Effexor and Fatigue - from FDA reports

Fatigue is found among people who take Effexor, especially for people who are female, 60+ old , have been taking the drug for < 1 month, also take medication Ambien, and have Pain. This study is created by eHealthMe based on reports of 74,228 people who have side effects when taking Effexor from FDA, and is updated regularly.

How to use this study: bring a copy to your health teams to ensure drug risks and benefits are fully discussed and understood.

Who is eHealthMe: we are a data analysis company who specializes in health care industry. Our original studies have been referenced on 500+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and EANO. On eHealthMe, you can research drugs and monitor them (see testimonials).

On Oct, 12, 2018

74,228 people reported to have side effects when taking Effexor.
Among them, 5,206 people (7.01%) have Fatigue

Number of reports submitted per year:

Could Effexor cause Fatigue?

Time on Effexor when people have Fatigue *:

Gender of people who have Fatigue when taking Effexor *:

  • female: 74.63 %
  • male: 25.37 %

Age of people who have Fatigue when taking Effexor *:

Top conditions involved for these people *:

  1. Pain: 464 people, 8.91%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 291 people, 5.59%
  3. High Blood Pressure: 232 people, 4.46%
  4. Insomnia (sleeplessness): 168 people, 3.23%
  5. Sleep Disorder: 164 people, 3.15%

Click here to view more results or personalize the results to your gender and age

Top co-used drugs for these people *:

  1. Ambien: 511 people, 9.82%
  2. Neurontin: 493 people, 9.47%
  3. Xanax: 491 people, 9.43%
  4. Zometa: 465 people, 8.93%
  5. Synthroid: 460 people, 8.84%

Click here to view more results or personalize the results to your gender and age

Top other side effects for these people *:

  1. Nausea (feeling of having an urge to vomit): 1,455 people, 27.95%
  2. Weakness: 1,293 people, 24.84%
  3. Headache (pain in head): 1,285 people, 24.68%
  4. Dizziness: 1,141 people, 21.92%
  5. Pain: 1,094 people, 21.01%

Click here to view more results or personalize the results to your gender and age

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study

Do you have Fatigue while taking Effexor?

You are not alone:

Related studies


Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. (latest outcomes from Effexor 80,229 users)


Fatigue (feeling of tiredness) has been reported by people with multiple sclerosis, rheumatoid arthritis, high blood pressure, hepatitis c, depression (latest reports from 491,634 Fatigue patients).

Drugs that are associated with Fatigue
Fatigue (4,369 drugs)
Could your condition cause Fatigue
Fatigue (5,459 conditions)
Effexor side effects
Browse all side effects of Effexor
a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

What would happen?

Predict new side effects and undetected conditions when you take Effexor and have Fatigue

Recent updates

General studies

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.