Demadex and Blood creatine increased - a phase IV clinical study of FDA data


Blood creatine increased is found among people who take Demadex, especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months.

The phase IV clinical study analyzes which people take Demadex and have Blood creatine increased. It is created by eHealthMe based on reports of 5,104 people who have side effects when taking Demadex from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 22, 2022

5,104 people reported to have side effects when taking Demadex.
Among them, 15 people (0.29%) have Blood creatine increased.

What is Demadex?

Demadex has active ingredients of torsemide. It is often used in heart failure. eHealthMe is studying from 5,144 Demadex users for its effectiveness, alternative drugs and more.

What is Blood creatine increased?

Blood creatine increased is found to be associated with 1,244 drugs and 617 conditions by eHealthMe.

Number of Demadex and Blood creatine increased reports submitted per year:

Could Demadex cause Blood creatine increased?

Time on Demadex when people have Blood creatine increased *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Blood creatine increased when taking Demadex *:

  • female: 80 %
  • male: 20 %

Age of people who have Blood creatine increased when taking Demadex *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 6.67 %
  • 50-59: 13.33 %
  • 60+: 80.0 %

Common drugs people take besides Demadex *:

  1. Coreg: 8 people, 53.33%
  2. Protonix: 6 people, 40.00%
  3. Tylenol: 5 people, 33.33%
  4. Aspirin: 5 people, 33.33%
  5. Naproxen: 5 people, 33.33%
  6. Ranexa: 5 people, 33.33%
  7. Reclast: 5 people, 33.33%
  8. Nitro-Dur: 5 people, 33.33%
  9. Lipitor: 5 people, 33.33%
  10. Digoxin: 3 people, 20.00%

Common side effects people have besides Blood creatine increased *:

  1. Blood Urea Increased: 11 people, 73.33%
  2. Weakness: 6 people, 40.00%
  3. Vitamin B12 Deficiency: 6 people, 40.00%
  4. Malaise (a feeling of general discomfort or uneasiness): 6 people, 40.00%
  5. Oedema (fluid collection in tissue): 6 people, 40.00%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 40.00%
  7. High Blood Pressure: 6 people, 40.00%
  8. Renal Failure Acute (rapid kidney dysfunction): 6 people, 40.00%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 33.33%
  10. Glomerular Filtration Rate Decreased: 5 people, 33.33%

Common conditions people have *:

  1. Osteopenia (a condition where bone mineral density is lower than normal): 4 people, 26.67%
  2. Ventricular Dysfunction (heart dysfunction): 1 person, 6.67%
  3. Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 6.67%
  4. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 1 person, 6.67%
  5. Hiv Infection: 1 person, 6.67%
  6. Chronic Myeloid Leukaemia (In Remission): 1 person, 6.67%
  7. Cardiac Failure Congestive: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Demadex and have Blood creatine increased?

Check whether Blood creatine increased is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Blood creatine increased and when was it recovered:

Expand to all the drugs that have ingredients of torsemide:

Alternative drugs to, pros and cons of Demadex:

Common Demadex side effects:

Browse all side effects of Demadex:

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Blood creatine increased treatments and more:

COVID vaccines that are related to Blood creatine increased:

Common drugs associated with Blood creatine increased:

All the drugs that are associated with Blood creatine increased:

Common conditions associated with Blood creatine increased:

All the conditions that are associated with Blood creatine increased:

How the study uses the data?

The study uses data from the FDA. It is based on torsemide (the active ingredients of Demadex) and Demadex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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