Diphen and Quincke's disease - a phase IV clinical study of FDA data

Summary:

Quincke's disease is found among people who take Diphen, especially for people who are female, 30-39 old.

The phase IV clinical study analyzes which people take Diphen and have Quincke's disease. It is created by eHealthMe based on reports of 86,185 people who have side effects when taking Diphen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Jun, 03, 2023

86,185 people reported to have side effects when taking Diphen.
Among them, 413 people (0.48%) have Quincke's disease.

What is Diphen?

Diphen has active ingredients of diphenhydramine hydrochloride. eHealthMe is studying from 87,649 Diphen users for its effectiveness, alternative drugs and more.

What is Quincke's disease?

Quincke's disease (a form of localized swelling of the deeper layers of the skin and fatty tissues beneath the skin) is found to be associated with 974 drugs and 481 conditions by eHealthMe.

Number of Diphen and Quincke's disease reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Diphen and have Quincke's disease?

Check whether Quincke's disease is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Quincke's disease and when was it recovered:

Quincke's disease in Diphen

Expand to all the drugs that have ingredients of diphenhydramine hydrochloride:

Quincke's disease and drugs with ingredients of diphenhydramine hydrochloride

Alternative drugs to, pros and cons of Diphen:

Diphen (87,649 reports)

Common Diphen side effects:

Fatigue (feeling of tiredness): 8,422 reports
High blood pressure: 7,919 reports
Headache (pain in head): 7,440 reports
Pain: 6,769 reports
Joint pain: 6,496 reports
Drug ineffective: 6,251 reports
Sinusitis (inflammation of sinus): 5,702 reports

Browse all side effects of Diphen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Quincke's disease treatments and more:

Quincke's disease (16,202 reports)

COVID vaccines that are related to Quincke's disease:

Common drugs associated with Quincke's disease:

All the drugs that are associated with Quincke's disease:

Quincke's disease (974 drugs)

Common conditions associated with Quincke's disease:

Hereditary angioedema: 1,067 reports
Preventive health care: 680 reports

All the conditions that are associated with Quincke's disease:

Quincke's disease (481 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Diphen) and Diphen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.