Dexamethasone and Central nervous system lymphoma - a phase IV clinical study of FDA data

Summary:

Central nervous system lymphoma is found among people who take Dexamethasone, especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months.

The phase IV clinical study analyzes which people take Dexamethasone and have Central nervous system lymphoma. It is created by eHealthMe based on reports of 105,970 people who have side effects when taking Dexamethasone from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 28, 2023

105,970 people reported to have side effects when taking Dexamethasone.
Among them, 40 people (0.04%) have Central nervous system lymphoma.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 106,613 Dexamethasone users for its effectiveness, alternative drugs and more.

What is Central nervous system lymphoma?

Central nervous system lymphoma (cancer of central nervous system forms in lymph tissue) is found to be associated with 420 drugs and 187 conditions by eHealthMe.

Number of Dexamethasone and Central nervous system lymphoma reports submitted per year:

Could Dexamethasone cause Central nervous system lymphoma?

Time on Dexamethasone when people have Central nervous system lymphoma *:

Gender of people who have Central nervous system lymphoma when taking Dexamethasone *:

female: 50 %
male: 50 %

Age of people who have Central nervous system lymphoma when taking Dexamethasone *:

Common drugs people take besides Dexamethasone *:

Common side effects people have besides Central nervous system lymphoma *:

Nausea And Vomiting: 11 people, 27.50%
Death: 10 people, 25.00%
Nausea (feeling of having an urge to vomit): 10 people, 25.00%
Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 9 people, 22.50%
Metastases To Lung (cancer spreads to lung): 8 people, 20.00%
Diarrhea: 8 people, 20.00%
Headache (pain in head): 8 people, 20.00%
Metastases To Spleen (cancer spreads to spleen): 8 people, 20.00%
Urinary Tract Infection: 8 people, 20.00%
Fatigue (feeling of tiredness): 8 people, 20.00%

Common conditions people have *:

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 7 people, 17.50%
Pain: 3 people, 7.50%
B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 2 people, 5.00%
Burkitt's Lymphoma (cancer of the lymphatic system): 2 people, 5.00%
Diffuse Large B-Cell Lymphoma Refractory (cancer of b cells, a type of white blood cell-relapsed): 2 people, 5.00%
Wegener's Granulomatosis (inflammation of the blood vessels lungs sinuses): 1 person, 2.50%
Diffuse Large B-Cell Lymphoma Recurrent (recurrent cancer of b cells, a type of white blood cell): 1 person, 2.50%
Brain Neoplasm (tumour of brain): 1 person, 2.50%
Burkitt's Leukaemia (blood cancer): 1 person, 2.50%
Burkitt's Lymphoma Stage Iv (blood cancer stage iv): 1 person, 2.50%

* Approximation only. Some reports may have incomplete information.

Do you take Dexamethasone and have Central nervous system lymphoma?

Check whether Central nervous system lymphoma is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .

Related studies

How severe was Central nervous system lymphoma and when was it recovered:

Central nervous system lymphoma in Dexamethasone

Expand to all the drugs that have ingredients of dexamethasone:

Central nervous system lymphoma and drugs with ingredients of dexamethasone

Alternative drugs to, pros and cons of Dexamethasone:

Dexamethasone (106,613 reports)

Common Dexamethasone side effects:

Browse all side effects of Dexamethasone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Central nervous system lymphoma treatments and more:

Central nervous system lymphoma (3,780 reports)

COVID vaccines that are related to Central nervous system lymphoma:

Common drugs associated with Central nervous system lymphoma:

Methotrexate: 275 reports
Prednisone: 260 reports
Cyclophosphamide: 206 reports
Mycophenolate mofetil: 175 reports
Prednisolone: 138 reports

All the drugs that are associated with Central nervous system lymphoma:

Central nervous system lymphoma (420 drugs)

All the conditions that are associated with Central nervous system lymphoma:

Central nervous system lymphoma (187 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dexamethasone (the active ingredients of Dexamethasone) and Dexamethasone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.