Doxycycline and Salivary gland disorder - a phase IV clinical study of FDA data


Salivary gland disorder is reported only by a few people who take Doxycycline.

The phase IV clinical study analyzes which people take Doxycycline and have Salivary gland disorder. It is created by eHealthMe based on reports of 50,846 people who have side effects while taking Doxycycline from the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jun, 30, 2022

50,846 people reported to have side effects when taking Doxycycline.
Among them, 3 people (0.01%) have Salivary gland disorder.

What is Doxycycline?

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. eHealthMe is studying from 53,895 Doxycycline users for its effectiveness, alternative drugs and more.

What is Salivary gland disorder?

Salivary gland disorder (disease of salivary gland) is found to be associated with 532 drugs and 351 conditions by eHealthMe.

Number of Doxycycline and Salivary gland disorder reports submitted per year:

Could Doxycycline cause Salivary gland disorder?

Gender of people who have Salivary gland disorder when taking Doxycycline *:

  • female: 66.67 %
  • male: 33.33 %

Age of people who have Salivary gland disorder when taking Doxycycline *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 33.33 %
  • 60+: 66.67 %

Common drugs people take besides Doxycycline *:

  1. Zometa: 1 person, 33.33%
  2. Diflucan: 1 person, 33.33%
  3. Flomax: 1 person, 33.33%
  4. Fish Oil: 1 person, 33.33%
  5. Evoxac: 1 person, 33.33%
  6. Estrogenic Substance: 1 person, 33.33%
  7. Esbriet: 1 person, 33.33%
  8. Erbitux: 1 person, 33.33%
  9. Enbrel: 1 person, 33.33%
  10. Decadron: 1 person, 33.33%

Common side effects people have besides Salivary gland disorder *:

  1. Weight Decreased: 2 people, 66.67%
  2. Depression: 2 people, 66.67%
  3. Pneumonia: 2 people, 66.67%
  4. Hypersensitivity: 2 people, 66.67%
  5. Fatigue (feeling of tiredness): 2 people, 66.67%
  6. Headache (pain in head): 2 people, 66.67%
  7. Gliosis (a process leading to scars in the central nervous system): 1 person, 33.33%
  8. Enlarged Heart: 1 person, 33.33%
  9. Enterococcal Bacteraemia (presence of bacteria lactic acid in the blood): 1 person, 33.33%
  10. Enterococcal Infection: 1 person, 33.33%

Common conditions people have *:

  1. Tonsil Cancer: 1 person, 33.33%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 33.33%
  3. Osteoporosis (bones weak and more likely to break): 1 person, 33.33%
  4. Idiopathic Pulmonary Fibrosis (chronic lung disease): 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Doxycycline and have Salivary gland disorder?

Check whether Salivary gland disorder is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of Doxycycline:

Salivary gland disorder treatments and more:

COVID vaccines that are related to Salivary gland disorder:

How severe was Salivary gland disorder and when was it recovered:

Expand to all the drugs that have ingredients of doxycycline hyclate:

All the drugs that are associated with Salivary gland disorder:

All the conditions that are associated with Salivary gland disorder:

How the study uses the data?

The study uses data from the FDA. It is based on doxycycline hyclate (the active ingredients of Doxycycline) and Doxycycline (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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