Depakote and Mydriasis - from FDA reports

Mydriasis is found among people who take Depakote, especially for people who are female, 30-39 old , have been taking the drug for < 1 month, also take medication Seroquel, and have Pain. This study is created by eHealthMe based on reports of 41,621 people who have side effects when taking Depakote from FDA, and is updated regularly.

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On Nov, 05, 2018

41,621 people reported to have side effects when taking Depakote.
Among them, 72 people (0.17%) have Mydriasis

Number of reports submitted per year:

Could Depakote cause Mydriasis?

Time on Depakote when people have Mydriasis *:

  • < 1 month: 70 %
  • 1 - 6 months: 10 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Mydriasis when taking Depakote *:

  • female: 65.71 %
  • male: 34.29 %

Age of people who have Mydriasis when taking Depakote *:

  • 0-1: 0.0 %
  • 2-9: 6.06 %
  • 10-19: 21.21 %
  • 20-29: 10.61 %
  • 30-39: 30.3 %
  • 40-49: 16.67 %
  • 50-59: 15.15 %
  • 60+: 0.0 %

Top conditions involved for these people *:

  1. Pain: 15 people, 20.83%
  2. Psychotic Disorder: 2 people, 2.78%
  3. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 2.78%
  4. Depression: 2 people, 2.78%
  5. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 2.78%

Click here to view more results or personalize the results to your gender and age

Top co-used drugs for these people *:

  1. Seroquel: 25 people, 34.72%
  2. Xanax: 24 people, 33.33%
  3. Klonopin: 21 people, 29.17%
  4. Risperdal: 21 people, 29.17%
  5. Clonidine: 20 people, 27.78%

Click here to view more results or personalize the results to your gender and age

Top other side effects for these people *:

  1. Speech Impairment (Adult) (inability to speak (adult)): 24 people, 33.33%
  2. High Blood Pressure: 21 people, 29.17%
  3. Agitation (state of anxiety or nervous excitement): 21 people, 29.17%
  4. Stress And Anxiety: 21 people, 29.17%
  5. Sedation: 19 people, 26.39%

Click here to view more results or personalize the results to your gender and age

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

Do you have Mydriasis while taking Depakote?

You are not alone:

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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