Depakote er and Speech impairment (adult) - a phase IV clinical study of FDA data

Summary:

We study 4,988 people who have side effects when taking Depakote er. Speech impairment (adult) is found, especially among people who are female, 40-49 old, have been taking the drug for < 1 month, also take Seroquel and have Depression.

The phase IV clinical study analyzes which people take Depakote er and have Speech impairment (adult). It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

4,988 people reported to have side effects when taking Depakote er.
Among them, 60 people (1.2%) have Speech impairment (adult).

What is Depakote er?

Depakote er has active ingredients of divalproex sodium. It is used in bipolar disorder. Currently, eHealthMe is studying from 5,921 Depakote er users.

What is Speech impairment (adult)?

Speech impairment (adult) (inability to speak (adult)) is found to be associated with 3,682 drugs and 3,465 conditions by eHealthMe. Currently, we are studying 79,047 people who have Speech impairment (adult).

Number of Depakote er and Speech impairment (adult) reports submitted per year:

Could Depakote er cause Speech impairment (adult)?

Time on Depakote er when people have Speech impairment (adult) *:

Gender of people who have Speech impairment (adult) when taking Depakote er *:

female: 56.9 %
male: 43.1 %

Age of people who have Speech impairment (adult) when taking Depakote er *:

Common drugs people take besides Depakote er *:

Common side effects people have besides Speech impairment (adult) *:

Fatigue (feeling of tiredness): 10 people, 16.67%
Drowsiness: 10 people, 16.67%
Weakness: 9 people, 15.00%
Memory Loss: 8 people, 13.33%
Confusional State: 8 people, 13.33%
Fall: 8 people, 13.33%
Tremor (trembling or shaking movements in one or more parts of your body): 7 people, 11.67%
Balance Disorder: 7 people, 11.67%
Stress And Anxiety: 7 people, 11.67%
Dizziness: 6 people, 10.00%

Common conditions people have *:

Depression: 15 people, 25.00%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 10.00%
Stress And Anxiety: 4 people, 6.67%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 6.67%
Mania (a state of abnormally elevated or irritable mood): 4 people, 6.67%
Constipation: 4 people, 6.67%
High Blood Pressure: 3 people, 5.00%
Affective Disorder (mental disorder): 3 people, 5.00%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 3 people, 5.00%
Migraine (headache): 2 people, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Depakote er and have Speech impairment (adult)?

Check whether Speech impairment (adult) is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Depakote er side effects by duration, gender and age:

Depakote er side effects (5,921 reports)

Speech impairment (adult) treatments and more:

Speech impairment (adult) (79,047 reports)

Common drugs associated with Speech impairment (adult):

All the drugs that are associated with Speech impairment (adult):

Speech impairment (adult) (3,682 drugs)

Common conditions associated with Speech impairment (adult):

Multiple sclerosis: 6,963 reports
High blood pressure: 3,630 reports
Depression: 3,087 reports
Pain: 2,677 reports

All the conditions that are associated with Speech impairment (adult):

Speech impairment (adult) (3,465 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote er) and Depakote er (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.