Depakote and Pain - a phase IV clinical study of FDA data

Summary:

We study 49,884 people who have side effects when taking Depakote. Pain is found, especially among people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take Seroquel and have Depression.

The phase IV clinical study analyzes which people take Depakote and have Pain. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

What are phase IV trials?

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 15, 2023

49,884 people reported to have side effects when taking Depakote.
Among them, 2,310 people (4.63%) have Pain.

What is Depakote?

Depakote has active ingredients of divalproex sodium. It is used in bipolar disorder. Currently, eHealthMe is studying from 54,472 Depakote users.

What is Pain?

Pain is found to be associated with 5,320 drugs and 5,716 conditions by eHealthMe. Currently, we are studying 1,088,462 people who have Pain.

Number of Depakote and Pain reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Depakote and have Pain?

Check whether Pain is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Pain and when was it recovered:

Pain in Depakote

Expand to all the drugs that have ingredients of divalproex sodium:

Pain and drugs with ingredients of divalproex sodium (2,499 reports)

Alternative drugs to, pros and cons of Depakote:

Depakote (54,472 reports)

Browse all side effects of Depakote:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Pain treatments and more:

Pain (1,088,462 reports)

Common drugs associated with Pain:

All the drugs that are associated with Pain:

Pain (5,320 drugs)

Common conditions associated with Pain:

Rheumatoid arthritis: 88,017 reports
Multiple sclerosis: 29,170 reports
High blood pressure: 19,549 reports

All the conditions that are associated with Pain:

Pain (5,716 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote) and Depakote (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.