Demerol and Oesophageal stenosis - a phase IV clinical study of FDA data


Oesophageal stenosis is reported only by a few people who take Demerol.

The phase IV clinical study analyzes which people take Demerol and have Oesophageal stenosis. It is created by eHealthMe based on reports of 11,286 people who have side effects while taking Demerol from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 11, 2022

11,286 people reported to have side effects when taking Demerol.
Among them, 5 people (0.04%) have Oesophageal stenosis.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 11,585 Demerol users for its effectiveness, alternative drugs and more.

What is Oesophageal stenosis?

Oesophageal stenosis (narrowing of oesophagus) is found to be associated with 924 drugs and 497 conditions by eHealthMe.

Number of Demerol and Oesophageal stenosis reports submitted per year:

Could Demerol cause Oesophageal stenosis?

Gender of people who have Oesophageal stenosis when taking Demerol *:

  • female: 80 %
  • male: 20 %

Age of people who have Oesophageal stenosis when taking Demerol *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 60 %
  • 50-59: 40 %
  • 60+: 0.0 %

Common drugs people take besides Demerol *:

  1. Vioxx: 4 people, 80.00%
  2. Dilaudid: 4 people, 80.00%
  3. Miacalcin: 3 people, 60.00%
  4. Climara: 3 people, 60.00%
  5. Flexeril: 2 people, 40.00%
  6. Zomig: 1 person, 20.00%
  7. Lasix: 1 person, 20.00%
  8. Lanoxicaps: 1 person, 20.00%
  9. Kenalog: 1 person, 20.00%
  10. Keflex: 1 person, 20.00%

Common side effects people have besides Oesophageal stenosis *:

  1. Urinary Tract Infection: 4 people, 80.00%
  2. Fall: 3 people, 60.00%
  3. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 3 people, 60.00%
  4. Limb Injury: 3 people, 60.00%
  5. Kidney Stones: 3 people, 60.00%
  6. Hip Fracture: 3 people, 60.00%
  7. Heart Attack: 3 people, 60.00%
  8. Femoral Neck Fracture (neck of femur bone fracture): 3 people, 60.00%
  9. Drug Withdrawal Convulsions: 3 people, 60.00%
  10. Oesophageal Disorder (disease of oesophagus): 3 people, 60.00%

Common conditions people have *:

  1. Osteoporosis (bones weak and more likely to break): 3 people, 60.00%
  2. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 20.00%
  3. Kidney Stones: 1 person, 20.00%
  4. Headache (pain in head): 1 person, 20.00%
  5. Back Pain: 1 person, 20.00%

* Approximation only. Some reports may have incomplete information.

Do you take Demerol and have Oesophageal stenosis?

Check whether Oesophageal stenosis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Oesophageal stenosis and when was it recovered:

Expand to all the drugs that have ingredients of meperidine hydrochloride:

Alternative drugs to, pros and cons of Demerol:

Common Demerol side effects:

Browse all side effects of Demerol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Oesophageal stenosis treatments and more:

COVID vaccines that are related to Oesophageal stenosis:

Common drugs associated with Oesophageal stenosis:

All the drugs that are associated with Oesophageal stenosis:

Common conditions associated with Oesophageal stenosis:

All the conditions that are associated with Oesophageal stenosis:

How the study uses the data?

The study uses data from the FDA. It is based on meperidine hydrochloride (the active ingredients of Demerol) and Demerol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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