Who have Aseptic necrosis with Efavirenz - from FDA reports


Aseptic necrosis is found among people who take Efavirenz, especially for people who are male, 30-39 old , have been taking the drug for 6 - 12 months, also take medication Didanosine, and have Hepatitis c. This study is created by eHealthMe based on reports of 10,578 people who have side effects when taking Efavirenz from FDA, and is updated regularly.

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On Feb, 09, 2019

10,578 people reported to have side effects when taking Efavirenz.
Among them, 58 people (0.55%) have Aseptic necrosis


Number of reports submitted per year:

Could Efavirenz cause Aseptic necrosis?

Time on Efavirenz when people have Aseptic necrosis *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 6.25 %
  • 6 - 12 months: 43.75 %
  • 1 - 2 years: 37.5 %
  • 2 - 5 years: 12.5 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Aseptic necrosis when taking Efavirenz *:

  • female: 9.09 %
  • male: 90.91 %

Age of people who have Aseptic necrosis when taking Efavirenz *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 4.55 %
  • 30-39: 56.82 %
  • 40-49: 18.18 %
  • 50-59: 18.18 %
  • 60+: 2.27 %

Top conditions involved for these people *:

  1. Hepatitis C: 5 people, 8.62%
  2. Diarrhea: 3 people, 5.17%
  3. Metastases To Bone (cancer spreads to bone): 2 people, 3.45%
  4. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 2 people, 3.45%
  5. Weight Decreased: 1 person, 1.72%
  6. Pulmonary Tuberculosis (lungs tuberculosis): 1 person, 1.72%
  7. Pain In Extremity: 1 person, 1.72%
  8. Osteoporosis (bones weak and more likely to break): 1 person, 1.72%
  9. Opportunistic Infection Prophylaxis: 1 person, 1.72%
  10. Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 1.72%

Top co-used drugs for these people *:

  1. Didanosine: 29 people, 50.00%
  2. Lamivudine: 25 people, 43.10%
  3. Stavudine: 21 people, 36.21%
  4. Zidovudine: 17 people, 29.31%
  5. Tenofovir Disoproxil Fumarate: 13 people, 22.41%
  6. Kaletra: 10 people, 17.24%
  7. Norvir: 9 people, 15.52%
  8. Ritonavir: 9 people, 15.52%
  9. Epivir: 7 people, 12.07%
  10. Abacavir: 7 people, 12.07%

Top other side effects for these people *:

  1. Rashes (redness): 8 people, 13.79%
  2. Thrombocytopenia (decrease of platelets in blood): 8 people, 13.79%
  3. Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney): 7 people, 12.07%
  4. Treatment Failure: 7 people, 12.07%
  5. Cachexia (loss of weight): 7 people, 12.07%
  6. Drug Intolerance (drug sensitivity): 6 people, 10.34%
  7. Diarrhea: 6 people, 10.34%
  8. Neuropathy Peripheral (surface nerve damage): 5 people, 8.62%
  9. Pain In Extremity: 5 people, 8.62%
  10. Hypoaesthesia (reduced sense of touch or sensation): 4 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you have Aseptic necrosis while taking Efavirenz?


You are not alone:




Related studies

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Efavirenz has active ingredients of efavirenz. It is often used in hiv infection. (latest outcomes from Efavirenz 10,627 users)

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Efavirenz side effects

Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


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What would happen?

Predict new side effects and undetected conditions when you take Efavirenz and have Aseptic necrosis


FDA reports used in this study



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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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