Estrace and Salivary hypersecretion - a phase IV clinical study of FDA data

Summary:

Salivary hypersecretion is found among people who take Estrace, especially for people who are female, 60+ old.

The phase IV clinical study analyzes which people take Estrace and have Salivary hypersecretion. It is created by eHealthMe based on reports of 15,335 people who have side effects when taking Estrace from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Aug, 14, 2022

15,335 people reported to have side effects when taking Estrace.
Among them, 10 people (0.07%) have Salivary hypersecretion.


What is Estrace?

Estrace has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 15,217 Estrace users for its effectiveness, alternative drugs and more.

What is Salivary hypersecretion?

Salivary hypersecretion (excess saliva secretion) is found to be associated with 1,946 drugs and 1,167 conditions by eHealthMe.

Number of Estrace and Salivary hypersecretion reports submitted per year:

Could Estrace cause Salivary hypersecretion?

Gender of people who have Salivary hypersecretion when taking Estrace *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Salivary hypersecretion when taking Estrace *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 40 %
  • 50-59: 0.0 %
  • 60+: 60 %

Common drugs people take besides Estrace *:

  1. Ditropan: 3 people, 30.00%
  2. Effexor Xr: 3 people, 30.00%
  3. Evista: 3 people, 30.00%
  4. Nasonex: 3 people, 30.00%
  5. Lyrica: 2 people, 20.00%
  6. Synthroid: 2 people, 20.00%
  7. Glutamine: 2 people, 20.00%
  8. Actemra: 2 people, 20.00%
  9. Strattera: 1 person, 10.00%
  10. Sertraline: 1 person, 10.00%

Common side effects people have besides Salivary hypersecretion *:

  1. Swallowing Difficulty: 4 people, 40.00%
  2. Itching: 3 people, 30.00%
  3. Headache (pain in head): 3 people, 30.00%
  4. Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 30.00%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 30.00%
  6. Weight Increased: 3 people, 30.00%
  7. High Blood Pressure: 3 people, 30.00%
  8. Tongue Paralysis (loss of function of tongue): 3 people, 30.00%
  9. Drug Ineffective: 3 people, 30.00%
  10. Drooling (drop saliva uncontrollably from the mouth): 3 people, 30.00%

Common conditions people have *:

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 30.00%
  2. Constipation: 2 people, 20.00%
  3. Parkinson's Disease: 1 person, 10.00%
  4. Neoplasm Malignant (cancer tumour): 1 person, 10.00%
  5. Indigestion: 1 person, 10.00%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 10.00%
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Estrace and have Salivary hypersecretion?

Check whether Salivary hypersecretion is associated with a drug or a condition

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

How severe was Salivary hypersecretion and when was it recovered:

Expand to all the drugs that have ingredients of estradiol:

Alternative drugs to, pros and cons of Estrace:

Common Estrace side effects:

Browse all side effects of Estrace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Salivary hypersecretion treatments and more:

COVID vaccines that are related to Salivary hypersecretion:

Common drugs associated with Salivary hypersecretion:

All the drugs that are associated with Salivary hypersecretion:

Common conditions associated with Salivary hypersecretion:

All the conditions that are associated with Salivary hypersecretion:

How the study uses the data?

The study uses data from the FDA. It is based on estradiol (the active ingredients of Estrace) and Estrace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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