Desflurane and Renal impairment - a phase IV clinical study of FDA data

Summary:

Renal impairment is found among people who take Desflurane, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Desflurane and have Renal impairment. It is created by eHealthMe based on reports of 1,143 people who have side effects when taking Desflurane from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Aug, 19, 2022

1,143 people reported to have side effects when taking Desflurane.
Among them, 18 people (1.57%) have Renal impairment.


What is Desflurane?

Desflurane has active ingredients of desflurane. eHealthMe is studying from 1,086 Desflurane users for its effectiveness, alternative drugs and more.

What is Renal impairment?

Renal impairment (severely reduced kidney function) is found to be associated with 2,525 drugs and 2,304 conditions by eHealthMe.

Number of Desflurane and Renal impairment reports submitted per year:

Could Desflurane cause Renal impairment?

Time on Desflurane when people have Renal impairment *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Renal impairment when taking Desflurane *:

  • female: 47.06 %
  • male: 52.94 %

Age of people who have Renal impairment when taking Desflurane *:

  • 0-1: 5.88 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 5.88 %
  • 30-39: 5.88 %
  • 40-49: 0.0 %
  • 50-59: 11.76 %
  • 60+: 70.59 %

Common drugs people take besides Desflurane *:

  1. Fentanyl: 7 people, 38.89%
  2. Lasix: 6 people, 33.33%
  3. Nitroglycerin: 5 people, 27.78%
  4. Heparin: 4 people, 22.22%
  5. Versed: 4 people, 22.22%
  6. Trasylol: 4 people, 22.22%
  7. Propofol: 4 people, 22.22%
  8. Protamine Sulfate: 3 people, 16.67%
  9. Dantrolene Sodium: 3 people, 16.67%
  10. Lisinopril: 3 people, 16.67%

Common side effects people have besides Renal impairment *:

  1. Hyperkalemia (damage to or disease of the kidney): 9 people, 50.00%
  2. Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 9 people, 50.00%
  3. Hypotension (abnormally low blood pressure): 8 people, 44.44%
  4. Aspartate Aminotransferase Increased: 8 people, 44.44%
  5. Blood Creatine Phosphokinase Increased: 8 people, 44.44%
  6. Body Temperature Increased: 8 people, 44.44%
  7. Drowsiness: 8 people, 44.44%
  8. Eye Movements - Uncontrollable: 8 people, 44.44%
  9. Neurological Decompensation (inability of brain to maintain proper function): 8 people, 44.44%
  10. Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 8 people, 44.44%

Common conditions people have *:

  1. Vasoplegia Syndrome (low systemic vascular resistance): 9 people, 50.00%
  2. Depression: 8 people, 44.44%
  3. Hypotension (abnormally low blood pressure): 4 people, 22.22%
  4. Sedation: 3 people, 16.67%
  5. Hyperthermia Malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions): 3 people, 16.67%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.56%
  7. Procedural Pain: 1 person, 5.56%
  8. High Blood Cholesterol: 1 person, 5.56%
  9. Anaesthesia: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Desflurane and have Renal impairment?

Check whether Renal impairment is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



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How severe was Renal impairment and when was it recovered:

Expand to all the drugs that have ingredients of desflurane:

Alternative drugs to, pros and cons of Desflurane:

Renal impairment treatments and more:

COVID vaccines that are related to Renal impairment:

Common drugs associated with Renal impairment:

All the drugs that are associated with Renal impairment:

Common conditions associated with Renal impairment:

All the conditions that are associated with Renal impairment:

How the study uses the data?

The study uses data from the FDA. It is based on desflurane (the active ingredients of Desflurane) and Desflurane (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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