Estradiol and Night sweats - a phase IV clinical study of FDA data
Summary:
We study 13,397 people who have side effects when taking Estradiol. Night sweats is found, especially among people who are female, 50-59 old, have been taking the drug for < 1 month, also take Paroxetine hydrochloride and have Migraine.
The phase IV clinical study analyzes which people take Estradiol and have Night sweats. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
13,397 people reported to have side effects when taking Estradiol.
Among them, 123 people (0.92%) have Night sweats.
What is Estradiol?
Estradiol has active ingredients of estradiol. It is used in hormone replacement therapy. Currently, eHealthMe is studying from 14,917 Estradiol users.
What is Night sweats?
Night sweats (sweating in night) is found to be associated with 2,467 drugs and 1,678 conditions by eHealthMe. Currently, we are studying 37,945 people who have Night sweats.
Number of Estradiol and Night sweats reports submitted per year:

Time on Estradiol when people have Night sweats *:
Gender of people who have Night sweats when taking Estradiol*:
Age of people who have Night sweats when taking Estradiol *:
Common drugs people take besides Estradiol *:
Common side effects people have besides Night sweats *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Estradiol and have Night sweats?
Check whether Night sweats is associated with a drug or a conditionHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Murday HK, Rusli FD, Blandy C, Vollenhoven B, "Night sweats: it may be hemochromatosis", Climacteric, 2016 Jul .
Related studies
Estradiol side effects by duration, gender and age:
- Estradiol side effects (14,917 reports)
Night sweats treatments and more:
- Night sweats (37,945 reports)
Common drugs associated with Night sweats:
- Prednisone: 3,388 reports
- Humira: 2,330 reports
- Enbrel: 2,263 reports
- Methotrexate: 2,094 reports
- Tylenol: 1,853 reports
- Aspirin: 1,807 reports
- Ibu: 1,629 reports
- Ibuprofen: 1,627 reports
- Profen: 1,627 reports
- Pantoprazole: 1,458 reports
All the drugs that are associated with Night sweats:
- Night sweats (2,467 drugs)
Common conditions associated with Night sweats:
- Rheumatoid arthritis: 2,659 reports
- Depression: 1,390 reports
- Multiple sclerosis: 1,372 reports
- Pain: 1,335 reports
- High blood pressure: 1,097 reports
- Crohn's disease: 904 reports
- Stress and anxiety: 838 reports
All the conditions that are associated with Night sweats:
- Night sweats (1,678 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on estradiol (the active ingredients of Estradiol) and Estradiol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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