Escitalopram and Sick sinus syndrome - a phase IV clinical study of FDA data


Sick sinus syndrome is found among people who take Escitalopram, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years.

The phase IV clinical study analyzes which people take Escitalopram and have Sick sinus syndrome. It is created by eHealthMe based on reports of 59,851 people who have side effects when taking Escitalopram from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 29, 2022

59,851 people reported to have side effects when taking Escitalopram.
Among them, 15 people (0.03%) have Sick sinus syndrome.

What is Escitalopram?

Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 62,402 Escitalopram users for its effectiveness, alternative drugs and more.

What is Sick sinus syndrome?

Sick sinus syndrome (a collection of heart rhythm disorders) is found to be associated with 1,303 drugs and 734 conditions by eHealthMe.

Number of Escitalopram and Sick sinus syndrome reports submitted per year:

Could Escitalopram cause Sick sinus syndrome?

Time on Escitalopram when people have Sick sinus syndrome *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Sick sinus syndrome when taking Escitalopram *:

  • female: 72.73 %
  • male: 27.27 %

Age of people who have Sick sinus syndrome when taking Escitalopram *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 50 %
  • 60+: 50 %

Common drugs people take besides Escitalopram *:

  1. Niaspan: 3 people, 20.00%
  2. Fish Oil: 3 people, 20.00%
  3. Crestor: 3 people, 20.00%
  4. Axiron: 3 people, 20.00%
  5. Amlodipine: 3 people, 20.00%
  6. Bystolic: 2 people, 13.33%
  7. Zopiclone: 1 person, 6.67%
  8. Nexium: 1 person, 6.67%

Common side effects people have besides Sick sinus syndrome *:

  1. Dizziness: 12 people, 80.00%
  2. Fainting (loss of consciousness and postural tone): 12 people, 80.00%
  3. Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 11 people, 73.33%
  4. Mood Swings (an extreme or rapid change in mood): 11 people, 73.33%
  5. Anaemia (lack of blood): 11 people, 73.33%
  6. Anger: 11 people, 73.33%
  7. Bradycardia (abnormally slow heart action): 11 people, 73.33%
  8. Bruxism (habitual grinding of the teeth, typically during sleep): 11 people, 73.33%
  9. Coordination Abnormal (abnormal movement): 11 people, 73.33%
  10. Dyskinesia (abnormality or impairment of voluntary movement): 11 people, 73.33%

Common conditions people have *:

  1. Prostatic Disorder: 3 people, 20.00%
  2. High Blood Cholesterol: 3 people, 20.00%
  3. Blood Testosterone Decreased: 3 people, 20.00%
  4. Prostatomegaly (enlargement of the prostate): 2 people, 13.33%
  5. Irritability: 1 person, 6.67%
  6. Insomnia (sleeplessness): 1 person, 6.67%
  7. Indigestion: 1 person, 6.67%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
  9. Dementia (madness): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Escitalopram and have Sick sinus syndrome?

Check whether Sick sinus syndrome is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

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How severe was Sick sinus syndrome and when was it recovered:

Expand to all the drugs that have ingredients of escitalopram oxalate:

Alternative drugs to, pros and cons of Escitalopram:

Common Escitalopram side effects:

Browse all side effects of Escitalopram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sick sinus syndrome treatments and more:

COVID vaccines that are related to Sick sinus syndrome:

Common drugs associated with Sick sinus syndrome:

All the drugs that are associated with Sick sinus syndrome:

Common conditions associated with Sick sinus syndrome:

All the conditions that are associated with Sick sinus syndrome:

How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate (the active ingredients of Escitalopram) and Escitalopram (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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