Desyrel and Dupuytren's contracture - a phase IV clinical study of FDA data
Summary:
Dupuytren's contracture is found among people who take Desyrel, especially for people who are male, 50-59 old.
The phase IV clinical study analyzes which people take Desyrel and have Dupuytren's contracture. It is created by eHealthMe based on reports of 5,609 people who have side effects when taking Desyrel from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
5,609 people reported to have side effects when taking Desyrel.
Among them, 6 people (0.11%) have Dupuytren's contracture.
What is Desyrel?
Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 5,873 Desyrel users for its effectiveness, alternative drugs and more.
What is Dupuytren's contracture?
Dupuytren's contracture (thickening of the fibrous tissue layer underneath the skin of the palm and fingers) is found to be associated with 445 drugs and 208 conditions by eHealthMe.
Number of Desyrel and Dupuytren's contracture reports submitted per year:
Gender of people who have Dupuytren's contracture when taking Desyrel *:
- female: 0.0 %
- male: 100 %
Age of people who have Dupuytren's contracture when taking Desyrel *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 83.33 %
- 60+: 16.67 %
Common drugs people take besides Desyrel *:
- Zometa: 6 people, 100.00%
- Lisinopril: 6 people, 100.00%
- Ambien: 6 people, 100.00%
- Taxotere: 6 people, 100.00%
- Casodex: 6 people, 100.00%
- Leuprolide Acetate: 6 people, 100.00%
- Plavix: 6 people, 100.00%
- Oxycontin: 6 people, 100.00%
- Neupogen: 6 people, 100.00%
- Motrin: 6 people, 100.00%
Common side effects people have besides Dupuytren's contracture *:
- Activities Of Daily Living Impaired: 6 people, 100.00%
- Haemochromatosis (body to absorb more iron than usual from food): 6 people, 100.00%
- Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 6 people, 100.00%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 6 people, 100.00%
- Breathing Difficulty: 6 people, 100.00%
- Injury: 6 people, 100.00%
- Hypotension (abnormally low blood pressure): 6 people, 100.00%
- Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 6 people, 100.00%
- Herpes Simplex (herpes simplex is a common viral infection): 6 people, 100.00%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 6 people, 100.00%
Common conditions people have *:
- Bone Density Decreased: 5 people, 83.33%
- Metastases To Bone (cancer spreads to bone): 1 person, 16.67%
- Colon Cancer: 1 person, 16.67%
- Bone Loss: 1 person, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Desyrel and have Dupuytren's contracture?
Check whether Dupuytren's contracture is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Dupuytren's contracture and when was it recovered:
Expand to all the drugs that have ingredients of trazodone hydrochloride:
Alternative drugs to, pros and cons of Desyrel:
- Desyrel (5,873 reports)
Common Desyrel side effects:
- Abdominal pain: 167 reports
- Abdominal pain upper: 120 reports
- Acute kidney failure: 105 reports
- Agitation (state of anxiety or nervous excitement): 110 reports
- Anaemia (lack of blood): 169 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 148 reports
- Arrhythmias (irregular heartbeat): 119 reports
- Back pain: 214 reports
- Breathing difficulty: 360 reports
- Chest pain: 252 reports
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 111 reports
- Confusional state: 163 reports
- Constipation: 167 reports
- Cough: 197 reports
- Death: 113 reports
- Dehydration (dryness resulting from the removal of water): 121 reports
- Depression: 390 reports
- Diabetes: 165 reports
- Diarrhea: 337 reports
- Dizziness: 306 reports
- Drowsiness: 160 reports
- Drug dependence: 118 reports
- Drug ineffective: 375 reports
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 117 reports
- Fainting (loss of consciousness and postural tone): 141 reports
- Fall: 329 reports
- Fatigue (feeling of tiredness): 403 reports
- Fever: 315 reports
- Gait disturbance: 134 reports
- Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 112 reports
- Headache (pain in head): 309 reports
- High blood cholesterol: 124 reports
- High blood pressure: 231 reports
- Hypoaesthesia (reduced sense of touch or sensation): 167 reports
- Hypokalemia (low potassium): 112 reports
- Hypotension (abnormally low blood pressure): 192 reports
- Insomnia (sleeplessness): 294 reports
- Itching: 103 reports
- Joint pain: 179 reports
- Loss of consciousness: 123 reports
- Malaise (a feeling of general discomfort or uneasiness): 188 reports
- Memory loss: 166 reports
- Muscle spasms (muscle contraction): 121 reports
- Nausea (feeling of having an urge to vomit): 487 reports
- Nausea and vomiting: 269 reports
- Oedema peripheral (superficial swelling): 162 reports
- Pain: 365 reports
- Pain in extremity: 209 reports
- Pneumonia: 238 reports
- Pulmonary embolism (blockage of the main artery of the lung): 111 reports
- Rashes (redness): 209 reports
- Stress and anxiety: 364 reports
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 109 reports
- Suicidal ideation: 183 reports
- Suicide attempt: 108 reports
- Swallowing difficulty: 101 reports
- Thrombocytopenia (decrease of platelets in blood): 129 reports
- Tremor (trembling or shaking movements in one or more parts of your body): 197 reports
- Type 2 diabetes: 117 reports
- Urinary tract infection: 156 reports
- Vision blurred: 105 reports
- Weakness: 362 reports
- Weight decreased: 202 reports
- Weight increased: 194 reports
Browse all side effects of Desyrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zDupuytren's contracture treatments and more:
- Dupuytren's contracture (2,031 reports)
COVID vaccines that are related to Dupuytren's contracture:
- Dupuytren's contracture in Moderna COVID Vaccine
- Dupuytren's contracture in Pfizer BioNTech Covid Vaccine
- Dupuytren's contracture in Johnson and Johnson Covid Vaccine
Common drugs associated with Dupuytren's contracture:
- Xiaflex: 137 reports
All the drugs that are associated with Dupuytren's contracture:
- Dupuytren's contracture (445 drugs)
Common conditions associated with Dupuytren's contracture:
- Ra: 104 reports
All the conditions that are associated with Dupuytren's contracture:
- Dupuytren's contracture (208 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on trazodone hydrochloride (the active ingredients of Desyrel) and Desyrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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