Epipen and Injection site haematoma - a phase IV clinical study of FDA data

• Epipen (20,459 reports)

• Abdominal discomfort: 182 reports
• Abdominal distension: 119 reports
• Abdominal pain: 260 reports
• Abdominal pain upper: 207 reports
• Accidental exposure: 566 reports
• Acute kidney failure: 121 reports
• Anaemia (lack of blood): 135 reports
• Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 682 reports
• Angioedema (rapid swelling of the dermis): 144 reports
• Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 183 reports
• Arrhythmias (irregular heartbeat): 244 reports
• Asthma: 672 reports
• Back pain: 349 reports
• Blood pressure systolic increased: 144 reports
• Breathing difficulty: 1,112 reports
• Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 547 reports
• Burning sensation: 140 reports
• Chest pain: 629 reports
• Chills (felling of cold): 264 reports
• Chronic kidney disease: 165 reports
• Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe): 136 reports
• Condition: 160 reports
• Constipation: 167 reports
• Cough: 685 reports
• Death: 222 reports
• Dehydration (dryness resulting from the removal of water): 169 reports
• Depression: 322 reports
• Device failure: 962 reports
• Diarrhea: 582 reports
• Dizziness: 692 reports
• Drowsiness: 298 reports
• Drug hypersensitivity: 351 reports
• Drug ineffective: 1,138 reports
• Eye swelling: 101 reports
• Fainting (loss of consciousness and postural tone): 131 reports
• Fall: 431 reports
• Fatigue (feeling of tiredness): 1,286 reports
• Feeling hot: 108 reports
• Fever: 637 reports
• Fibromyalgia (a long-term condition which causes pain all over the body): 104 reports
• Gait disturbance: 154 reports
• Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 175 reports
• Hair loss: 164 reports
• Headache (pain in head): 1,394 reports
• Head injury: 361 reports
• Heart attack: 118 reports
• Heart palpitations (feelings or sensations that your heart is pounding or racing): 262 reports
• Heart rate decreased: 103 reports
• Heart rate increased: 292 reports
• Hereditary angioedema (recurrent episodes of severe swelling): 379 reports
• High blood pressure: 672 reports
• Hoarseness or changing voice: 141 reports
• Hospitalisation: 148 reports
• Hyperhidrosis (abnormally increased sweating): 179 reports
• Hypersensitivity: 616 reports
• Hypoaesthesia (reduced sense of touch or sensation): 304 reports
• Hypotension (abnormally low blood pressure): 297 reports
• Indigestion: 126 reports
• Infection: 240 reports
• Influenza like illness: 174 reports
• Infusion related reaction: 167 reports
• Infusion site erythema (reddening of the skin at infusion site): 114 reports
• Infusion site pain: 162 reports
• Infusion site swelling: 136 reports
• Injection site bruising: 148 reports
• Injection site erythema (redness at injection site): 162 reports
• Injection site haemorrhage (bleeding from injection site): 196 reports
• Injection site pain: 608 reports
• Injection site pallor (an unhealthy pale appearance at injection site): 140 reports
• Injection site swelling: 150 reports
• Insomnia (sleeplessness): 361 reports
• Itching: 642 reports
• Joint pain: 537 reports
• Joint swelling: 127 reports
• Lip swelling: 158 reports
• Loss of consciousness: 212 reports
• Lung infection: 108 reports
• Malaise (a feeling of general discomfort or uneasiness): 604 reports
• Memory loss: 244 reports
• Migraine (headache): 280 reports
• Muscle aches (muscle pain): 213 reports
• Muscle spasms (muscle contraction): 263 reports
• Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 202 reports
• Nasopharyngitis (inflammation of the nasopharynx): 503 reports
• Nausea (feeling of having an urge to vomit): 1,087 reports
• Nausea and vomiting: 632 reports
• Oedema peripheral (superficial swelling): 148 reports
• Oropharyngeal pain: 298 reports
• Otitis (ear infection): 200 reports
• Oxygen saturation decreased: 114 reports
• Pain: 943 reports
• Pain in extremity: 442 reports
• Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 232 reports
• Peripheral swelling: 239 reports
• Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal): 136 reports
• Pneumonia: 614 reports
• Pre-existing condition improved: 111 reports
• Productive cough: 131 reports
• Pulmonary embolism (blockage of the main artery of the lung): 127 reports
• Rashes (redness): 931 reports
• Respiratory tract infection: 130 reports
• Seizures (abnormal excessive or synchronous neuronal activity in the brain): 125 reports
• Sepsis (a severe blood infection that can lead to organ failure and death): 130 reports
• Sinusitis (inflammation of sinus): 1,244 reports
• Skin blushing/flushing (a sudden reddening of the face, neck): 168 reports
• Speech disorder: 102 reports
• Stress and anxiety: 690 reports
• Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 130 reports
• Swallowing difficulty: 210 reports
• Swelling: 213 reports
• Swelling face: 208 reports
• Swollen tongue (swelling of tongue): 204 reports
• The flu (the flu is caused by an influenza virus): 312 reports
• Therapeutic response unexpected: 115 reports
• Throat irritation: 140 reports
• Throat tightness: 178 reports
• Thrombosis (formation of a blood clot inside a blood vessel): 132 reports
• Tremor (trembling or shaking movements in one or more parts of your body): 315 reports
• Upper respiratory tract infection: 450 reports
• Urinary tract infection: 521 reports
• Urticaria (rash of round, red welts on the skin that itch intensely): 687 reports
• Visual impairment: 122 reports
• Weakness: 495 reports
• Weight decreased: 389 reports
• Weight increased: 313 reports
• Wheezing (a high-pitched whistling sound made while you breath): 267 reports

• Injection site haematoma (16,495 reports)

• Acetaminophen: 137 reports
• Albuterol: 118 reports
• Ambien: 117 reports
• Amlodipine: 101 reports
• Arava: 122 reports
• Aspirin: 482 reports
• Atenolol: 141 reports
• Avonex: 659 reports
• Baclofen: 139 reports
• Betaseron: 217 reports
• Botox: 104 reports
• Byetta: 183 reports
• Celebrex: 137 reports
• Cimzia: 136 reports
• Clonazepam: 118 reports
• Copaxone: 160 reports
• Coumadin: 241 reports
• Crestor: 103 reports
• Cymbalta: 169 reports
• Enbrel: 6,529 reports
• Extavia: 220 reports
• Fish oil: 174 reports
• Folic acid: 498 reports
• Forteo: 1,173 reports
• Gabapentin: 219 reports
• Humira: 2,849 reports
• Hydrochlorothiazide: 148 reports
• Ibuprofen: 247 reports
• Lantus: 262 reports
• Lasix: 140 reports
• Leflunomide: 110 reports
• Levothyroxine sodium: 193 reports
• Lexapro: 109 reports
• Lipitor: 164 reports
• Lisinopril: 253 reports
• Lovenox: 185 reports
• Metformin: 314 reports
• Methotrexate: 1,781 reports
• Metoprolol tartrate: 108 reports
• Naproxen: 114 reports
• Neurontin: 133 reports
• Nexium: 244 reports
• Omeprazole: 286 reports
• Plaquenil: 278 reports
• Plavix: 197 reports
• Prednisone: 671 reports
• Prilosec: 160 reports
• Rebif: 924 reports
• Sandostatin: 228 reports
• Sandostatin lar: 195 reports
• Simvastatin: 252 reports
• Singulair: 146 reports
• Sulfasalazine: 109 reports
• Synthroid: 289 reports
• Tramadol: 144 reports
• Tylenol: 203 reports
• Vicodin: 132 reports
• Victoza: 370 reports
• Vitamins: 194 reports
• Xanax: 142 reports
• Zoloft: 107 reports

All the drugs that are associated with Injection site haematoma:

• Injection site haematoma (1,124 drugs)

• Acid reflux: 180 reports
• Ankylosing spondylitis: 487 reports
• Anxiety: 205 reports
• Anxiolytic therapy: 203 reports
• Arthritis: 103 reports
• Asthma: 219 reports
• Birth control: 108 reports
• Blood cholesterol abnormal: 324 reports
• Blood cholesterol increased: 315 reports
• Blood pressure - high: 464 reports
• Blood pressure increased: 446 reports
• Blood triglycerides abnormal: 315 reports
• Chronic asthma: 184 reports
• Contraception: 110 reports
• Crohns: 993 reports
• Crohn's disease: 986 reports
• Crohns disease: 993 reports
• Depression: 292 reports
• Diabetes: 220 reports
• Diabetes mellitus: 215 reports
• Diabetes mellitus management: 220 reports
• Diabetes mellitus non-insulin-dependent: 641 reports
• Diabetes - type 2: 688 reports
• Diabetic type 2: 688 reports
• Dm: 215 reports
• Dyslipidemia: 324 reports
• Dyssomnia: 136 reports
• Gastroesophageal reflux disease: 180 reports
• Gastro-oesophageal reflux disease: 180 reports
• Gastrooesophageal reflux disease: 180 reports
• Gerd: 180 reports
• Granulomatous ileocolitis: 981 reports
• Hbp: 446 reports
• Healthy living: 148 reports
• High blood cholesterol: 315 reports
• High blood cholesterol and triglycerides: 324 reports
• High blood pressure: 464 reports
• Hypercholesterolemia: 316 reports
• Hyperlipidemia: 324 reports
• Hypersensitivity: 109 reports
• Hypertension: 438 reports
• Hypothyroid: 144 reports
• Hypothyroidism: 144 reports
• Ileitis: 993 reports
• Ileitis aggravated: 986 reports
• Insomnia: 133 reports
• Insomnia concerns: 136 reports
• Insomnia exacerbated: 136 reports
• Juvenile arthritis: 149 reports
• Lipoprotein test: 324 reports
• Low thyroid: 142 reports
• Migraine: 122 reports
• Migraines: 125 reports
• Ms: 1,688 reports
• Multiple sclerosis: 1,688 reports
• Myxedema: 142 reports
• Osteoporosis: 1,065 reports
• Pain: 406 reports
• Pain management: 419 reports
• Psoriasis: 1,739 reports
• Psoriatic arthropathy: 1,247 reports
• Psoriatic arthropathy aggravated: 1,247 reports
• Regional enteritis: 981 reports
• Relapsing-remitting multiple sclerosis: 261 reports
• Rheumatoid arthritis: 5,044 reports
• Rrms: 259 reports
• Sleeping: 133 reports
• Sleeping difficulty: 136 reports
• Spondylarthropathy: 487 reports
• Spondylitis: 487 reports
• Stress: 205 reports
• Stress and anxiety: 203 reports
• Tension: 203 reports
• Type 2 diabetes: 688 reports
• Type 2 diabetes mellitus: 685 reports
• Underactive thyroid: 142 reports
• Vitamin supplementation: 148 reports

All the conditions that are associated with Injection site haematoma:

• Injection site haematoma (812 conditions)

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).