Depakote and Psoriasis - a phase IV clinical study of FDA data
Summary:
Psoriasis is found among people who take Depakote, especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months.
The phase IV clinical study analyzes which people take Depakote and have Psoriasis. It is created by eHealthMe based on reports of 49,884 people who have side effects when taking Depakote from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
49,884 people reported to have side effects when taking Depakote.
Among them, 103 people (0.21%) have Psoriasis.
What is Depakote?
Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 52,737 Depakote users for its effectiveness, alternative drugs and more.
What is Psoriasis?
Psoriasis (immune-mediated disease that affects the skin) is found to be associated with 2,266 drugs and 1,580 conditions by eHealthMe.
Number of Depakote and Psoriasis reports submitted per year:

Time on Depakote when people have Psoriasis *:
Gender of people who have Psoriasis when taking Depakote*:
Age of people who have Psoriasis when taking Depakote *:
Common drugs people take besides Depakote *:
Common side effects people have besides Psoriasis *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Depakote and have Psoriasis?
Check whether Psoriasis is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Mohagheghi MA, Omranipur R, Ensani F, Ghannadan A, Shahriaran S, Samiee F, Sedighi Z, "A Case of Advanced Unicentric Retroperitoneal Castleman's Disease, Associated With Psoriasis", Acta Medica Iranica, 2017 May .
- Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
- Malisiewicz B, Murer C, Schmid JP, French LE, Schmid-Grendelmeier P, Navarini AA, "Eosinophilia during psoriasis treatment with TNF antagonists", Dermatology, 2013 Jan .
Related studies
How severe was Psoriasis and when was it recovered:
Expand to all the drugs that have ingredients of divalproex sodium:
Alternative drugs to, pros and cons of Depakote:
- Depakote (52,737 reports)
Common Depakote side effects:
- Abasia (inability to walk): 191 reports
- Abdominal discomfort: 311 reports
- Abdominal distension: 273 reports
- Abdominal pain: 635 reports
- Abdominal pain upper: 557 reports
- Abnormal behavior: 854 reports
- Abnormal dreams: 218 reports
- Abortion spontaneous (naturally occurring miscarriage): 126 reports
- Accidental overdose (therapeutic agent): 159 reports
- Activities of daily living impaired: 355 reports
- Acute kidney failure: 478 reports
- Acute upper airway obstruction (blockage occurs in the upper airway): 112 reports
- Adverse drug reaction: 262 reports
- Adverse event: 248 reports
- Aggression: 1,071 reports
- Agitation (state of anxiety or nervous excitement): 1,387 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1,140 reports
- Akathisia (a movement disorder characterized by a feeling of inner restlessness): 182 reports
- Alanine aminotransferase increased: 322 reports
- Alcoholism (problems with alcohol): 151 reports
- Ammonia increased: 396 reports
- Anaemia (lack of blood): 604 reports
- Anger: 516 reports
- Anhedonia (inability to experience pleasure from activities usually found enjoyable): 758 reports
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight): 206 reports
- Anticonvulsant drug level decreased: 102 reports
- Apathy: 138 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 689 reports
- Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires): 351 reports
- Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system): 107 reports
- Arrhythmias (irregular heartbeat): 522 reports
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 185 reports
- Aspartate aminotransferase increased: 307 reports
- Asthma: 314 reports
- Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 234 reports
- Atrial septal defect (an abnormal opening between the left and right atria of the heart): 106 reports
- Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 106 reports
- Back pain: 803 reports
- Balance disorder: 567 reports
- Bipolar disorder (mood disorder): 691 reports
- Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode): 186 reports
- Blindness: 108 reports
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 153 reports
- Blood creatine phosphokinase increased: 245 reports
- Blood creatinine increased: 174 reports
- Blood glucose decreased: 147 reports
- Blood glucose increased: 530 reports
- Blood potassium decreased: 107 reports
- Blood prolactin increased: 114 reports
- Blood sodium decreased: 136 reports
- Blood urea increased: 163 reports
- Body temperature increased: 109 reports
- Bone pain: 119 reports
- Bradycardia (abnormally slow heart action): 147 reports
- Breathing difficulty: 1,171 reports
- Breathing - slowed or stopped: 109 reports
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 318 reports
- Burning sensation: 188 reports
- Cardiac arrest: 293 reports
- Cardiac disorder: 294 reports
- Cardiac failure congestive: 251 reports
- Cardiac murmur (an heart sound in valve abnormality): 110 reports
- Cardiomyopathy (weakening of the heart muscle): 111 reports
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs): 132 reports
- Cataract (clouding of the lens inside the eye): 169 reports
- Cellulitis (infection under the skin): 311 reports
- Cerebral atrophy (decrement in size of brain): 113 reports
- Chest pain: 1,019 reports
- Chills (felling of cold): 317 reports
- Chronic kidney disease: 250 reports
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 253 reports
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving): 450 reports
- Completed suicide (act of taking one's own life): 187 reports
- Condition: 1,004 reports
- Confusion: 662 reports
- Confusional state: 1,247 reports
- Congenital anomaly (birth defect): 316 reports
- Consciousness - decreased: 597 reports
- Constipation: 738 reports
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1,962 reports
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly): 334 reports
- Coronary heart disease (narrowing or blockage of the coronary arteries): 118 reports
- Cough: 507 reports
- Crying: 319 reports
- Cuts and puncture wounds: 106 reports
- Death: 783 reports
- Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 245 reports
- Deformity (disfigurement): 655 reports
- Dehydration (dryness resulting from the removal of water): 628 reports
- Delirium (wild excitement): 243 reports
- Delusion (a false belief or opinion): 330 reports
- Dementia (madness): 218 reports
- Depressed level of consciousness: 297 reports
- Depressed mood: 286 reports
- Depression: 2,086 reports
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 189 reports
- Developmental delay: 145 reports
- Diabetes: 1,604 reports
- Diabetes mellitus inadequate control: 395 reports
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 639 reports
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus): 288 reports
- Diarrhea: 1,555 reports
- Difficulty in walking: 130 reports
- Diplopia (double vision): 178 reports
- Disability: 174 reports
- Disease recurrence: 107 reports
- Disturbance in attention: 488 reports
- Dizziness: 1,803 reports
- Drooling (drop saliva uncontrollably from the mouth): 219 reports
- Drowsiness: 2,191 reports
- Drug abuse and dependence: 227 reports
- Drug administration error: 108 reports
- Drug dependence: 316 reports
- Drug effect decreased: 269 reports
- Drug exposure during pregnancy: 422 reports
- Drug hypersensitivity: 683 reports
- Drug ineffective: 2,665 reports
- Drug intolerance (drug sensitivity): 142 reports
- Drug level decreased: 275 reports
- Drug level increased: 307 reports
- Drug maladministration: 115 reports
- Drug toxicity: 267 reports
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 383 reports
- Dry mouth: 332 reports
- Dry skin: 118 reports
- Dyskinesia (abnormality or impairment of voluntary movement): 466 reports
- Dysstasia (difficulty in standing): 138 reports
- Ear pain: 109 reports
- Eating disorder: 163 reports
- Electrocardiogram qt prolonged: 219 reports
- Emotional disorder: 289 reports
- Emotional distress: 1,113 reports
- Encephalopathy (functioning of the brain is affected by some agent or condition): 303 reports
- Enlarged heart: 101 reports
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 270 reports
- Erection problems: 292 reports
- Erythema multiforme (a type of hypersensitivity reaction): 289 reports
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck): 318 reports
- Eye disorder: 113 reports
- Eye pain: 116 reports
- Face oedema (swelling of face): 117 reports
- Fainting (loss of consciousness and postural tone): 394 reports
- Fall: 1,885 reports
- Fatigue (feeling of tiredness): 2,716 reports
- Fear: 173 reports
- Feeling hot: 155 reports
- Fever: 1,284 reports
- Fibromyalgia (a long-term condition which causes pain all over the body): 149 reports
- Flatulence (flatus expelled through the anus): 138 reports
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 730 reports
- Foot fracture: 123 reports
- Gait disturbance: 873 reports
- Gallbladder disorder: 127 reports
- Gallstones (stone formation by bile component): 171 reports
- Gastric disorder (disease of stomach): 140 reports
- Gastric ulcer (stomach ulcer): 144 reports
- Gastritis (inflammation of stomach): 150 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 432 reports
- Gastrointestinal disorder (functional problems of gastrointestinal tract): 215 reports
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract): 163 reports
- General physical health deterioration (weak health status): 248 reports
- Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 107 reports
- Grand mal convulsion (a type of generalized seizure that affects the entire brain): 398 reports
- Gynecomastia (enlargement of the gland tissue of the male breast): 440 reports
- Haematemesis (vomiting of blood): 112 reports
- Haematochezia (passage of stools containing blood): 123 reports
- Haematocrit decreased: 128 reports
- Haemoglobin decreased: 280 reports
- Haemorrhage (bleeding): 183 reports
- Haemorrhoids (a swollen vein or group of veins in the region of the anus): 114 reports
- Hair loss: 1,211 reports
- Hallucination, auditory (perceiving sounds without auditory stimulus): 343 reports
- Hallucinations (sensations that appear real but are created by your mind): 639 reports
- Hallucination, visual (seeing things that aren't there): 175 reports
- Headache (pain in head): 1,841 reports
- Head injury: 756 reports
- Hearing loss: 120 reports
- Heart attack: 471 reports
- Heart palpitations (feelings or sensations that your heart is pounding or racing): 398 reports
- Heart rate increased: 322 reports
- Hepatic enzyme increased: 243 reports
- Hepatic failure (liver failure): 184 reports
- Hepatic steatosis (fatty liver disease): 185 reports
- Hepatitis (inflammation of the liver): 127 reports
- High blood cholesterol: 1,035 reports
- High blood pressure: 1,464 reports
- Hoarseness or changing voice: 115 reports
- Homicidal ideation (thoughts about human killing another human): 131 reports
- Hospitalisation: 391 reports
- Hostility: 135 reports
- Hot flush (sudden feelings of heat): 113 reports
- Hyperammonaemia: 246 reports
- Hyperglycemia (high blood sugar): 428 reports
- Hyperhidrosis (abnormally increased sweating): 420 reports
- Hyperkalemia (damage to or disease of the kidney): 150 reports
- Hyperlipidaemia (presence of excess lipids in the blood): 350 reports
- Hypernatraemia (an abnormally high plasma concentration of sodium ions): 109 reports
- Hyperprolactinaemia (abnormally high levels of prolactin in the blood): 109 reports
- Hypersensitivity: 411 reports
- Hypoaesthesia (reduced sense of touch or sensation): 536 reports
- Hypoglycemia (low blood sugar): 291 reports
- Hypokalemia (low potassium): 135 reports
- Hypomania (a mild form of mania, marked by elation and hyperactivity): 147 reports
- Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 332 reports
- Hypotension (abnormally low blood pressure): 873 reports
- Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions): 115 reports
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 228 reports
- Ill-defined disorder: 216 reports
- Impaired work ability: 307 reports
- Incontinence (lack of moderation or self-control): 116 reports
- Indigestion: 315 reports
- Infection: 268 reports
- Influenza like illness: 238 reports
- Injection site pain: 267 reports
- Injury: 884 reports
- Insomnia (sleeplessness): 1,910 reports
- Intentional overdose: 215 reports
- Intentional self-injury: 183 reports
- International normalised ratio increased: 115 reports
- Intervertebral disc protrusion (spinal disc protrusion): 155 reports
- Intestinal obstruction: 113 reports
- Irritability: 638 reports
- Irritable bowel syndrome: 112 reports
- Itching: 508 reports
- Joint injury: 107 reports
- Joint pain: 749 reports
- Joint stiffness: 109 reports
- Joint swelling: 218 reports
- Kidney stones: 149 reports
- Leukocytosis (increased white blood cells): 105 reports
- Leukopenia (less number of white blood cells in blood): 382 reports
- Limb injury: 116 reports
- Liver disorder (liver diseases): 152 reports
- Loss of consciousness: 813 reports
- Loss of employment: 381 reports
- Low tissue oxygen: 134 reports
- Lung disorder (lung disease): 142 reports
- Lymph follicular hypertrophy (an increase in the size of the lymph node follicles): 203 reports
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 138 reports
- Malaise (a feeling of general discomfort or uneasiness): 1,151 reports
- Mania (a state of abnormally elevated or irritable mood): 863 reports
- Maternal exposure during pregnancy (use of substance during pregnancy): 174 reports
- Memory loss: 1,387 reports
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 526 reports
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 307 reports
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 320 reports
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 142 reports
- Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 126 reports
- Migraine (headache): 633 reports
- Mobility decreased (ability to move is reduced): 190 reports
- Mood swings (an extreme or rapid change in mood): 568 reports
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 170 reports
- Movement - uncontrolled or slow: 165 reports
- Movement - uncoordinated: 181 reports
- Multiple congenital abnormalities (more than one birth defects): 124 reports
- Multiple injuries: 254 reports
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 194 reports
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 175 reports
- Muscle aches (muscle pain): 419 reports
- Muscle rigidity (muscle stiffness): 143 reports
- Muscle spasms (muscle contraction): 489 reports
- Muscle twitching: 172 reports
- Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 166 reports
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 215 reports
- Myelomeningocele (children) (a defect of the backbone and spinal cord, which don't close properly before birth): 439 reports
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 102 reports
- Nasopharyngitis (inflammation of the nasopharynx): 289 reports
- Nausea (feeling of having an urge to vomit): 2,214 reports
- Nausea and vomiting: 1,501 reports
- Neck pain: 270 reports
- Nervousness: 426 reports
- Nervous system disorder (a general class of medical conditions affecting the nervous system): 191 reports
- Neural tube defect (birth defects of the brain, spine, or spinal cord): 335 reports
- Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 321 reports
- Neuropathy peripheral (surface nerve damage): 468 reports
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell): 207 reports
- Nightmares (unpleasant dreams): 295 reports
- Nosebleed (bleeding from nose): 155 reports
- Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 195 reports
- Oedema (fluid collection in tissue): 343 reports
- Oedema peripheral (superficial swelling): 679 reports
- Oropharyngeal pain: 174 reports
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 151 reports
- Osteopenia (a condition where bone mineral density is lower than normal): 103 reports
- Osteoporosis (bones weak and more likely to break): 237 reports
- Otitis (ear infection): 127 reports
- Overdose: 1,044 reports
- Oxygen saturation decreased: 190 reports
- Pain: 2,310 reports
- Pain in extremity: 734 reports
- Paleness (unusual lightness of skin colour): 131 reports
- Pancreatitis (inflammation of pancreas): 911 reports
- Pancreatitis acute (sudden inflammation of pancreas): 213 reports
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 196 reports
- Panic disorder: 357 reports
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 510 reports
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 410 reports
- Parkinson's disease: 295 reports
- Partial seizures (seizures which affect only a part of the brain at onset): 101 reports
- Peripheral swelling: 260 reports
- Petit mal epilepsy (absence seizure): 200 reports
- Photophobia (extreme sensitivity to light): 115 reports
- Physical disability: 594 reports
- Pleural effusion (water on the lungs): 224 reports
- Pneumonia: 1,122 reports
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 198 reports
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 187 reports
- Poor quality sleep: 151 reports
- Post-traumatic stress disorder: 113 reports
- Prescribed overdose: 217 reports
- Psoriasis (immune-mediated disease that affects the skin): 103 reports
- Psychomotor hyperactivity (feelings of extreme restlessness): 252 reports
- Psychotic disorder: 769 reports
- Pulmonary embolism (blockage of the main artery of the lung): 301 reports
- Pulmonary oedema (fluid accumulation in the lungs): 167 reports
- Quality of life decreased: 116 reports
- Rashes (redness): 1,338 reports
- Rectal haemorrhage (bleeding from anus): 159 reports
- Red blood cell count decreased: 126 reports
- Renal disorder (kidney disease): 151 reports
- Renal failure acute (rapid kidney dysfunction): 307 reports
- Renal impairment (severely reduced kidney function): 120 reports
- Respiratory acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 194 reports
- Respiratory disorder (respiratory disease): 103 reports
- Respiratory distress (difficulty in breathing): 151 reports
- Restless leg syndrome (a powerful urge to move your legs): 172 reports
- Retching (strong involuntary effort to vomit): 126 reports
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 301 reports
- Rib fracture: 108 reports
- Road traffic accident: 361 reports
- Salivary hypersecretion (excess saliva secretion): 130 reports
- Scar: 111 reports
- Schizoaffective disorder (a mental disorder characterized by disordered thought): 199 reports
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 215 reports
- Sedation: 856 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1,943 reports
- Sepsis (a severe blood infection that can lead to organ failure and death): 352 reports
- Sinusitis (inflammation of sinus): 312 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 149 reports
- Skin discoloration: 188 reports
- Skin exfoliation (removal of the oldest dead skin cells): 114 reports
- Sleep apnea syndrome: 320 reports
- Sleep disorder: 330 reports
- Social problem: 310 reports
- Speech disorder: 594 reports
- Speech impairment (adult) (inability to speak (adult)): 678 reports
- Staphylococcal infection (an infection with staphylococcus bacteria): 117 reports
- Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 168 reports
- Stomatitis (inflammation of mucous membrane of mouth): 115 reports
- Stress and anxiety: 2,400 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 489 reports
- Suicidal ideation: 1,210 reports
- Suicide attempt: 844 reports
- Surgery: 113 reports
- Swallowing difficulty: 534 reports
- Swelling: 238 reports
- Swelling face: 151 reports
- Tardive dyskinesia (a disorder that involves involuntary movements): 427 reports
- Taste - impaired: 119 reports
- The flu (the flu is caused by an influenza virus): 212 reports
- Therapeutic response decreased (less preventive response): 120 reports
- Therapeutic response unexpected: 147 reports
- Thirst: 146 reports
- Thrombocytopenia (decrease of platelets in blood): 1,154 reports
- Thrombosis (formation of a blood clot inside a blood vessel): 166 reports
- Tinnitus (a ringing in the ears): 241 reports
- Tooth abscess (pus formation in tooth): 102 reports
- Tooth disorder (tooth disease): 124 reports
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 188 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 2,179 reports
- Type 1 diabetes: 296 reports
- Type 2 diabetes: 1,290 reports
- Unresponsive to stimuli: 130 reports
- Upper respiratory tract infection: 200 reports
- Urinary incontinence (inability to control the flow of urine and involuntary urination): 411 reports
- Urinary retention (the inability to completely or partially empty the bladder): 157 reports
- Urinary tract infection: 776 reports
- Urination - excessive volume: 124 reports
- Urination - painful: 212 reports
- Urticaria (rash of round, red welts on the skin that itch intensely): 266 reports
- Viral infection: 119 reports
- Vision blurred: 660 reports
- Visual acuity reduced (reduced clearness of vision): 131 reports
- Visual impairment: 283 reports
- Weakness: 1,774 reports
- Weight decreased: 1,257 reports
- Weight increased: 2,766 reports
- Weight loss: 635 reports
- White blood cell count decreased: 491 reports
- White blood cell count increased: 256 reports
- Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 175 reports
Browse all side effects of Depakote:
a b c d e f g h i j k l m n o p q r s t u v w x y zPsoriasis treatments and more:
- Psoriasis (412,198 reports)
COVID vaccines that are related to Psoriasis:
- Psoriasis in Moderna COVID Vaccine
- Psoriasis in Pfizer BioNTech Covid Vaccine
- Psoriasis in Johnson and Johnson Covid Vaccine
Common drugs associated with Psoriasis:
- Abilify: 204 reports
- Accutane: 109 reports
- Acetaminophen: 326 reports
- Acetylsalicylic acid: 439 reports
- Acitretin: 1,133 reports
- Actemra: 1,093 reports
- Adderall: 185 reports
- Advair hfa: 339 reports
- Advil: 305 reports
- Albuterol: 593 reports
- Albuterol sulfate: 146 reports
- Alendronate sodium: 204 reports
- Aleve: 266 reports
- Allegra: 309 reports
- Allopurinol: 692 reports
- Alprazolam: 483 reports
- Ambien: 450 reports
- Amevive: 594 reports
- Amlodipine: 1,815 reports
- Amlodipine besylate: 265 reports
- Amoxicillin: 307 reports
- Apremilast: 176 reports
- Arava: 692 reports
- Aredia: 102 reports
- Arthrotec: 143 reports
- Asa: 258 reports
- Asacol: 132 reports
- Aspirin: 2,803 reports
- Atarax: 229 reports
- Atenolol: 919 reports
- Ativan: 233 reports
- Atorvastatin calcium: 174 reports
- Augmentin: 125 reports
- Avapro: 165 reports
- Avonex: 172 reports
- Azathioprine: 341 reports
- Baby aspirin: 212 reports
- Baclofen: 320 reports
- Bactrim: 115 reports
- Benadryl: 404 reports
- Benicar: 157 reports
- Betaderm: 195 reports
- Betamethasone valerate: 178 reports
- Biotin: 225 reports
- Bisoprolol fumarate: 135 reports
- Budesonide: 203 reports
- Bupropion hydrochloride: 139 reports
- Bystolic: 138 reports
- Calcipotriene and betamethasone dipropionate: 166 reports
- Calcium: 966 reports
- Carbamazepine: 104 reports
- Carvedilol: 534 reports
- Celebrex: 1,238 reports
- Celecoxib: 388 reports
- Celexa: 314 reports
- Centrum: 161 reports
- Cephalexin: 149 reports
- Cetirizine hydrochloride: 167 reports
- Chantix: 137 reports
- Cimzia: 1,983 reports
- Citalopram hydrobromide: 156 reports
- Claritin: 381 reports
- Clobetasol propionate: 374 reports
- Clobex: 200 reports
- Clonazepam: 731 reports
- Clonidine: 226 reports
- Clopidogrel: 276 reports
- Codeine: 504 reports
- Codeine sulfate: 107 reports
- Colace: 110 reports
- Colecalciferol: 178 reports
- Coreg: 117 reports
- Cosentyx: 21,919 reports
- Coumadin: 239 reports
- Cozaar: 151 reports
- Crestor: 629 reports
- Cyclosporine: 1,057 reports
- Cymbalta: 985 reports
- Demerol: 427 reports
- Depakote: 103 reports
- Desonide: 193 reports
- Desoximetasone: 237 reports
- Dexamethasone: 120 reports
- Dexilant: 251 reports
- Diazepam: 297 reports
- Diclofenac: 478 reports
- Diclofenac sodium: 200 reports
- Digoxin: 154 reports
- Dilaudid: 155 reports
- Diovan: 337 reports
- Diphenhydramine hydrochloride: 112 reports
- Dovonex: 713 reports
- Doxycycline: 327 reports
- Dupixent: 657 reports
- Effexor: 395 reports
- Effexor xr: 101 reports
- Elavil: 135 reports
- Eliquis: 227 reports
- Enbrel: 26,257 reports
- Enstilar: 223 reports
- Entresto: 129 reports
- Ergocalciferol: 385 reports
- Escitalopram: 423 reports
- Esomeprazole magnesium: 165 reports
- Ezetimibe: 158 reports
- Famotidine: 202 reports
- Fenofibrate: 356 reports
- Finasteride: 107 reports
- Fish oil: 913 reports
- Flexeril: 284 reports
- Flomax: 188 reports
- Flonase: 279 reports
- Flovent: 128 reports
- Fluconazole: 158 reports
- Fluocinonide: 264 reports
- Fluoxetine: 487 reports
- Folic acid: 1,053 reports
- Fosamax: 447 reports
- Furosemide: 962 reports
- Gabapentin: 1,625 reports
- Gemfibrozil: 102 reports
- Gilenya: 189 reports
- Gliclazide: 172 reports
- Glimepiride: 219 reports
- Glipizide: 350 reports
- Glucophage: 164 reports
- Glyburide: 162 reports
- Hctz: 321 reports
- Humalog: 268 reports
- Humira: 23,088 reports
- Hydramine: 365 reports
- Hydrochlorothiazide: 1,082 reports
- Hydrocodone bitartrate and acetaminophen: 129 reports
- Hydroxychloroquine sulfate: 502 reports
- Hydroxyzine: 557 reports
- Ibu: 1,579 reports
- Ibuprofen: 1,559 reports
- Imuran: 241 reports
- Indomethacin: 177 reports
- Inflectra: 451 reports
- Insulin: 370 reports
- Irbesartan: 247 reports
- Isoniazid: 125 reports
- Isosorbide mononitrate: 109 reports
- Januvia: 361 reports
- Jardiance: 143 reports
- Ketoconazole: 240 reports
- Keytruda: 123 reports
- Kineret: 210 reports
- Klonopin: 287 reports
- Klor-con: 110 reports
- Lamictal: 185 reports
- Lamisil: 118 reports
- Lamotrigine: 203 reports
- Lansoprazole: 315 reports
- Lantus: 514 reports
- Lasix: 558 reports
- Leflunomide: 1,255 reports
- Levaquin: 105 reports
- Levothyroxine sodium: 399 reports
- Lexapro: 407 reports
- Lipitor: 972 reports
- Lisinopril: 2,358 reports
- Lopurin: 698 reports
- Loratadine: 243 reports
- Loraz: 449 reports
- Lorazepam: 449 reports
- Lortab: 124 reports
- Losartan: 1,339 reports
- Losartan potassium: 384 reports
- Lovastatin: 202 reports
- Lyrica: 972 reports
- Magnesium: 450 reports
- Medrol: 130 reports
- Melatonin: 192 reports
- Meloxicam: 896 reports
- Mercaptopurine: 119 reports
- Metformin: 2,821 reports
- Metformin hydrochloride: 194 reports
- Methotrexate: 10,887 reports
- Methotrexate sodium: 1,001 reports
- Metoprolol succinate: 240 reports
- Metoprolol tartrate: 351 reports
- Metronidazole: 167 reports
- Micardis: 116 reports
- Mirena: 121 reports
- Mirtazapine: 196 reports
- Mobic: 180 reports
- Mometasone furoate: 105 reports
- Morphine: 960 reports
- Morphine sulfate: 437 reports
- Motrin: 127 reports
- Moxifloxacin: 242 reports
- Multivitamin: 604 reports
- Nabumetone: 113 reports
- Naprosyn: 116 reports
- Naproxen: 677 reports
- Nasonex: 167 reports
- Neoral: 469 reports
- Neurontin: 344 reports
- Nexium: 683 reports
- Nifedipine: 139 reports
- Nitroglycerin: 151 reports
- Norco: 203 reports
- Norvasc: 428 reports
- Novolog: 240 reports
- Nystatin: 134 reports
- Ocrevus: 126 reports
- Omeprazole: 2,033 reports
- Ondansetron: 206 reports
- Opdivo: 129 reports
- Orencia: 1,430 reports
- Otezla: 19,845 reports
- Oxybutynin: 110 reports
- Oxycodone: 503 reports
- Oxycontin: 214 reports
- Pantoprazole: 1,427 reports
- Pantoprazole sodium: 250 reports
- Paracetamol: 369 reports
- Paroxetine: 180 reports
- Paxil: 215 reports
- Pegasys: 214 reports
- Pentasa: 125 reports
- Pepcid: 111 reports
- Percocet: 271 reports
- Plaquenil: 736 reports
- Plavix: 378 reports
- Potassium: 316 reports
- Prednisolone: 411 reports
- Prednisone: 4,329 reports
- Pregabalin: 262 reports
- Premarin: 256 reports
- Prevacid: 290 reports
- Prilosec: 554 reports
- Proair hfa: 232 reports
- Probiotic: 168 reports
- Profen: 1,567 reports
- Progesterone: 143 reports
- Prolia: 194 reports
- Promethazine: 148 reports
- Protonix: 324 reports
- Protopic: 250 reports
- Prozac: 359 reports
- Q10: 142 reports
- Quetiapine fumarate: 133 reports
- Rabeprazole: 163 reports
- Ramipril: 661 reports
- Ranitidine: 436 reports
- Raptiva: 622 reports
- Remicade: 3,500 reports
- Revlimid: 161 reports
- Ribavirin: 245 reports
- Risperdal: 134 reports
- Rituxan: 426 reports
- Rosuvastatin calcium: 287 reports
- Sandostatin: 110 reports
- Senna: 135 reports
- Seroquel: 300 reports
- Sertraline: 709 reports
- Sertraline hydrochloride: 143 reports
- Simponi: 1,026 reports
- Simvastatin: 1,318 reports
- Singulair: 643 reports
- Skyrizi: 973 reports
- Soriatane: 594 reports
- Spiriva: 323 reports
- Spironolactone: 409 reports
- Stelara: 6,001 reports
- Sulfasalazine: 1,883 reports
- Sumatriptan: 136 reports
- Symbicort: 442 reports
- Synthroid: 1,526 reports
- Taclonex: 247 reports
- Tacrolimus: 217 reports
- Taltz: 1,728 reports
- Tamsulosin: 249 reports
- Tecfidera: 119 reports
- Telmisartan: 103 reports
- Temaz: 232 reports
- Temazepam: 228 reports
- Topamax: 161 reports
- Topiramate: 213 reports
- Toprol-xl: 118 reports
- Tramadol: 1,101 reports
- Tremfya: 1,065 reports
- Triamcinolone: 1,018 reports
- Triamcinolone acetonide: 463 reports
- Tricor: 121 reports
- Trulicity: 110 reports
- Turmeric: 113 reports
- Tylenol: 1,054 reports
- Tysabri: 197 reports
- Ultram: 105 reports
- Valacyclovir: 127 reports
- Valium: 165 reports
- Valsartan: 302 reports
- Valtrex: 131 reports
- Ventolin: 217 reports
- Vicodin: 223 reports
- Victoza: 149 reports
- Vioxx: 177 reports
- Vitamin b12: 741 reports
- Vitamin c: 556 reports
- Vitamin d: 1,949 reports
- Vitamin d3: 643 reports
- Vitamin e: 200 reports
- Vitamins: 555 reports
- Voltaren: 339 reports
- Warfarin sodium: 109 reports
- Wellbutrin: 622 reports
- Xanax: 573 reports
- Xarelto: 194 reports
- Xeljanz: 1,511 reports
- Xeljanz xr: 603 reports
- Xolair: 226 reports
- Zantac: 264 reports
- Zetia: 134 reports
- Zide: 1,093 reports
- Zocor: 279 reports
- Zofran: 161 reports
- Zoloft: 506 reports
- Zolpidem: 424 reports
- Zometa: 167 reports
- Zopiclone: 232 reports
- Zyprexa: 115 reports
- Zyrtec: 539 reports
All the drugs that are associated with Psoriasis:
- Psoriasis (2,266 drugs)
Common conditions associated with Psoriasis:
- Abnormal heart rhythms: 129 reports
- Acid reflux: 983 reports
- Acupuncture and pain: 944 reports
- A-fib: 198 reports
- Agrypnia: 573 reports
- Alternative medicine - pain relief: 1,902 reports
- Anaemia: 145 reports
- Angina pectoris: 127 reports
- Angina - stable: 127 reports
- Ankylosing spondylitis: 1,512 reports
- Anticoagulant therapy: 200 reports
- Antidepressant therapy: 1,577 reports
- Anxiety: 1,082 reports
- Anxiety aggravated: 1,084 reports
- Anxiety and stress: 1,082 reports
- Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension: 1,082 reports
- Anxiolytic therapy: 1,082 reports
- Arrhythmia: 129 reports
- Arrhythmias: 129 reports
- Arthralgia: 466 reports
- Arthritis: 685 reports
- Arthritis - osteoarthritis: 184 reports
- Asthma: 691 reports
- Atrial fibrillation: 198 reports
- Atrial fibrillation/flutter: 198 reports
- Back pain: 201 reports
- Bipolar: 178 reports
- Bi-polar: 178 reports
- Bipolar disorder: 178 reports
- Birth control: 289 reports
- Blood cholesterol abnormal: 1,864 reports
- Blood cholesterol increased: 1,864 reports
- Blood pressure abnormal: 512 reports
- Blood pressure - high: 3,540 reports
- Blood pressure increased: 3,540 reports
- Blood pressure management: 203 reports
- Blood triglycerides abnormal: 1,864 reports
- Blood triglycerides increased: 1,864 reports
- Bone and joint pain: 466 reports
- Bp: 203 reports
- Breast cancer: 130 reports
- Bronchial asthma: 689 reports
- Cancer - breast: 129 reports
- Can't sleep: 573 reports
- Cardiac disorder: 309 reports
- Cessation of smoking: 135 reports
- Chronic asthma: 689 reports
- Chronic obstructive airway disease: 189 reports
- Chronic obstructive pulmonary disease: 189 reports
- Colitis ulcerative: 765 reports
- Constipation: 165 reports
- Constipation aggravated: 165 reports
- Contraception: 289 reports
- Copd: 189 reports
- Crohns: 3,134 reports
- Crohn's disease: 3,134 reports
- Crohns disease: 3,134 reports
- Crohn's disease aggravated: 3,134 reports
- Depression: 1,579 reports
- Depression aggravated: 1,579 reports
- Diabetes: 1,349 reports
- Diabetes mellitus: 1,344 reports
- Diabetes mellitus management: 1,343 reports
- Diabetes mellitus non-insulin-dependent: 174 reports
- Diabetic type 2: 402 reports
- Djd: 184 reports
- Dm: 1,343 reports
- Dyslipidemia: 1,864 reports
- Dyspepsia: 295 reports
- Dysrhythmias: 129 reports
- Dyssomnia: 573 reports
- Eczema: 178 reports
- Eczema exacerbated: 178 reports
- Epilepsy: 102 reports
- Exercise-induced asthma: 689 reports
- Family planning and contraception: 289 reports
- Feeling uptight: 1,082 reports
- Fibromyalgia: 275 reports
- Fibromyalgia syndrome: 275 reports
- Fibrositis: 275 reports
- Fluid retention: 153 reports
- Frequent headaches: 153 reports
- Gastric disorder: 170 reports
- Gastroesophageal reflux disease: 983 reports
- Gastro-oesophageal reflux disease: 983 reports
- Gastrooesophageal reflux disease: 983 reports
- General physical condition: 581 reports
- Gerd: 983 reports
- Gout: 207 reports
- Granulomatous ileocolitis: 3,134 reports
- Guttate psoriasis: 134 reports
- Hbp: 3,540 reports
- Headache: 154 reports
- Headaches: 153 reports
- Healthy living: 581 reports
- Heartburn: 983 reports
- Hepatitis c: 351 reports
- Herpes zoster: 203 reports
- Hidradenitis: 241 reports
- High blood cholesterol: 1,864 reports
- High blood cholesterol and triglycerides: 1,864 reports
- High blood pressure: 3,540 reports
- High cholesterol: 1,864 reports
- Hormone replacement therapy: 143 reports
- Hormone therapy: 143 reports
- Hrt: 143 reports
- Htn: 3,540 reports
- Hypercholesterolaemia: 1,864 reports
- Hypercholesterolemia: 1,864 reports
- Hyperlipidaemia: 170 reports
- Hyperlipidemia: 1,864 reports
- Hypersensitivity: 403 reports
- Hypertension: 3,552 reports
- Hypnosis and pain: 1,902 reports
- Hypothyroid: 737 reports
- Hypothyroidism: 737 reports
- Ileitis: 3,134 reports
- Indigestion: 295 reports
- Inflammatory bowel disease - crohn's disease: 3,134 reports
- Insomnia: 573 reports
- Itchiness: 301 reports
- Itching: 301 reports
- Jitters: 1,082 reports
- Joint pain: 466 reports
- Jra: 720 reports
- Juvenile rheumatoid arthritis: 720 reports
- Lipid profile: 1,087 reports
- Low thyroid: 737 reports
- Migraine: 408 reports
- Migraines: 408 reports
- Mineral supplementation: 159 reports
- Ms: 817 reports
- Ms hug: 817 reports
- Multiple myeloma: 179 reports
- Multiple sclerosis: 817 reports
- Muscle spasm: 197 reports
- Muscle spasms: 197 reports
- Myxedema: 737 reports
- Narcolepsy: 124 reports
- Nausea: 134 reports
- Nerve pain: 143 reports
- Neuralgia: 143 reports
- Niddm: 402 reports
- Oa: 184 reports
- Osteoarthritis: 184 reports
- Osteoarthrosis: 184 reports
- Osteopenia: 135 reports
- Osteoporosis: 567 reports
- Pain: 1,905 reports
- Pain in extremity: 136 reports
- Pain - joints: 466 reports
- Pain management: 1,902 reports
- Pain relief: 1,902 reports
- Panic attack: 114 reports
- Panic disorder: 114 reports
- Plaque psoriasis: 58,726 reports
- Pregnancy: 289 reports
- Preventive health care: 271 reports
- Pruritus: 303 reports
- Psoriasis: 63,224 reports
- Psoriasis aggravated: 41,046 reports
- Psoriasis - guttate: 134 reports
- Psoriatic arthropathy: 22,682 reports
- Psoriatic arthropathy aggravated: 22,682 reports
- Pustular psoriasis: 384 reports
- Quit smoking: 135 reports
- Ra: 6,377 reports
- Rashes: 126 reports
- Reduce cholesterol: 1,128 reports
- Reflux: 983 reports
- Regional enteritis: 3,134 reports
- Restless leg: 134 reports
- Restless leg syndrome: 134 reports
- Rheumatoid arthritis: 6,377 reports
- Rheumatoid spondylitis: 1,512 reports
- Seasonal allergy: 248 reports
- Sleep aid: 573 reports
- Sleep disorder: 379 reports
- Sleep disorder due to general medical condition, insomnia type: 379 reports
- Sleep disorders: 379 reports
- Sleep disorder therapy: 379 reports
- Sleep issues: 573 reports
- Sleeplessness: 573 reports
- Smoking and smokeless tobacco: 135 reports
- Smoking cessation therapy: 135 reports
- Spondylitis: 1,512 reports
- Stable angina: 127 reports
- Stop smoking: 135 reports
- Stress: 1,082 reports
- Stress and anxiety: 1,082 reports
- Supplementation therapy: 316 reports
- Tachycardia aggravated: 129 reports
- Tension: 1,082 reports
- Thrombosis: 139 reports
- Thyroid: 176 reports
- Thyroid diseases: 289 reports
- Thyroid disorder: 289 reports
- Thyroide: 289 reports
- Tobacco abuse: 135 reports
- Tobacco user: 135 reports
- Type 2 diabetes: 402 reports
- Type 2 diabetes mellitus: 402 reports
- Uc: 765 reports
- Ulcerative colitis: 765 reports
- Uncomfortable fullness after meals: 295 reports
- Under active thyroid: 737 reports
- Underactive thyroid: 737 reports
- Under active thyroids: 737 reports
- Vitamin supplementation: 581 reports
- Wakefulness: 573 reports
- Water retention: 153 reports
All the conditions that are associated with Psoriasis:
- Psoriasis (1,580 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote) and Depakote (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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