Diprivan and Propofol infusion syndrome - a phase IV clinical study of FDA data


Propofol infusion syndrome is found among people who take Diprivan, especially for people who are male, 20-29 old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Diprivan and have Propofol infusion syndrome. It is created by eHealthMe based on reports of 6,257 people who have side effects when taking Diprivan from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 06, 2022

6,257 people reported to have side effects when taking Diprivan.
Among them, 82 people (1.31%) have Propofol infusion syndrome.

What is Diprivan?

Diprivan has active ingredients of propofol. eHealthMe is studying from 6,276 Diprivan users for its effectiveness, alternative drugs and more.

What is Propofol infusion syndrome?

Propofol infusion syndrome is found to be associated with 182 drugs and 100 conditions by eHealthMe.

Number of Diprivan and Propofol infusion syndrome reports submitted per year:

Could Diprivan cause Propofol infusion syndrome?

Time on Diprivan when people have Propofol infusion syndrome *:

  • < 1 month: 96.88 %
  • 1 - 6 months: 3.12 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Propofol infusion syndrome when taking Diprivan *:

  • female: 35.21 %
  • male: 64.79 %

Age of people who have Propofol infusion syndrome when taking Diprivan *:

  • 0-1: 3.03 %
  • 2-9: 16.67 %
  • 10-19: 18.18 %
  • 20-29: 24.24 %
  • 30-39: 18.18 %
  • 40-49: 12.12 %
  • 50-59: 4.55 %
  • 60+: 3.03 %

Common drugs people take besides Diprivan *:

  1. Ultiva: 10 people, 12.20%
  2. Depakene: 6 people, 7.32%
  3. Levophed: 5 people, 6.10%
  4. Morphine: 5 people, 6.10%
  5. Phenytoin: 4 people, 4.88%
  6. Solu-Medrol: 3 people, 3.66%
  7. Augmentin '125': 3 people, 3.66%
  8. Zantac: 3 people, 3.66%
  9. Acyclovir: 3 people, 3.66%
  10. Norepinephrine Bitartrate: 2 people, 2.44%

Common side effects people have besides Propofol infusion syndrome *:

  1. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 32 people, 39.02%
  2. Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 20 people, 24.39%
  3. Renal Failure Acute (rapid kidney dysfunction): 14 people, 17.07%
  4. Overdose: 13 people, 15.85%
  5. Hypotension (abnormally low blood pressure): 10 people, 12.20%
  6. Arrhythmias (irregular heartbeat): 9 people, 10.98%
  7. Blood Creatine Phosphokinase Increased: 7 people, 8.54%
  8. Circulatory Collapse: 7 people, 8.54%
  9. Fever: 6 people, 7.32%
  10. Acute Kidney Failure: 6 people, 7.32%

Common conditions people have *:

  1. Sedation: 35 people, 42.68%
  2. Anaesthesia: 7 people, 8.54%
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 3.66%
  4. Injury: 3 people, 3.66%
  5. Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 3 people, 3.66%
  6. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 3 people, 3.66%
  7. Grand Mal Convulsion (a type of generalized seizure that affects the entire brain): 2 people, 2.44%
  8. Upper Respiratory Tract Infection: 2 people, 2.44%
  9. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 1 person, 1.22%
  10. Psoriasis (immune-mediated disease that affects the skin): 1 person, 1.22%

* Approximation only. Some reports may have incomplete information.

Do you take Diprivan and have Propofol infusion syndrome?

Check whether Propofol infusion syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Propofol infusion syndrome and when was it recovered:

Expand to all the drugs that have ingredients of propofol:

Alternative drugs to, pros and cons of Diprivan:

Common Diprivan side effects:

Browse all side effects of Diprivan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Propofol infusion syndrome treatments and more:

COVID vaccines that are related to Propofol infusion syndrome:

Common drugs associated with Propofol infusion syndrome:

All the drugs that are associated with Propofol infusion syndrome:

Common conditions associated with Propofol infusion syndrome:

All the conditions that are associated with Propofol infusion syndrome:

How the study uses the data?

The study uses data from the FDA. It is based on propofol (the active ingredients of Diprivan) and Diprivan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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