Darzalex and Performance status decreased - a phase IV clinical study of FDA data

Summary:

We study 17,614 people who have side effects when taking Darzalex. Performance status decreased is found, especially among people who are male, 60+ old, have been taking the drug for 1 - 6 months, also take Dexamethasone and have Multiple myeloma.

The phase IV clinical study analyzes which people take Darzalex and have Performance status decreased. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 30, 2023

17,614 people reported to have side effects when taking Darzalex.
Among them, 9 people (0.05%) have Performance status decreased.

What is Darzalex?

Darzalex has active ingredients of daratumumab. Currently, eHealthMe is studying from 17,627 Darzalex users.

What is Performance status decreased?

Performance status decreased is found to be associated with 1,072 drugs and 600 conditions by eHealthMe. Currently, we are studying 5,125 people who have Performance status decreased.

Number of Darzalex and Performance status decreased reports submitted per year:

Could Darzalex cause Performance status decreased?

Time on Darzalex when people have Performance status decreased *:

Gender of people who have Performance status decreased when taking Darzalex *:

female: 20 %
male: 80 %

Age of people who have Performance status decreased when taking Darzalex *:

Common drugs people take besides Darzalex *:

Common side effects people have besides Performance status decreased *:

Lower Respiratory Tract Infection: 5 people, 55.56%
Hypocalcaemia (levels of calcium in blood serum are abnormally low): 4 people, 44.44%
Pneumonia: 3 people, 33.33%
Heart Attack: 3 people, 33.33%
Hyperglycemia (high blood sugar): 3 people, 33.33%
Hyperkalemia (damage to or disease of the kidney): 3 people, 33.33%
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs): 3 people, 33.33%
Anaemia (lack of blood): 3 people, 33.33%
Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 33.33%
Septic Shock (shock due to blood infection): 3 people, 33.33%

Common conditions people have *:

Multiple Myeloma (cancer of the plasma cells): 8 people, 88.89%

* Approximation only. Some reports may have incomplete information.

Do you take Darzalex and have Performance status decreased?

Check whether Performance status decreased is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Darzalex side effects by duration, gender and age:

Darzalex side effects (17,627 reports)

Performance status decreased treatments and more:

Performance status decreased (5,125 reports)

Common drugs associated with Performance status decreased:

How the study uses the data?

The study uses data from the FDA. It is based on daratumumab (the active ingredients of Darzalex) and Darzalex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.