Depakote and Weight increased - a phase IV clinical study of FDA data
Summary:
We study 51,553 people who have side effects when taking Depakote. Weight increased is found, especially among people who are female, 40-49 old, have been taking the drug for 2 - 5 years, also take Zyprexa and have Depression.
The phase IV clinical study analyzes which people take Depakote and have Weight increased. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
What are phase IV trials?
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
51,553 people reported to have side effects when taking Depakote.
Among them, 2,816 people (5.46%) have Weight increased.
What is Depakote?
Depakote has active ingredients of divalproex sodium. It is used in bipolar disorder. Currently, eHealthMe is studying from 54,472 Depakote users.
What is Weight increased?
Weight increased is found to be associated with 4,026 drugs and 3,817 conditions by eHealthMe. Currently, we are studying 263,263 people who have Weight increased.
Number of Depakote and Weight increased reports submitted per year:

Time on Depakote when people have Weight increased *:
Gender of people who have Weight increased when taking Depakote*:
Age of people who have Weight increased when taking Depakote *:
Common drugs people take besides Depakote *:
Common side effects people have besides Weight increased *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Depakote and have Weight increased?
Check whether Weight increased is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Weight increased and when was it recovered:
Expand to all the drugs that have ingredients of divalproex sodium:
- Weight increased and drugs with ingredients of divalproex sodium (3,263 reports)
Alternative drugs to, pros and cons of Depakote:
- Depakote (54,472 reports)
Browse all side effects of Depakote:
a b c d e f g h i j k l m n o p q r s t u v w x y zWeight increased treatments and more:
- Weight increased (263,263 reports)
Common drugs associated with Weight increased:
- Prednisone: 18,993 reports
- Methotrexate: 14,612 reports
- Lyrica: 12,245 reports
- Humira: 9,485 reports
- Risperdal: 9,118 reports
- Aspirin: 8,715 reports
- Pantoprazole: 8,474 reports
- Metformin: 7,862 reports
- Synthroid: 7,760 reports
- Vitamin d: 6,827 reports
All the drugs that are associated with Weight increased:
- Weight increased (4,026 drugs)
Common conditions associated with Weight increased:
- Rheumatoid arthritis: 18,769 reports
- Depression: 10,701 reports
- High blood pressure: 9,128 reports
- Pain: 7,919 reports
- Crohn's disease: 7,365 reports
- Asthma: 6,992 reports
All the conditions that are associated with Weight increased:
- Weight increased (3,817 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on divalproex sodium (the active ingredients of Depakote) and Depakote (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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