Doxycycline and Multi-organ failure - a phase IV clinical study of FDA data
Summary:
We study 55,714 people who have side effects when taking Doxycycline. Multi-organ failure is found, especially among people who are male, 60+ old, have been taking the drug for < 1 month, also take Lisinopril and have Sepsis.
The phase IV clinical study analyzes which people take Doxycycline and have Multi-organ failure. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
55,714 people reported to have side effects when taking Doxycycline.
Among them, 104 people (0.19%) have Multi-organ failure.
What is Doxycycline?
Doxycycline has active ingredients of doxycycline hyclate. It is used in acne. Currently, eHealthMe is studying from 59,045 Doxycycline users.
What is Multi-organ failure?
Multi-organ failure (multisystem organ failure) is found to be associated with 2,163 drugs and 2,252 conditions by eHealthMe. Currently, we are studying 32,834 people who have Multi-organ failure.
Number of Doxycycline and Multi-organ failure reports submitted per year:

Time on Doxycycline when people have Multi-organ failure *:
Gender of people who have Multi-organ failure when taking Doxycycline*:
Age of people who have Multi-organ failure when taking Doxycycline *:
Common drugs people take besides Doxycycline *:
Common side effects people have besides Multi-organ failure *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Doxycycline and have Multi-organ failure?
Check whether Multi-organ failure is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Doxycycline side effects by duration, gender and age:
- Doxycycline side effects (59,045 reports)
Multi-organ failure treatments and more:
- Multi-organ failure (32,834 reports)
Common drugs associated with Multi-organ failure:
- Trasylol: 4,281 reports
- Heparin: 2,265 reports
- Lasix: 2,190 reports
- Prednisone: 1,714 reports
- Methotrexate: 1,516 reports
- Aspirin: 1,415 reports
- Prednisolone: 1,393 reports
- Furosemide: 1,323 reports
- Cyclophosphamide: 1,159 reports
- Fentanyl: 1,011 reports
All the drugs that are associated with Multi-organ failure:
- Multi-organ failure (2,163 drugs)
Common conditions associated with Multi-organ failure:
- Rheumatoid arthritis: 1,170 reports
- High blood pressure: 1,147 reports
- Preventive health care: 849 reports
- Multiple myeloma: 686 reports
- Pain: 598 reports
- Diabetes: 561 reports
All the conditions that are associated with Multi-organ failure:
- Multi-organ failure (2,252 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Doxycycline) and Doxycycline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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