Digoxin and Testicular atrophy - a phase IV clinical study of FDA data


Testicular atrophy is found among people who take Digoxin, especially for people who are 60+ old, have been taking the drug for 5 - 10 years.

The phase IV clinical study analyzes which people take Digoxin and have Testicular atrophy. It is created by eHealthMe based on reports of 87,772 people who have side effects when taking Digoxin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 30, 2022

87,772 people reported to have side effects when taking Digoxin.
Among them, 10 people (0.01%) have Testicular atrophy.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 89,193 Digoxin users for its effectiveness, alternative drugs and more.

What is Testicular atrophy?

Testicular atrophy (wasting of testes) is found to be associated with 373 drugs and 184 conditions by eHealthMe.

Number of Digoxin and Testicular atrophy reports submitted per year:

Could Digoxin cause Testicular atrophy?

Time on Digoxin when people have Testicular atrophy *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

Age of people who have Testicular atrophy when taking Digoxin *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Digoxin *:

  1. Mitoxantrone: 9 people, 90.00%
  2. Plavix: 9 people, 90.00%
  3. Albuterol: 9 people, 90.00%
  4. Bextra: 9 people, 90.00%
  5. Clopidogrel: 9 people, 90.00%
  6. Crestor: 9 people, 90.00%
  7. Decadron: 9 people, 90.00%
  8. Diovan: 9 people, 90.00%
  9. Fosamax: 9 people, 90.00%
  10. Lipitor: 9 people, 90.00%

Common side effects people have besides Testicular atrophy *:

  1. Ejection Fraction Decreased (systolic heart failure): 10 people, 100.00%
  2. Anaemia (lack of blood): 10 people, 100.00%
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints): 10 people, 100.00%
  4. Back Pain: 10 people, 100.00%
  5. Headache (pain in head): 10 people, 100.00%
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 10 people, 100.00%
  7. Jaw Disorder (jaw disease): 9 people, 90.00%
  8. Osteomyelitis (infection of bone): 9 people, 90.00%
  9. Atrioventricular Block (heart block): 9 people, 90.00%
  10. Oral Disorder (mouth disease): 9 people, 90.00%

* Approximation only. Some reports may have incomplete information.

Do you take Digoxin and have Testicular atrophy?

Check whether Testicular atrophy is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

How severe was Testicular atrophy and when was it recovered:

Expand to all the drugs that have ingredients of digoxin:

Alternative drugs to, pros and cons of Digoxin:

Common Digoxin side effects:

Browse all side effects of Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Testicular atrophy treatments and more:

COVID vaccines that are related to Testicular atrophy:

Common drugs associated with Testicular atrophy:

All the drugs that are associated with Testicular atrophy:

Common conditions associated with Testicular atrophy:

All the conditions that are associated with Testicular atrophy:

How the study uses the data?

The study uses data from the FDA. It is based on digoxin (the active ingredients of Digoxin) and Digoxin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: