Emsam and Depression - a phase IV clinical study of FDA data

Summary:

We study 1,591 people who have side effects when taking Emsam. Depression is found, especially among people who are female, 60+ old, have been taking the drug for < 1 month, also take Klonopin and have Stress and anxiety.

The phase IV clinical study analyzes which people take Emsam and have Depression. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Aug, 27, 2023

1,591 people reported to have side effects when taking Emsam.
Among them, 121 people (7.61%) have Depression.

What is Emsam?

Emsam has active ingredients of selegiline. It is used in depression. Currently, eHealthMe is studying from 1,840 Emsam users.

What is Depression?

Depression is found to be associated with 4,227 drugs and 4,029 conditions by eHealthMe. Currently, we are studying 628,541 people who have Depression.

Number of Emsam and Depression reports submitted per year:

* Approximation only. Some reports may have incomplete information.

Do you take Emsam and have Depression?

Check whether Depression is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Pang, T., & Gudi, A., "Chest pain following the use of fluvoxamine in depression", Proceedings of Singapore Healthcare, 2018 Jan .

Related studies

Emsam side effects by duration, gender and age:

Emsam side effects (1,840 reports)

Depression treatments and more:

Depression (628,541 reports)

Common drugs associated with Depression:

All the drugs that are associated with Depression:

Depression (4,227 drugs)

Common conditions associated with Depression:

Multiple sclerosis: 20,384 reports
Pain: 12,961 reports
High blood pressure: 10,315 reports
Rheumatoid arthritis: 10,067 reports

All the conditions that are associated with Depression:

Depression (4,029 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on selegiline (the active ingredients of Emsam) and Emsam (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.