Depo-provera and Nail ridging - a phase IV clinical study of FDA data
Summary:
Nail ridging is reported only by a few people who take Depo-Provera.
The phase IV clinical study analyzes which people take Depo-provera and have Nail ridging. It is created by eHealthMe based on reports of 14,619 people who have side effects while taking Depo-provera from the FDA, and is updated regularly.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
14,619 people reported to have side effects when taking Depo-provera.
Among them, 1 person (0.01%) has Nail ridging.
What is Depo-provera?
Depo-provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 15,873 Depo-provera users for its effectiveness, alternative drugs and more.
What is Nail ridging?
Nail ridging (nail has raised ridges and is thin and curved inward) is found to be associated with 426 drugs and 283 conditions by eHealthMe.
Number of Depo-provera and Nail ridging reports submitted per year:

Gender of people who have Nail ridging when taking Depo-provera *:
- female: 100 %
- male: 0.0 %
Age of people who have Nail ridging when taking Depo-provera *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 100 %
- 40-49: 0.0 %
- 50-59: 0.0 %
- 60+: 0.0 %
Common side effects people have besides Nail ridging *:
- Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 1 person, 100.00%
- Hair Loss: 1 person, 100.00%
- Amenorrhea (absence of a menstrual period in a woman of reproductive age): 1 person, 100.00%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 1 person, 100.00%
- Bone Loss: 1 person, 100.00%
- Confusional State: 1 person, 100.00%
- Depression: 1 person, 100.00%
- Fainting (loss of consciousness and postural tone): 1 person, 100.00%
- Fatigue (feeling of tiredness): 1 person, 100.00%
- Hair Growth Abnormal: 1 person, 100.00%
* Approximation only. Some reports may have incomplete information.
Do you take Depo-provera and have Nail ridging?
Check whether Nail ridging is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
Related studies
How severe was Nail ridging and when was it recovered:
Expand to all the drugs that have ingredients of medroxyprogesterone acetate:
Alternative drugs to, pros and cons of Depo-provera:
- Depo-provera (15,873 reports)
Common Depo-provera side effects:
- Weight increased: 1,079 reports
- Depression: 996 reports
- Drug ineffective: 945 reports
- Amenorrhea (absence of a menstrual period in a woman of reproductive age): 872 reports
- Headache (pain in head): 819 reports
- Pain: 761 reports
- Fatigue (feeling of tiredness): 726 reports
Browse all side effects of Depo-provera:
a b c d e f g h i j k l m n o p q r s t u v w x y zNail ridging treatments and more:
- Nail ridging (424 reports)
COVID vaccines that are related to Nail ridging:
- Nail ridging in Moderna COVID Vaccine
- Nail ridging in Pfizer BioNTech Covid Vaccine
- Nail ridging in Johnson and Johnson Covid Vaccine
All the drugs that are associated with Nail ridging:
- Nail ridging (426 drugs)
All the conditions that are associated with Nail ridging:
- Nail ridging (283 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on medroxyprogesterone acetate (the active ingredients of Depo-provera) and Depo-provera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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