Duloxetine hydrochloride and Sinus bradycardia - a phase IV clinical study of FDA data


Sinus bradycardia is found among people who take Duloxetine hydrochloride, especially for people who are female, 40-49 old.

The phase IV clinical study analyzes which people take Duloxetine hydrochloride and have Sinus bradycardia. It is created by eHealthMe based on reports of 11,149 people who have side effects when taking Duloxetine hydrochloride from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 09, 2023

11,149 people reported to have side effects when taking Duloxetine hydrochloride.
Among them, 19 people (0.17%) have Sinus bradycardia.

What is Duloxetine hydrochloride?

Duloxetine hydrochloride has active ingredients of duloxetine hydrochloride. It is often used in depression. eHealthMe is studying from 11,973 Duloxetine hydrochloride users for its effectiveness, alternative drugs and more.

What is Sinus bradycardia?

Sinus bradycardia (an unusually slow heartbeat due to heart disease) is found to be associated with 1,787 drugs and 1,009 conditions by eHealthMe.

Number of Duloxetine hydrochloride and Sinus bradycardia reports submitted per year:

Could Duloxetine hydrochloride cause Sinus bradycardia?

Gender of people who have Sinus bradycardia when taking Duloxetine hydrochloride *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Sinus bradycardia when taking Duloxetine hydrochloride *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 52.94 %
  • 50-59: 17.65 %
  • 60+: 29.41 %

Common drugs people take besides Duloxetine hydrochloride *:

  1. Synthroid: 6 people, 31.58%
  2. Gravol: 6 people, 31.58%
  3. Benadryl: 5 people, 26.32%
  4. Cymbalta: 3 people, 15.79%
  5. Atenolol: 1 person, 5.26%
  6. Ativan: 1 person, 5.26%
  7. Calcium: 1 person, 5.26%
  8. Clonazepam: 1 person, 5.26%
  9. Hydrochlorothiazide: 1 person, 5.26%
  10. Sugammadex Sodium: 1 person, 5.26%

Common side effects people have besides Sinus bradycardia *:

  1. Malaise (a feeling of general discomfort or uneasiness): 13 people, 68.42%
  2. The Flu (the flu is caused by an influenza virus): 12 people, 63.16%
  3. Lymphocyte Count Decreased: 11 people, 57.89%
  4. Heart Rate Decreased: 11 people, 57.89%
  5. Mean Cell Haemoglobin Concentration Increased (more concentration of haemoglobin in a given volume of packed red blood cells): 11 people, 57.89%
  6. White Blood Cells Urine Positive: 11 people, 57.89%
  7. Joint Pain: 11 people, 57.89%
  8. Insomnia (sleeplessness): 11 people, 57.89%
  9. High Blood Pressure: 11 people, 57.89%
  10. Headache (pain in head): 11 people, 57.89%

Common conditions people have *:

  1. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 12 people, 63.16%
  2. Joint Pain: 7 people, 36.84%
  3. High Blood Pressure: 5 people, 26.32%
  4. Headache (pain in head): 5 people, 26.32%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 15.79%
  6. Neuromuscular Blockade Reversal: 1 person, 5.26%
  7. Bipolar Disorder (mood disorder): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Duloxetine hydrochloride and have Sinus bradycardia?

Check whether Sinus bradycardia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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How severe was Sinus bradycardia and when was it recovered:

Expand to all the drugs that have ingredients of duloxetine hydrochloride:

Alternative drugs to, pros and cons of Duloxetine hydrochloride:

Common Duloxetine hydrochloride side effects:

Browse all side effects of Duloxetine hydrochloride:

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Sinus bradycardia treatments and more:

COVID vaccines that are related to Sinus bradycardia:

Common drugs associated with Sinus bradycardia:

All the drugs that are associated with Sinus bradycardia:

Common conditions associated with Sinus bradycardia:

All the conditions that are associated with Sinus bradycardia:

How the study uses the data?

The study uses data from the FDA. It is based on duloxetine hydrochloride (the active ingredients of Duloxetine hydrochloride) and Duloxetine hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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