Demerol and Cardiac failure - a phase IV clinical study of FDA data

Summary:

Cardiac failure is found among people who take Demerol, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Demerol and have Cardiac failure. It is created by eHealthMe based on reports of 11,286 people who have side effects when taking Demerol from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jan, 27, 2023

11,286 people reported to have side effects when taking Demerol.
Among them, 51 people (0.45%) have Cardiac failure.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 11,585 Demerol users for its effectiveness, alternative drugs and more.

What is Cardiac failure?

Cardiac failure is found to be associated with 2,610 drugs and 2,148 conditions by eHealthMe.

Number of Demerol and Cardiac failure reports submitted per year:

Time on Demerol when people have Cardiac failure *:

Gender of people who have Cardiac failure when taking Demerol *:

female: 62 %
male: 38 %

Age of people who have Cardiac failure when taking Demerol *:

Common drugs people take besides Demerol *:

Common side effects people have besides Cardiac failure *:

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 17 people, 33.33%
Fatigue (feeling of tiredness): 15 people, 29.41%
Hypotension (abnormally low blood pressure): 14 people, 27.45%
Developmental Delay: 13 people, 25.49%
Coarctation Of The Aorta (narrowing of the part of aorta): 13 people, 25.49%
Chest Pain: 13 people, 25.49%
Laryngeal Nerve Damage: 13 people, 25.49%
Weakness: 13 people, 25.49%
Organ Failure: 13 people, 25.49%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 11 people, 21.57%

Common conditions people have *:

Depression: 8 people, 15.69%
Stress And Anxiety: 2 people, 3.92%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 3.92%
Type 2 Diabetes: 1 person, 1.96%
Hypersensitivity: 1 person, 1.96%
Anaemia (lack of blood): 1 person, 1.96%
Bleeding Disorders: 1 person, 1.96%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 1.96%
Chest Pain: 1 person, 1.96%
Constipation: 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Demerol and have Cardiac failure?

Check whether Cardiac failure is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Cardiac failure and when was it recovered:

Cardiac failure in Demerol

Expand to all the drugs that have ingredients of meperidine hydrochloride:

Cardiac failure and drugs with ingredients of meperidine hydrochloride

Alternative drugs to, pros and cons of Demerol:

Demerol (11,585 reports)

Common Demerol side effects:

Pain: 1,582 reports
Drug ineffective: 1,221 reports
Nausea and vomiting: 1,049 reports
Rashes (redness): 908 reports
Stress and anxiety: 835 reports

Browse all side effects of Demerol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Cardiac failure treatments and more:

Cardiac failure (126,682 reports)

COVID vaccines that are related to Cardiac failure:

Common drugs associated with Cardiac failure:

All the drugs that are associated with Cardiac failure:

Cardiac failure (2,610 drugs)

Common conditions associated with Cardiac failure:

High blood pressure: 5,543 reports
Primary pulmonary hypertension: 4,007 reports
Atrial fibrillation/flutter: 3,555 reports
Rheumatoid arthritis: 3,335 reports
Diabetes: 3,205 reports
Multiple myeloma: 2,367 reports
Type 2 diabetes: 2,118 reports

All the conditions that are associated with Cardiac failure:

Cardiac failure (2,148 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on meperidine hydrochloride (the active ingredients of Demerol) and Demerol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.