Depakote and Pulmonary artery stenosis congenital - a phase IV clinical study of FDA data

Summary:

We study 51,553 people who have side effects when taking Depakote. Pulmonary artery stenosis congenital is found, especially among people who are female, 0-1 old, have been taking the drug for 1 - 6 months, also take Paxil and have Asthma.

The phase IV clinical study analyzes which people take Depakote and have Pulmonary artery stenosis congenital. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 21, 2023

51,553 people reported to have side effects when taking Depakote.
Among them, 22 people (0.04%) have Pulmonary artery stenosis congenital.

What is Depakote?

Depakote has active ingredients of divalproex sodium. It is used in bipolar disorder. Currently, eHealthMe is studying from 54,479 Depakote users.

What is Pulmonary artery stenosis congenital?

Pulmonary artery stenosis congenital (congenital -narrowing (stenosis) that occurs in the lung artery) is found to be associated with 320 drugs and 175 conditions by eHealthMe. Currently, we are studying 1,235 people who have Pulmonary artery stenosis congenital.

Number of Depakote and Pulmonary artery stenosis congenital reports submitted per year:

Could Depakote cause Pulmonary artery stenosis congenital?

Time on Depakote when people have Pulmonary artery stenosis congenital *:

Gender of people who have Pulmonary artery stenosis congenital when taking Depakote *:

female: 63.64 %
male: 36.36 %

Age of people who have Pulmonary artery stenosis congenital when taking Depakote *:

Common drugs people take besides Depakote *:

Common side effects people have besides Pulmonary artery stenosis congenital *:

Cardiac Murmur (an heart sound in valve abnormality): 19 people, 86.36%
Drug Exposure During Pregnancy: 17 people, 77.27%
Pulmonary Artery Stenosis (narrowing (stenosis) that occurs in the lung artery): 10 people, 45.45%
Foetal Distress Syndrome (altered heart rate or rhythm and leading tocompromised blood flow or changes in blood chemistry of foetus): 10 people, 45.45%
Respiratory Distress (difficulty in breathing): 10 people, 45.45%
Aortic Disorder: 9 people, 40.91%
Liver Disorder (liver diseases): 9 people, 40.91%
Intraventricular Haemorrhage (intraventricular bleeding): 9 people, 40.91%
Cns Ventriculitis (inflammation of the ventricles in the brain): 9 people, 40.91%
Hypotension (abnormally low blood pressure): 9 people, 40.91%

Common conditions people have *:

Stress And Anxiety: 13 people, 59.09%
Infection: 13 people, 59.09%
Depression: 13 people, 59.09%
Asthma: 13 people, 59.09%
Sleep Disorder: 9 people, 40.91%
Nausea (feeling of having an urge to vomit): 9 people, 40.91%
Migraine (headache): 9 people, 40.91%
Insomnia (sleeplessness): 4 people, 18.18%
Birth Control: 3 people, 13.64%
Drug Exposure During Pregnancy: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Depakote and have Pulmonary artery stenosis congenital?

Check whether Pulmonary artery stenosis congenital is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Depakote side effects by duration, gender and age:

Depakote side effects (54,479 reports)

Pulmonary artery stenosis congenital treatments and more:

Pulmonary artery stenosis congenital (1,235 reports)

Common drugs associated with Pulmonary artery stenosis congenital:

Paxil: 483 reports
Zofran: 186 reports
Vitamins: 169 reports
Paxil cr: 133 reports
Zoloft: 131 reports

All the drugs that are associated with Pulmonary artery stenosis congenital:

Pulmonary artery stenosis congenital (320 drugs)

Common conditions associated with Pulmonary artery stenosis congenital:

Depression: 337 reports
Stress and anxiety: 144 reports

All the conditions that are associated with Pulmonary artery stenosis congenital:

Pulmonary artery stenosis congenital (175 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote) and Depakote (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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