Diphen and Malignant ascites - a phase IV clinical study of FDA data

Summary:

Malignant ascites is reported only by a few people who take Diphen.

The phase IV clinical study analyzes which people take Diphen and have Malignant ascites. It is created by eHealthMe based on reports of 86,185 people who have side effects while taking Diphen from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On May, 26, 2023

86,185 people reported to have side effects when taking Diphen.
Among them, 4 people (0.0%) have Malignant ascites.

What is Diphen?

Diphen has active ingredients of diphenhydramine hydrochloride. eHealthMe is studying from 87,649 Diphen users for its effectiveness, alternative drugs and more.

What is Malignant ascites?

Malignant ascites (a condition in which a person with cancer has an accumulation of fluid in the abdomen) is found to be associated with 521 drugs and 275 conditions by eHealthMe.

Number of Diphen and Malignant ascites reports submitted per year:

Time on Diphen when people have Malignant ascites *:

Gender of people who have Malignant ascites when taking Diphen *:

female: 100 %
male: 0.0 %

Age of people who have Malignant ascites when taking Diphen *:

Common drugs people take besides Diphen *:

Common side effects people have besides Malignant ascites *:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 2 people, 50.00%
Breathing Difficulty: 2 people, 50.00%
Arrhythmias (irregular heartbeat): 2 people, 50.00%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 50.00%
White Blood Cell Count Decreased: 1 person, 25.00%
Pancreatitis Chronic (chronic inflammation of pancreas): 1 person, 25.00%
Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 1 person, 25.00%
Metastases To Peritoneum (cancer spreads to peritoneum): 1 person, 25.00%
Metastases To Lymph Nodes (cancer spreads to lymph node): 1 person, 25.00%
Malignant Neoplasm Progression (cancer tumour came back): 1 person, 25.00%

Common conditions people have *:

Wheezing (a high-pitched whistling sound made while you breath): 2 people, 50.00%
Fever: 2 people, 50.00%
Bacterial Infection: 2 people, 50.00%
Breast Cancer Metastatic: 2 people, 50.00%
Breast Pain: 2 people, 50.00%
Constipation: 2 people, 50.00%
Cough: 2 people, 50.00%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 50.00%
Gastric Ulcer (stomach ulcer): 2 people, 50.00%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 2 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Diphen and have Malignant ascites?

Check whether Malignant ascites is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Malignant ascites and when was it recovered:

Malignant ascites in Diphen

Expand to all the drugs that have ingredients of diphenhydramine hydrochloride:

Malignant ascites and drugs with ingredients of diphenhydramine hydrochloride

Alternative drugs to, pros and cons of Diphen:

Diphen (87,649 reports)

Common Diphen side effects:

Fatigue (feeling of tiredness): 8,422 reports
High blood pressure: 7,919 reports
Headache (pain in head): 7,440 reports
Pain: 6,769 reports
Joint pain: 6,496 reports
Drug ineffective: 6,251 reports
Sinusitis (inflammation of sinus): 5,702 reports

Browse all side effects of Diphen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Malignant ascites treatments and more:

Malignant ascites (948 reports)

COVID vaccines that are related to Malignant ascites:

All the drugs that are associated with Malignant ascites:

Malignant ascites (522 drugs)

All the conditions that are associated with Malignant ascites:

Malignant ascites (275 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Diphen) and Diphen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.