Diflunisal and Urticaria aggravated - a phase IV clinical study of FDA data

Summary:

Urticaria aggravated is found among people who take Diflunisal, especially for people who are female, 30-39 old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Diflunisal and have Urticaria aggravated. It is created by eHealthMe based on reports of 849 people who have side effects when taking Diflunisal from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Sep, 22, 2022

849 people reported to have side effects when taking Diflunisal.
Among them, 14 people (1.65%) have Urticaria aggravated.


What is Diflunisal?

Diflunisal has active ingredients of diflunisal. eHealthMe is studying from 866 Diflunisal users for its effectiveness, alternative drugs and more.

What is Urticaria aggravated?

Urticaria aggravated (aggravated rash of round, red welts on the skin that itch intensely) is found to be associated with 1,030 drugs and 401 conditions by eHealthMe.

Number of Diflunisal and Urticaria aggravated reports submitted per year:

Could Diflunisal cause Urticaria aggravated?

Time on Diflunisal when people have Urticaria aggravated *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Urticaria aggravated when taking Diflunisal *:

  • female: 53.85 %
  • male: 46.15 %

Age of people who have Urticaria aggravated when taking Diflunisal *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 50 %
  • 40-49: 10 %
  • 50-59: 20 %
  • 60+: 20 %

Common drugs people take besides Diflunisal *:

  1. Codeine: 4 people, 28.57%
  2. Demerol: 4 people, 28.57%
  3. Tegsedi: 4 people, 28.57%
  4. Gravol: 4 people, 28.57%
  5. Morphine: 3 people, 21.43%
  6. Diclofenac: 3 people, 21.43%
  7. Prilosec: 3 people, 21.43%
  8. Percocet: 3 people, 21.43%
  9. Voltaren: 2 people, 14.29%
  10. Dilaudid: 2 people, 14.29%

Common side effects people have besides Urticaria aggravated *:

  1. Nausea (feeling of having an urge to vomit): 8 people, 57.14%
  2. Fatigue (feeling of tiredness): 5 people, 35.71%
  3. Prealbumin Decreased: 4 people, 28.57%
  4. Drowsiness: 4 people, 28.57%
  5. Gastritis (inflammation of stomach): 4 people, 28.57%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 28.57%
  7. Vision Blurred: 4 people, 28.57%
  8. Migraine (headache): 4 people, 28.57%
  9. Nucleated Red Cells: 4 people, 28.57%
  10. Breath Odor: 4 people, 28.57%

Common conditions people have *:

  1. Hereditary Neuropathic Amyloidosis (hereditary- diseases resulting from abnormal deposition of certain proteins (amyloid) in various bodily areas by problems with signals from the nerves): 4 people, 28.57%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
  3. Micturition Urgency (urgency to pass the urine): 1 person, 7.14%
  4. Joint Pain: 1 person, 7.14%
  5. Hot Flush (sudden feelings of heat): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Diflunisal and have Urticaria aggravated?

Check whether Urticaria aggravated is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Urticaria aggravated and when was it recovered:

Expand to all the drugs that have ingredients of diflunisal:

Alternative drugs to, pros and cons of Diflunisal:

Urticaria aggravated treatments and more:

COVID vaccines that are related to Urticaria aggravated:

Common drugs associated with Urticaria aggravated:

All the drugs that are associated with Urticaria aggravated:

Common conditions associated with Urticaria aggravated:

All the conditions that are associated with Urticaria aggravated:

How the study uses the data?

The study uses data from the FDA. It is based on diflunisal (the active ingredients of Diflunisal) and Diflunisal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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