Entresto and Atypical pneumonia - a phase IV clinical study of FDA data


Atypical pneumonia is found among people who take Entresto, especially for people who are male, 60+ old, have been taking the drug for < 1 month.

The phase IV clinical study analyzes which people take Entresto and have Atypical pneumonia. It is created by eHealthMe based on reports of 91,668 people who have side effects when taking Entresto from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 07, 2022

91,668 people reported to have side effects when taking Entresto.
Among them, 8 people (0.01%) have Atypical pneumonia.

What is Entresto?

Entresto has active ingredients of sacubitril; valsartan. eHealthMe is studying from 91,934 Entresto users for its effectiveness, alternative drugs and more.

What is Atypical pneumonia?

Atypical pneumonia (acute respiratory disease marked by high fever and coughing) is found to be associated with 1,193 drugs and 804 conditions by eHealthMe.

Number of Entresto and Atypical pneumonia reports submitted per year:

Could Entresto cause Atypical pneumonia?

Time on Entresto when people have Atypical pneumonia *:

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Atypical pneumonia when taking Entresto *:

  • female: 50 %
  • male: 50 %

Age of people who have Atypical pneumonia when taking Entresto *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

Common drugs people take besides Entresto *:

  1. Furosemide: 1 person, 12.50%

Common side effects people have besides Atypical pneumonia *:

  1. Weakness: 3 people, 37.50%
  2. The Flu (the flu is caused by an influenza virus): 2 people, 25.00%
  3. Cough: 2 people, 25.00%
  4. Dehydration (dryness resulting from the removal of water): 2 people, 25.00%
  5. Malaise (a feeling of general discomfort or uneasiness): 2 people, 25.00%
  6. Dizziness: 2 people, 25.00%
  7. Feeling Abnormal: 2 people, 25.00%
  8. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 25.00%
  9. Herpes Zoster: 1 person, 12.50%
  10. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 12.50%

Common conditions people have *:

  1. Left Ventricular Failure (left ventricle fails to contract forcefully): 1 person, 12.50%
  2. Cardiac Failure Chronic: 1 person, 12.50%
  3. Cardiac Failure: 1 person, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Entresto and have Atypical pneumonia?

Check whether Atypical pneumonia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Atypical pneumonia and when was it recovered:

Expand to all the drugs that have ingredients of sacubitril; valsartan:

Alternative drugs to, pros and cons of Entresto:

Common Entresto side effects:

Browse all side effects of Entresto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Atypical pneumonia treatments and more:

COVID vaccines that are related to Atypical pneumonia:

Common drugs associated with Atypical pneumonia:

All the drugs that are associated with Atypical pneumonia:

Common conditions associated with Atypical pneumonia:

All the conditions that are associated with Atypical pneumonia:

How the study uses the data?

The study uses data from the FDA. It is based on sacubitril; valsartan (the active ingredients of Entresto) and Entresto (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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