Epivir and Hyperglycemia - a phase IV clinical study of FDA data


Hyperglycemia is found among people who take Epivir, especially for people who are male, 40-49 old, have been taking the drug for 5 - 10 years.

The phase IV clinical study analyzes which people take Epivir and have Hyperglycemia. It is created by eHealthMe based on reports of 16,085 people who have side effects when taking Epivir from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 28, 2023

16,085 people reported to have side effects when taking Epivir.
Among them, 45 people (0.28%) have Hyperglycemia.

What is Epivir?

Epivir has active ingredients of lamivudine. It is often used in hiv infection. eHealthMe is studying from 16,132 Epivir users for its effectiveness, alternative drugs and more.

What is Hyperglycemia?

Hyperglycemia (high blood sugar) is found to be associated with 2,867 drugs and 2,398 conditions by eHealthMe.

Number of Epivir and Hyperglycemia reports submitted per year:

Could Epivir cause Hyperglycemia?

Time on Epivir when people have Hyperglycemia *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 10 %
  • 6 - 12 months: 20 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 20 %
  • 5 - 10 years: 30 %
  • 10+ years: 20 %

Gender of people who have Hyperglycemia when taking Epivir *:

  • female: 26.67 %
  • male: 73.33 %

Age of people who have Hyperglycemia when taking Epivir *:

  • 0-1: 3.33 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 13.33 %
  • 40-49: 63.33 %
  • 50-59: 20.0 %
  • 60+: 0.0 %

Common drugs people take besides Epivir *:

  1. Retrovir: 23 people, 51.11%
  2. Kaletra: 22 people, 48.89%
  3. Norvir: 21 people, 46.67%
  4. Viracept: 19 people, 42.22%
  5. Zerit: 18 people, 40.00%
  6. Viread: 18 people, 40.00%
  7. Truvada: 16 people, 35.56%
  8. Bactrim: 16 people, 35.56%
  9. Isentress: 16 people, 35.56%
  10. Videx: 15 people, 33.33%

Common side effects people have besides Hyperglycemia *:

  1. Cough: 16 people, 35.56%
  2. Alanine Aminotransferase Increased: 16 people, 35.56%
  3. High Blood Cholesterol: 16 people, 35.56%
  4. Anaemia (lack of blood): 16 people, 35.56%
  5. Diarrhea: 15 people, 33.33%
  6. Kidney Stones: 15 people, 33.33%
  7. Constipation: 15 people, 33.33%
  8. Glycosuria (excretion of glucose into the urine): 15 people, 33.33%
  9. Neuropathy Peripheral (surface nerve damage): 15 people, 33.33%
  10. Facial Pain: 14 people, 31.11%

Common conditions people have *:

  1. Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 5 people, 11.11%
  2. Insomnia (sleeplessness): 4 people, 8.89%
  3. Bipolar Disorder (mood disorder): 3 people, 6.67%
  4. Adrenal Insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids): 2 people, 4.44%
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 4.44%
  6. Diabetes: 2 people, 4.44%
  7. The Flu (the flu is caused by an influenza virus): 2 people, 4.44%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.44%
  9. Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 2 people, 4.44%
  10. Mycobacterium Avium Complex Infection: 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.

Do you take Epivir and have Hyperglycemia?

Check whether Hyperglycemia is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

How severe was Hyperglycemia and when was it recovered:

Expand to all the drugs that have ingredients of lamivudine:

Alternative drugs to, pros and cons of Epivir:

Common Epivir side effects:

Browse all side effects of Epivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Hyperglycemia treatments and more:

COVID vaccines that are related to Hyperglycemia:

Common drugs associated with Hyperglycemia:

All the drugs that are associated with Hyperglycemia:

Common conditions associated with Hyperglycemia:

All the conditions that are associated with Hyperglycemia:

How the study uses the data?

The study uses data from the FDA. It is based on lamivudine (the active ingredients of Epivir) and Epivir (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe: