Diclofenac and Gastrointestinal motility disorder - a phase IV clinical study of FDA data

Summary:

We study 36,069 people who have side effects when taking Diclofenac. Gastrointestinal motility disorder is found, especially among people who are female, 50-59 old, have been taking the drug for < 1 month, also take Pantoprazole and have Fibromyalgia.

The phase IV clinical study analyzes which people take Diclofenac and have Gastrointestinal motility disorder. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Sep, 25, 2023

36,069 people reported to have side effects when taking Diclofenac.
Among them, 22 people (0.06%) have Gastrointestinal motility disorder.


What is Diclofenac?

Diclofenac has active ingredients of diclofenac. Currently, eHealthMe is studying from 36,393 Diclofenac users.

What is Gastrointestinal motility disorder?

Gastrointestinal motility disorder (abnormal intestinal contractions) is found to be associated with 1,226 drugs and 679 conditions by eHealthMe. Currently, we are studying 7,272 people who have Gastrointestinal motility disorder.

Number of Diclofenac and Gastrointestinal motility disorder reports submitted per year:

Could Diclofenac cause Gastrointestinal motility disorder?

Time on Diclofenac when people have Gastrointestinal motility disorder *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Gastrointestinal motility disorder when taking Diclofenac *:

  • female: 77.27 %
  • male: 22.73 %

Age of people who have Gastrointestinal motility disorder when taking Diclofenac *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 60 %
  • 60+: 40 %

Common drugs people take besides Diclofenac *:

  1. Pantoprazole: 18 people, 81.82%
  2. Anafranil: 11 people, 50.00%
  3. Celebrex: 11 people, 50.00%
  4. Magnesium: 10 people, 45.45%
  5. Amlodipine: 5 people, 22.73%
  6. Ondansetron: 5 people, 22.73%
  7. Duspatal: 4 people, 18.18%
  8. Mirabegron: 3 people, 13.64%
  9. Letairis: 3 people, 13.64%
  10. Uptravi: 3 people, 13.64%

Common side effects people have besides Gastrointestinal motility disorder *:

  1. Fatigue (feeling of tiredness): 21 people, 95.45%
  2. Dizziness: 19 people, 86.36%
  3. Spinal Osteoarthritis (joint cartilage loss in spine): 16 people, 72.73%
  4. Pain In Extremity: 16 people, 72.73%
  5. Intervertebral Disc Protrusion (spinal disc protrusion): 16 people, 72.73%
  6. Joint Pain: 16 people, 72.73%
  7. Pain: 14 people, 63.64%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 14 people, 63.64%
  9. Peripheral Swelling: 14 people, 63.64%
  10. Diarrhea: 14 people, 63.64%

Common conditions people have *:

  1. Fibromyalgia (a long-term condition which causes pain all over the body): 16 people, 72.73%
  2. Pain: 11 people, 50.00%
  3. Myosclerosis (hardening of muscle tissue): 11 people, 50.00%
  4. Joint Pain: 7 people, 31.82%
  5. High Blood Pressure: 7 people, 31.82%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 27.27%
  7. Enlarged Prostate: 5 people, 22.73%
  8. Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 13.64%
  9. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 13.64%
  10. Idiopathic Thrombocytopenic Purpura (Itp) (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

Do you take Diclofenac and have Gastrointestinal motility disorder?

Check whether Gastrointestinal motility disorder is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Gastrointestinal motility disorder and when was it recovered:

Expand to all the drugs that have ingredients of diclofenac:

Alternative drugs to, pros and cons of Diclofenac:

Browse all side effects of Diclofenac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Gastrointestinal motility disorder treatments and more:

Common drugs associated with Gastrointestinal motility disorder:

All the drugs that are associated with Gastrointestinal motility disorder:

Common conditions associated with Gastrointestinal motility disorder:

All the conditions that are associated with Gastrointestinal motility disorder:

How the study uses the data?

The study uses data from the FDA. It is based on diclofenac (the active ingredients of Diclofenac) and Diclofenac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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