Dexamethasone and Hypertensive crisis - a phase IV clinical study of FDA data

Summary:

Hypertensive crisis is found among people who take Dexamethasone, especially for people who are female, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Dexamethasone and have Hypertensive crisis. It is created by eHealthMe based on reports of 80,228 people who have side effects when taking Dexamethasone from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.



On Jun, 29, 2022

80,228 people reported to have side effects when taking Dexamethasone.
Among them, 94 people (0.12%) have Hypertensive crisis.


What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 80,835 Dexamethasone users for its effectiveness, alternative drugs and more.

What is Hypertensive crisis?

Hypertensive crisis is found to be associated with 1,207 drugs and 817 conditions by eHealthMe.

Number of Dexamethasone and Hypertensive crisis reports submitted per year:

Could Dexamethasone cause Hypertensive crisis?

Time on Dexamethasone when people have Hypertensive crisis *:

  • < 1 month: 84.85 %
  • 1 - 6 months: 6.06 %
  • 6 - 12 months: 6.06 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 3.03 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Hypertensive crisis when taking Dexamethasone *:

  • female: 80.49 %
  • male: 19.51 %

Age of people who have Hypertensive crisis when taking Dexamethasone *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.63 %
  • 20-29: 0.0 %
  • 30-39: 5.26 %
  • 40-49: 2.63 %
  • 50-59: 22.37 %
  • 60+: 67.11 %

Common drugs people take besides Dexamethasone *:

  1. Revlimid: 16 people, 17.02%
  2. Velcade: 13 people, 13.83%
  3. Allopurinol: 10 people, 10.64%
  4. Acyclovir: 8 people, 8.51%
  5. Aspirin: 8 people, 8.51%
  6. Lenalidomide: 7 people, 7.45%
  7. Calcium Gluconate: 7 people, 7.45%
  8. Neupogen: 7 people, 7.45%
  9. Zometa: 6 people, 6.38%
  10. Meropenem: 5 people, 5.32%

Common side effects people have besides Hypertensive crisis *:

  1. Thrombocytopenia (decrease of platelets in blood): 16 people, 17.02%
  2. Acute Pulmonary Oedema (sudden deposit of fluid in the lung)): 15 people, 15.96%
  3. Anaemia (lack of blood): 13 people, 13.83%
  4. Diarrhea: 11 people, 11.70%
  5. Breathing Difficulty: 10 people, 10.64%
  6. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 10 people, 10.64%
  7. Dizziness: 9 people, 9.57%
  8. Leukaemia Plasmacytic (a progressive, malignant disease of the blood-forming organs): 8 people, 8.51%
  9. Chest Pain: 7 people, 7.45%
  10. Fever: 7 people, 7.45%

Common conditions people have *:

  1. Diarrhea: 10 people, 10.64%
  2. Nausea (feeling of having an urge to vomit): 10 people, 10.64%
  3. High Blood Pressure: 9 people, 9.57%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 8 people, 8.51%
  5. Febrile Neutropenia (fever with reduced white blood cells): 7 people, 7.45%
  6. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 7.45%
  7. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 7 people, 7.45%
  8. Pleural Disorder: 7 people, 7.45%
  9. Leukaemia Plasmacytic (a progressive, malignant disease of the blood-forming organs): 7 people, 7.45%
  10. Bleeding Disorders: 7 people, 7.45%

* Approximation only. Some reports may have incomplete information.

Do you take Dexamethasone and have Hypertensive crisis?

Check whether Hypertensive crisis is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of Dexamethasone:

Hypertensive crisis treatments and more:

COVID vaccines that are related to Hypertensive crisis:

How severe was Hypertensive crisis and when was it recovered:

Expand to all the drugs that have ingredients of dexamethasone:

Common drugs associated with Hypertensive crisis:

All the drugs that are associated with Hypertensive crisis:

Common conditions associated with Hypertensive crisis:

All the conditions that are associated with Hypertensive crisis:

How the study uses the data?

The study uses data from the FDA. It is based on dexamethasone (the active ingredients of Dexamethasone) and Dexamethasone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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