.22%
  10. Nexium: 6 people, 22.22%

Common side effects people have besides Unilateral hydronephrosis *:

  1. Anaemia (lack of blood): 12 people, 44.44%
  2. Diabetes: 11 people, 40.74%
  3. Urinary Tract Infection: 10 people, 37.04%
  4. Joint Pain: 10 people, 37.04%
  5. Thrombocytopenia (decrease of platelets in blood): 9 people, 33.33%
  6. Nausea (feeling of having an urge to vomit): 9 people, 33.33%
  7. Depression: 8 people, 29.63%
  8. Abdominal Pain: 7 people, 25.93%
  9. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 7 people, 25.93%
  10. Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 25.93%

Common conditions people have *:

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 25.93%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 11.11%
  3. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 11.11%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
  5. Stable Angina (a constant chest pain): 2 people, 7.41%
  6. Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 2 people, 7.41%
  7. Joint Pain: 2 people, 7.41%
  8. Multiple Myeloma (cancer of the plasma cells): 2 people, 7.41%
  9. Muscle Spasms (muscle contraction): 2 people, 7.41%
  10. Gout (uric acid crystals building up in the body): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Darvocet and have Unilateral hydronephrosis?

Check whether Unilateral hydronephrosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Unilateral hydronephrosis and when was it recovered:

Expand to all the drugs that have ingredients of acetaminophen; propoxyphene hydrochloride:

Alternative drugs to, pros and cons of Darvocet:

Common Darvocet side effects:

Browse all side effects of Darvocet:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Unilateral hydronephrosis treatments and more:

COVID vaccines that are related to Unilateral hydronephrosis:

Common drugs associated with Unilateral hydronephrosis:

All the drugs that are associated with Unilateral hydronephrosis:

Common conditions associated with Unilateral hydronephrosis:

All the conditions that are associated with Unilateral hydronephrosis:

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; propoxyphene hydrochloride (the active ingredients of Darvocet) and Darvocet (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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