Dexamethasone and Anaesthetic complication - a phase IV clinical study of FDA data


We study 139,222 people who have side effects when taking Dexamethasone. Anaesthetic complication is found, especially among people who are male, 50-59 old, have been taking the drug for < 1 month, also take Propofol and have Anaesthesia.

The phase IV clinical study analyzes which people take Dexamethasone and have Anaesthetic complication. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2023

139,222 people reported to have side effects when taking Dexamethasone.
Among them, 36 people (0.03%) have Anaesthetic complication.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is used in multiple myeloma. Currently, eHealthMe is studying from 139,876 Dexamethasone users.

What is Anaesthetic complication?

Anaesthetic complication is found to be associated with 795 drugs and 369 conditions by eHealthMe. Currently, we are studying 2,782 people who have Anaesthetic complication.

Number of Dexamethasone and Anaesthetic complication reports submitted per year:

Could Dexamethasone cause Anaesthetic complication?

Time on Dexamethasone when people have Anaesthetic complication *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Anaesthetic complication when taking Dexamethasone *:

  • female: 41.18 %
  • male: 58.82 %

Age of people who have Anaesthetic complication when taking Dexamethasone *:

  • 0-1: 0.0 %
  • 2-9: 23.53 %
  • 10-19: 8.82 %
  • 20-29: 2.94 %
  • 30-39: 5.88 %
  • 40-49: 2.94 %
  • 50-59: 35.29 %
  • 60+: 20.59 %

Common drugs people take besides Dexamethasone *:

  1. Propofol: 22 people, 61.11%
  2. Fentanyl: 13 people, 36.11%
  3. Isoflurane: 7 people, 19.44%
  4. Lidocaine: 6 people, 16.67%
  5. Sevoflurane: 6 people, 16.67%
  6. Cefazolin: 6 people, 16.67%
  7. Ketoprofen: 6 people, 16.67%
  8. Acetaminophen: 6 people, 16.67%
  9. Ondansetron: 5 people, 13.89%
  10. Glycopyrrolate: 5 people, 13.89%

Common side effects people have besides Anaesthetic complication *:

  1. High Blood Pressure: 8 people, 22.22%
  2. Weakness: 5 people, 13.89%
  3. Dyskinesia (abnormality or impairment of voluntary movement): 5 people, 13.89%
  4. Hypotension (abnormally low blood pressure): 4 people, 11.11%
  5. Po2 Decreased: 4 people, 11.11%
  6. Sinusitis (inflammation of sinus): 3 people, 8.33%
  7. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 8.33%
  8. Hemiparesis (weakness on one side of the body): 3 people, 8.33%
  9. Fungal Infection: 3 people, 8.33%
  10. Drug Ineffective: 3 people, 8.33%

Common conditions people have *:

  1. Anaesthesia: 10 people, 27.78%
  2. Local Anaesthesia: 4 people, 11.11%
  3. General Anaesthesia: 4 people, 11.11%
  4. Perioperative Analgesia: 3 people, 8.33%
  5. Neuromuscular Blockade: 3 people, 8.33%
  6. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 8.33%
  7. Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 2 people, 5.56%
  8. Wheezing (a high-pitched whistling sound made while you breath): 1 person, 2.78%
  9. Stiff-Man Syndrome (a rare disease of severe progressive muscle stiffness of the spine and lower extremities): 1 person, 2.78%
  10. Sacroiliitis (an inflammation of the sacroiliac joint): 1 person, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Dexamethasone and have Anaesthetic complication?

Check whether Anaesthetic complication is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Dexamethasone side effects by duration, gender and age:

Anaesthetic complication treatments and more:

Common drugs associated with Anaesthetic complication:

All the drugs that are associated with Anaesthetic complication:

Common conditions associated with Anaesthetic complication:

All the conditions that are associated with Anaesthetic complication:

How the study uses the data?

The study uses data from the FDA. It is based on dexamethasone (the active ingredients of Dexamethasone) and Dexamethasone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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