Donepezil and Memory loss - a phase IV clinical study of FDA data
Summary:
We study 22,455 people who have side effects when taking Donepezil. Memory loss is found, especially among people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take Nuplazid and have Parkinson's disease.
The phase IV clinical study analyzes which people take Donepezil and have Memory loss. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
What are phase IV trials?
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
22,455 people reported to have side effects when taking Donepezil.
Among them, 652 people (2.9%) have Memory loss.
What is Donepezil?
Donepezil has active ingredients of donepezil hydrochloride. It is used in dementia. Currently, eHealthMe is studying from 22,738 Donepezil users.
What is Memory loss?
Memory loss is found to be associated with 4,216 drugs and 4,279 conditions by eHealthMe. Currently, we are studying 231,910 people who have Memory loss.
Number of Donepezil and Memory loss reports submitted per year:

Time on Donepezil when people have Memory loss *:
Gender of people who have Memory loss when taking Donepezil*:
Age of people who have Memory loss when taking Donepezil *:
Common drugs people take besides Donepezil *:
Common side effects people have besides Memory loss *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Donepezil and have Memory loss?
Check whether Memory loss is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
How severe was Memory loss and when was it recovered:
Expand to all the drugs that have ingredients of donepezil hydrochloride:
Alternative drugs to, pros and cons of Donepezil:
- Donepezil (22,738 reports)
Browse all side effects of Donepezil:
a b c d e f g h i j k l m n o p q r s t u v w x y zMemory loss treatments and more:
- Memory loss (231,910 reports)
Common drugs associated with Memory loss:
- Tysabri: 11,095 reports
- Avonex: 9,871 reports
- Aspirin: 9,097 reports
- Lyrica: 8,682 reports
- Gabapentin: 7,285 reports
- Tecfidera: 7,103 reports
- Metformin: 5,864 reports
- Prednisone: 5,813 reports
- Vitamin d: 5,675 reports
- Omeprazole: 5,517 reports
All the drugs that are associated with Memory loss:
- Memory loss (4,216 drugs)
Common conditions associated with Memory loss:
- Multiple sclerosis: 34,966 reports
- Depression: 10,082 reports
- Rheumatoid arthritis: 9,111 reports
- Pain: 8,919 reports
- High blood pressure: 7,679 reports
- High blood cholesterol: 6,861 reports
All the conditions that are associated with Memory loss:
- Memory loss (4,279 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on donepezil hydrochloride (the active ingredients of Donepezil) and Donepezil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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