Effexor and Z-e syndrome - a phase IV clinical study of FDA data
Summary:
We study 88,368 people who have side effects when taking Effexor. Z-e syndrome is found, especially among people who are female, 50-59 old, also take Aspirin.
The phase IV clinical study analyzes which people take Effexor and have Z-e syndrome. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
88,368 people reported to have side effects when taking Effexor.
Among them, 1 person (0.0%) has Z-e syndrome.
What is Effexor?
Effexor has active ingredients of venlafaxine hydrochloride. It is used in depression. Currently, eHealthMe is studying from 97,783 Effexor users.
What is Z-e syndrome?
Z-e syndrome (increased production of the hormone gastrin from a small tumour of pancreas) is found to be associated with 152 drugs and 173 conditions by eHealthMe. Currently, we are studying 1,239 people who have Z-e syndrome.
Number of Effexor and Z-e syndrome reports submitted per year:

Gender of people who have Z-e syndrome when taking Effexor *:
- female: 100 %
- male: 0.0 %
Age of people who have Z-e syndrome when taking Effexor *:
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 100 %
- 60+: 0.0 %
Common drugs people take besides Effexor *:
- Metoprolol Tartrate: 1 person, 100.00%
- Lipitor: 1 person, 100.00%
- Brilinta: 1 person, 100.00%
- Aspirin: 1 person, 100.00%
Common side effects people have besides Z-e syndrome *:
- Throat Irritation: 1 person, 100.00%
- Nausea And Vomiting: 1 person, 100.00%
- Heart Attack: 1 person, 100.00%
- Chest Pain: 1 person, 100.00%
- Abdominal Pain Upper: 1 person, 100.00%
* Approximation only. Some reports may have incomplete information.
Do you take Effexor and have Z-e syndrome?
Check whether Z-e syndrome is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Effexor side effects by duration, gender and age:
- Effexor side effects (97,783 reports)
Z-e syndrome treatments and more:
- Z-e syndrome (1,239 reports)
All the drugs that are associated with Z-e syndrome:
- Z-e syndrome (152 drugs)
All the conditions that are associated with Z-e syndrome:
- Z-e syndrome (173 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on venlafaxine hydrochloride (the active ingredients of Effexor) and Effexor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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