Decadron and Lower gastrointestinal haemorrhage - a phase IV clinical study of FDA data
We study 46,101 people who have side effects when taking Decadron. Lower gastrointestinal haemorrhage is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Kytril and have Colon cancer.
The phase IV clinical study analyzes which people take Decadron and have Lower gastrointestinal haemorrhage. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
46,101 people reported to have side effects when taking Decadron.
Among them, 24 people (0.05%) have Lower gastrointestinal haemorrhage.
What is Decadron?
Decadron has active ingredients of dexamethasone. It is used in multiple myeloma. Currently, eHealthMe is studying from 46,472 Decadron users.
What is Lower gastrointestinal haemorrhage?
Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding) is found to be associated with 1,225 drugs and 569 conditions by eHealthMe. Currently, we are studying 9,013 people who have Lower gastrointestinal haemorrhage.
Number of Decadron and Lower gastrointestinal haemorrhage reports submitted per year:
Time on Decadron when people have Lower gastrointestinal haemorrhage *:
- < 1 month: 42.86 %
- 1 - 6 months: 28.57 %
- 6 - 12 months: 28.57 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
Gender of people who have Lower gastrointestinal haemorrhage when taking Decadron *:
- female: 52.38 %
- male: 47.62 %
Age of people who have Lower gastrointestinal haemorrhage when taking Decadron *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 4.76 %
- 40-49: 19.05 %
- 50-59: 4.76 %
- 60+: 71.43 %
Common drugs people take besides Decadron *:
- Kytril: 6 people, 25.00%
- Fluorouracil: 4 people, 16.67%
- Xarelto: 4 people, 16.67%
- Velcade: 3 people, 12.50%
- Minocycline Hydrochloride: 3 people, 12.50%
- Megace: 3 people, 12.50%
- Lansoprazole: 3 people, 12.50%
- Oxaliplatin: 3 people, 12.50%
- Omeprazole: 3 people, 12.50%
- Avastin: 3 people, 12.50%
Common side effects people have besides Lower gastrointestinal haemorrhage *:
- Rectal Haemorrhage (bleeding from anus): 5 people, 20.83%
- Thrombocytopenia (decrease of platelets in blood): 5 people, 20.83%
- Nausea (feeling of having an urge to vomit): 4 people, 16.67%
- Disease Progression: 4 people, 16.67%
- Itching: 3 people, 12.50%
- Constipation: 3 people, 12.50%
- Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 3 people, 12.50%
- Pain In Extremity: 3 people, 12.50%
- Dehydration (dryness resulting from the removal of water): 3 people, 12.50%
- Fatigue (feeling of tiredness): 3 people, 12.50%
Common conditions people have *:
- Colon Cancer: 4 people, 16.67%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 12.50%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 8.33%
- Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 2 people, 8.33%
- Prostate Cancer: 2 people, 8.33%
- Pain: 2 people, 8.33%
- Cancer Pain: 2 people, 8.33%
- Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 4.17%
- Chest Pain: 1 person, 4.17%
- Coagulation Factor V Level Decreased: 1 person, 4.17%
* Approximation only. Some reports may have incomplete information.
Do you take Decadron and have Lower gastrointestinal haemorrhage?Check whether Lower gastrointestinal haemorrhage is associated with a drug or a condition
How to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
Decadron side effects by duration, gender and age:
- Decadron side effects (46,472 reports)
Lower gastrointestinal haemorrhage treatments and more:
- Lower gastrointestinal haemorrhage (9,013 reports)
Common drugs associated with Lower gastrointestinal haemorrhage:
- Xarelto: 3,026 reports
- Aspirin: 1,746 reports
- Pradaxa: 1,491 reports
- Acetylsalicylic acid: 579 reports
- Lasix: 577 reports
- Furosemide: 541 reports
- Lisinopril: 521 reports
- Plavix: 434 reports
- Omeprazole: 392 reports
- Simvastatin: 364 reports
All the drugs that are associated with Lower gastrointestinal haemorrhage:
- Lower gastrointestinal haemorrhage (1,225 drugs)
Common conditions associated with Lower gastrointestinal haemorrhage:
- Atrial fibrillation/flutter: 3,669 reports
- Stroke: 2,195 reports
- Deep venous thrombosis: 665 reports
- High blood pressure: 525 reports
- Pulmonary embolism: 422 reports
- Pain: 337 reports
All the conditions that are associated with Lower gastrointestinal haemorrhage:
- Lower gastrointestinal haemorrhage (569 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on dexamethasone (the active ingredients of Decadron) and Decadron (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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